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The map label for this gene is nrdF [H]

Identifier: 52785724

GI number: 52785724

Start: 1923154

End: 1924131

Strand: Direct

Name: nrdF [H]

Synonym: BLi01967

Alternate gene names: 52785724

Gene position: 1923154-1924131 (Clockwise)

Preceding gene: 52785723

Following gene: 52785725

Centisome position: 45.54

GC content: 44.79

Gene sequence:

>978_bases
GTGACGAAAATTTACGATGCAGCAAACTGGTCAAAGCATGAAGATGATTTTACCCAAATGTTTTACAACCAAAATGTAAA
GCAGTTTTGGCTTCCGGAAGAGATTGCGCTTAATGGAGATCTTCTGACATGGAAGTACTTGGGTAAAAATGAACAGGACA
CATACATGAAGGTGCTCGCGGGGCTGACGCTTCTCGATACAGAGCAGGGGAACACGGGAATGCCCCTTGTTGCTGAGCAT
GTGGAAGGGCATCAGCGCAAAGCGGTGCTGAATTTCATGGCGATGATGGAAAACGCGGTCCACGCCAAGTCCTATTCAAA
CATTTTCATGACGCTGGCCCCGACAGAGACGATCAACGAAGTCTTTGAATGGGTCAAACAAAACAAATACCTGCAGAAAA
AAGCTCAGATCATTGTCGGGCTCTATGAAAAAATCCGCCAGGGCGATAAAATCTCGCTGTTTAAAGCGATGGTCGCATCC
GTTTATTTAGAAAGCTTCCTGTTCTACAGCGGCTTCTACTACCCGCTTTATTTTTACGGACAGGGCAAGCTGATGCAAAG
CGGCGAAATCATCAACCTGATCTTGCGTGATGAAGCGATTCACGGCGTCTATGTCGGCCTGCTCGCTCAGGAGATTTACA
ATCAGCAGACGCCGGAGAAAAAAGAAGAGCTGTATGCATTTTCCATTGATCTATTGAAAGAGCTTTATGAAAATGAGCTT
GAATATACAGAAGACCTGTACGATCAAGTCGGCCTTTCACACGACGTGAAGAAGTTCATCCGCTACAATGCCAACAAAGC
GCTGATGAACCTTGGCTTTGAAGCTTATTTTGAAGAAGAAGAGATCAATCCGATCGTGTTGAACGGGTTGAATACGAAAA
CGAAGTCACACGACTTCTTCTCAATGAAAGGGAACGGCTACAAAAAAGCAACAGTTGAACCGTTAAAAGACGACGACTTT
TACTTTGACGATAAGTAA

Upstream 100 bases:

>100_bases
ACCATAAAGGAATCAAAACACTTTACTATGCAAGAACGAAGGATACAGGGCAAGAAGGCTGCCTTTCTTGTGTCGTTTGA
TTAAAGGAGAGTATGCGAAA

Downstream 100 bases:

>100_bases
GCCGGGCTAAAAGGGCGCGCCAGCGCCCAAGCCCTGCCCTTCAGCTATTGATACACGGCAAAATGAGAGCAGAACGAATC
TGCTCTTTTCACTTTGAGGA

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPLVAEH
VEGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINEVFEWVKQNKYLQKKAQIIVGLYEKIRQGDKISLFKAMVAS
VYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYVGLLAQEIYNQQTPEKKEELYAFSIDLLKELYENEL
EYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFEAYFEEEEINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLKDDDF
YFDDK

Sequences:

>Translated_325_residues
MTKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPLVAEH
VEGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINEVFEWVKQNKYLQKKAQIIVGLYEKIRQGDKISLFKAMVAS
VYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYVGLLAQEIYNQQTPEKKEELYAFSIDLLKELYENEL
EYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFEAYFEEEEINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLKDDDF
YFDDK
>Mature_324_residues
TKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPLVAEHV
EGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINEVFEWVKQNKYLQKKAQIIVGLYEKIRQGDKISLFKAMVASV
YLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYVGLLAQEIYNQQTPEKKEELYAFSIDLLKELYENELE
YTEDLYDQVGLSHDVKKFIRYNANKALMNLGFEAYFEEEEINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLKDDDFY
FDDK

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI42544136, Length=298, Percent_Identity=24.1610738255034, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI289177074, Length=310, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789031, Length=319, Percent_Identity=44.2006269592476, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1788567, Length=313, Percent_Identity=21.405750798722, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17551968, Length=307, Percent_Identity=24.4299674267101, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 37897; Mature: 37765

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLA
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCHHHEECCCEEEEEECCCCCHHHHHHHHH
GLTLLDTEQGNTGMPLVAEHVEGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINE
CCCEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
VFEWVKQNKYLQKKAQIIVGLYEKIRQGDKISLFKAMVASVYLESFLFYSGFYYPLYFYG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
QGKLMQSGEIINLILRDEAIHGVYVGLLAQEIYNQQTPEKKEELYAFSIDLLKELYENEL
CCCEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
EYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFEAYFEEEEINPIVLNGLNTKTKSHDFF
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCHHHEECCCCCCEEEEECCCCCCCCCCEE
SMKGNGYKKATVEPLKDDDFYFDDK
EECCCCEECCCCCCCCCCCCEECCC
>Mature Secondary Structure 
TKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLA
CCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCHHHEECCCEEEEEECCCCCHHHHHHHHH
GLTLLDTEQGNTGMPLVAEHVEGHQRKAVLNFMAMMENAVHAKSYSNIFMTLAPTETINE
CCCEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
VFEWVKQNKYLQKKAQIIVGLYEKIRQGDKISLFKAMVASVYLESFLFYSGFYYPLYFYG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
QGKLMQSGEIINLILRDEAIHGVYVGLLAQEIYNQQTPEKKEELYAFSIDLLKELYENEL
CCCEECCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
EYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFEAYFEEEEINPIVLNGLNTKTKSHDFF
HHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCHHHEECCCCCCEEEEECCCCCCCCCCEE
SMKGNGYKKATVEPLKDDDFYFDDK
EECCCCEECCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969495; 9384377 [H]