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The map label for this gene is ccdA [H]

Identifier: 52785794

GI number: 52785794

Start: 1982379

End: 1983086

Strand: Direct

Name: ccdA [H]

Synonym: BLi02040

Alternate gene names: 52785794

Gene position: 1982379-1983086 (Clockwise)

Preceding gene: 52785792

Following gene: 52785795

Centisome position: 46.95

GC content: 46.19

Gene sequence:

>708_bases
ATGGCTGATATCAATTATATTCTCGCTTTCGGTGCAGGGTTTCTATCGTTTATTTCGCCATGCTGCCTGCCGCTTTATCC
CGCTTTTTTATCATATATTACCGGTGTCAGCATGAGTGAAATCCATTCTGACAAACTTATGTTTCAAAAAAGGAGCTTGG
TACATACGGTCTTTTTCCTGATCGGCTTTTCGATGATCTTTGTGGCACTCGGCTACAGCACGTCGCTTGTCGGGTCGTTT
TTTAAGGATTATCATCAGCTCATCAGGCAGCTTGGTGCGGTTTTTATCATCTTTTTCGGATTTGTCACTTTGGGGGTTTT
TAAGCCTGAATTTTTAATGAAAGAAAGGCGCCTCCAATTTAAAAACAGGCCTGGAGGTCTGCTCGGTTCCATCGGAATCG
GAATGGCATTTGCCGCCGGCTGGACGCCCTGCACCGGCCCGATTCTTGCAGCGGTTATTGCACTCGCCGGAACGAACCCG
ATGTCGGCCGTGCCTTATATGGCGCTTTATGCACTCGGATTCAGCTTGCCGTTTCTGCTTCTGTCTTTTTTCATTACAAA
GATGAAATGGCTTCGGAAGCATCAGCTCATCATCATGAAGATCGGCGGAGTTGCAATGATTGTAGTCGGCATCCTGCTGT
TCTTTGACTGGATGACGAAAATCATTATCGTATTGTCAAGCCTGTTCGGCGATTTCAGAGGCTTTTAA

Upstream 100 bases:

>100_bases
ATCAACATCCTTTTTTGTGATATGTTAGGAAATTGAAATGTAATTGTCATATCAAATGATTTTCTTTCATGGTATTCCAA
AAAATAGAAGGGAGAAAGAG

Downstream 100 bases:

>100_bases
ACTTTGCTAAGGACCGCCTTGGTTTTTTGTTACAATAGGACTTATTCACAGCAAAACTGAATAATGATGTTGGAGGGGAG
TATGACAAGGGTTTTAATTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MADINYILAFGAGFLSFISPCCLPLYPAFLSYITGVSMSEIHSDKLMFQKRSLVHTVFFLIGFSMIFVALGYSTSLVGSF
FKDYHQLIRQLGAVFIIFFGFVTLGVFKPEFLMKERRLQFKNRPGGLLGSIGIGMAFAAGWTPCTGPILAAVIALAGTNP
MSAVPYMALYALGFSLPFLLLSFFITKMKWLRKHQLIIMKIGGVAMIVVGILLFFDWMTKIIIVLSSLFGDFRGF

Sequences:

>Translated_235_residues
MADINYILAFGAGFLSFISPCCLPLYPAFLSYITGVSMSEIHSDKLMFQKRSLVHTVFFLIGFSMIFVALGYSTSLVGSF
FKDYHQLIRQLGAVFIIFFGFVTLGVFKPEFLMKERRLQFKNRPGGLLGSIGIGMAFAAGWTPCTGPILAAVIALAGTNP
MSAVPYMALYALGFSLPFLLLSFFITKMKWLRKHQLIIMKIGGVAMIVVGILLFFDWMTKIIIVLSSLFGDFRGF
>Mature_234_residues
ADINYILAFGAGFLSFISPCCLPLYPAFLSYITGVSMSEIHSDKLMFQKRSLVHTVFFLIGFSMIFVALGYSTSLVGSFF
KDYHQLIRQLGAVFIIFFGFVTLGVFKPEFLMKERRLQFKNRPGGLLGSIGIGMAFAAGWTPCTGPILAAVIALAGTNPM
SAVPYMALYALGFSLPFLLLSFFITKMKWLRKHQLIIMKIGGVAMIVVGILLFFDWMTKIIIVLSSLFGDFRGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26102; Mature: 25971

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADINYILAFGAGFLSFISPCCLPLYPAFLSYITGVSMSEIHSDKLMFQKRSLVHTVFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IGFSMIFVALGYSTSLVGSFFKDYHQLIRQLGAVFIIFFGFVTLGVFKPEFLMKERRLQF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KNRPGGLLGSIGIGMAFAAGWTPCTGPILAAVIALAGTNPMSAVPYMALYALGFSLPFLL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LSFFITKMKWLRKHQLIIMKIGGVAMIVVGILLFFDWMTKIIIVLSSLFGDFRGF
HHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADINYILAFGAGFLSFISPCCLPLYPAFLSYITGVSMSEIHSDKLMFQKRSLVHTVFFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IGFSMIFVALGYSTSLVGSFFKDYHQLIRQLGAVFIIFFGFVTLGVFKPEFLMKERRLQF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KNRPGGLLGSIGIGMAFAAGWTPCTGPILAAVIALAGTNPMSAVPYMALYALGFSLPFLL
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LSFFITKMKWLRKHQLIIMKIGGVAMIVVGILLFFDWMTKIIIVLSSLFGDFRGF
HHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]