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The map label for this gene is spoVK [H]

Identifier: 52785745

GI number: 52785745

Start: 1943949

End: 1944914

Strand: Direct

Name: spoVK [H]

Synonym: BLi01989

Alternate gene names: 52785745

Gene position: 1943949-1944914 (Clockwise)

Preceding gene: 52785744

Following gene: 52785746

Centisome position: 46.04

GC content: 47.62

Gene sequence:

>966_bases
GTGTTGGAAAGGGCTGTTACTTATAAAAACAACGGACAAATCAATATCATATTGAACGGTCAAAAGCAGGTTTTGGCCAA
TTCAGAGGCTGAAGCCGAATATCAGGCCGCACTGCAAAAAAATGAAGCCAAACACAGCATTCTGAAAGAAATTGAAAGGG
AAATGAACACGCTGGTCGGAATGGAGGAAATGAAGCGCAATATCAAGGAAATCTACGCCTGGATTTTCGTTAATAAAAAG
CGCGAAGAACAAGGCCTTAAGGCCGGAAAACAGGCGCTTCACATGATGTTCAAAGGAAATCCGGGAACCGGAAAAACGAC
CGTCGCCAGGCTGATCGGCAGGCTTTTTTACGAAATGAATGTTCTCTCAAAAGGCCATCTGATCGAGGCGGAGCGCGCCG
ATCTCGTCGGTGAGTACATCGGCCATACGGCGCAAAAAACGAGGGATTTAATCAAAAAAGCGATGGGCGGAATCCTGTTC
ATCGATGAAGCCTATTCCCTTGCCAGAGGCGGAGAGAAAGACTTCGGCAAGGAGGCAATCGATACATTGGTCAAACATAT
GGAGGATAAGCGCAACGAATTCATTTTAATCCTCGCCGGATATTCGCGGGAAATGGATCATTTTCTTTCATTAAACCCGG
GCCTTCAGTCAAGGTTTCCGATCAGCATCGATTTTCCCGATTACTCAGTCAGCCAGCTGATGGACATTGCAAAACGGATG
ATGGCGGAAAGGGAATATCAGTTCAGCCCTGAGGCTGAATGGAAGCTGAAAGACCATCTGATGGCCGTCAAAAGTACGGT
CAGCCCCGCGAAGTTCAGCAATGGCCGTTTCGTCCGCAACCTGATCGAAAAATCCATCCGGTCGCAGGCGATGAGACTGC
TGATGGGAGACTGCTACTTAAAGAATGACTTGATAACCATCAAAAGCCAGGATCTCGACTTGAAGGAAGACGCGCCGCAC
GTATAA

Upstream 100 bases:

>100_bases
CGTTCTTGTCAAAAAGCATTGGATTGTGCAGTCATGTGGGCGTCTGTCACGGCATAAGCGCGCCATGAATAGGATATAAA
GAGAGAATGGTGAGGTGAGT

Downstream 100 bases:

>100_bases
TGGCGCGTTCTTTTTTTATTTTCGAGGATTTCTGGCAACCGCTCCCTTCGTTTGTTATGATAGTACTGCTTATTGACTAA
CGTTAAGAAAGGAACATGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLERAVTYKNNGQINIILNGQKQVLANSEAEAEYQAALQKNEAKHSILKEIEREMNTLVGMEEMKRNIKEIYAWIFVNKK
REEQGLKAGKQALHMMFKGNPGTGKTTVARLIGRLFYEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKAMGGILF
IDEAYSLARGGEKDFGKEAIDTLVKHMEDKRNEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVSQLMDIAKRM
MAEREYQFSPEAEWKLKDHLMAVKSTVSPAKFSNGRFVRNLIEKSIRSQAMRLLMGDCYLKNDLITIKSQDLDLKEDAPH
V

Sequences:

>Translated_321_residues
MLERAVTYKNNGQINIILNGQKQVLANSEAEAEYQAALQKNEAKHSILKEIEREMNTLVGMEEMKRNIKEIYAWIFVNKK
REEQGLKAGKQALHMMFKGNPGTGKTTVARLIGRLFYEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKAMGGILF
IDEAYSLARGGEKDFGKEAIDTLVKHMEDKRNEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVSQLMDIAKRM
MAEREYQFSPEAEWKLKDHLMAVKSTVSPAKFSNGRFVRNLIEKSIRSQAMRLLMGDCYLKNDLITIKSQDLDLKEDAPH
V
>Mature_321_residues
MLERAVTYKNNGQINIILNGQKQVLANSEAEAEYQAALQKNEAKHSILKEIEREMNTLVGMEEMKRNIKEIYAWIFVNKK
REEQGLKAGKQALHMMFKGNPGTGKTTVARLIGRLFYEMNVLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKAMGGILF
IDEAYSLARGGEKDFGKEAIDTLVKHMEDKRNEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVSQLMDIAKRM
MAEREYQFSPEAEWKLKDHLMAVKSTVSPAKFSNGRFVRNLIEKSIRSQAMRLLMGDCYLKNDLITIKSQDLDLKEDAPH
V

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR014232 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36665; Mature: 36665

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERAVTYKNNGQINIILNGQKQVLANSEAEAEYQAALQKNEAKHSILKEIEREMNTLVG
CCCCCEEECCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEEMKRNIKEIYAWIFVNKKREEQGLKAGKQALHMMFKGNPGTGKTTVARLIGRLFYEMN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKAMGGILFIDEAYSLARGGEKDFGKEAI
HCCCCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCCCCCHHHH
DTLVKHMEDKRNEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVSQLMDIAKRM
HHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
MAEREYQFSPEAEWKLKDHLMAVKSTVSPAKFSNGRFVRNLIEKSIRSQAMRLLMGDCYL
HHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
KNDLITIKSQDLDLKEDAPHV
CCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MLERAVTYKNNGQINIILNGQKQVLANSEAEAEYQAALQKNEAKHSILKEIEREMNTLVG
CCCCCEEECCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEEMKRNIKEIYAWIFVNKKREEQGLKAGKQALHMMFKGNPGTGKTTVARLIGRLFYEMN
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLSKGHLIEAERADLVGEYIGHTAQKTRDLIKKAMGGILFIDEAYSLARGGEKDFGKEAI
HCCCCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCCCCCHHHH
DTLVKHMEDKRNEFILILAGYSREMDHFLSLNPGLQSRFPISIDFPDYSVSQLMDIAKRM
HHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
MAEREYQFSPEAEWKLKDHLMAVKSTVSPAKFSNGRFVRNLIEKSIRSQAMRLLMGDCYL
HHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
KNDLITIKSQDLDLKEDAPHV
CCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1787791; 9384377 [H]