| Definition | Bacillus licheniformis ATCC 14580, complete genome. |
|---|---|
| Accession | NC_006322 |
| Length | 4,222,645 |
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The map label for this gene is fabG [H]
Identifier: 52785670
GI number: 52785670
Start: 1872430
End: 1873161
Strand: Direct
Name: fabG [H]
Synonym: BLi01911
Alternate gene names: 52785670
Gene position: 1872430-1873161 (Clockwise)
Preceding gene: 52785669
Following gene: 52785671
Centisome position: 44.34
GC content: 51.78
Gene sequence:
>732_bases ATGACAAAACTCGCTCTCATCACCGGCGCAAGCGGCGGAATCGGGCAAAGCATCAGCGAAAAGCTTGCGCAAAACGGGTA TGATCTTCTCCTCCATTATCATACAAATGAGAAGGCGGCCGCTTCACTTGCAGAAAGGCTGTCACATACATACGGCATTC ACGCTGAAATCATTCACGGCGACCTGTCCGACCCCGGAGGTGCAAAAACCGTTTCCGCTTCCATCGGCGGACGGGCGCTA GACGGCATCGTCTTGAACAGCGGACAAAGCTTCCGCGGGCTTGTGACAGATATGACCGATGAAGCTGTACAGGACATGGT GCAGCTCCATGTCTCAAGCCCGTTTCTATTAACGAGGAATCTGCTTCCGGCGATGATCAGGAAAAAGTCCGGCGCTATTG TAGCCGTCAGCTCTATTTGGGGTGAGACAGGGGCGTCGTGCGAAGTTTTATACAGCATGACAAAAGGCGCGCAAAATGTG TTTGTCAAAGCCCTTGCAAAAGAGCTTGCGCCGAGCGGCATCAGAGTCAACGCTGTTTCTCCGGGCGCTGTAAAAACAAA GATGATGAGCTCATTTTCAAAAGAGGAAGAAGAGATGATCGCCGATGAGATTCCGATGGGAAGGCTCGCCGAAGCCGAAG AGGTTGCAGACGCCGTCTTGTTTCTGCTCTCGGCGAAAGCATCTTATATCACGGGTCAAATTTTGTCAGTTAATGGCGGC TGGCATTGTTAA
Upstream 100 bases:
>100_bases TCCAAAATCATAAAGCAAGGTCTGAAAGTTCAGCGTGCAGGGATATTTCCGATGCACGCTGAACCTTTCTTCTTTTTTAA CGGAAAGGTGGAAATATGGT
Downstream 100 bases:
>100_bases AAACATGTATAGTTTACGATTCCCAAGAGAATAATAAGGCTGTAACTTCAAGAGAATGGAGGGGCCTGATATGTCCGTAC TGGATAATTGGGATCAGTGG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 243; Mature: 242
Protein sequence:
>243_residues MTKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHGDLSDPGGAKTVSASIGGRAL DGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRNLLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNV FVKALAKELAPSGIRVNAVSPGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG WHC
Sequences:
>Translated_243_residues MTKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHGDLSDPGGAKTVSASIGGRAL DGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRNLLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNV FVKALAKELAPSGIRVNAVSPGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG WHC >Mature_242_residues TKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHGDLSDPGGAKTVSASIGGRALD GIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRNLLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNVF VKALAKELAPSGIRVNAVSPGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGGW HC
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=32.2314049586777, Blast_Score=115, Evalue=2e-26, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=34.5381526104418, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=31.4285714285714, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=28.6307053941909, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=27.3469387755102, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503301, Length=206, Percent_Identity=30.0970873786408, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI66933014, Length=169, Percent_Identity=31.9526627218935, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI59889578, Length=170, Percent_Identity=33.5294117647059, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI226371731, Length=197, Percent_Identity=27.4111675126904, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.1044176706827, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=25.4901960784314, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=29.2307692307692, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=27.0833333333333, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=27.3743016759777, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=36.0655737704918, Blast_Score=143, Evalue=9e-36, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=35.1020408163265, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=36.4705882352941, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.4285714285714, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=25.5144032921811, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=26.9387755102041, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786812, Length=171, Percent_Identity=32.1637426900585, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=24.5833333333333, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1787526, Length=215, Percent_Identity=28.3720930232558, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=26.3681592039801, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=34.8178137651822, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=35.0806451612903, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=34.9397590361446, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=31.6872427983539, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=32.520325203252, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=32.1705426356589, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=30.2040816326531, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17536025, Length=247, Percent_Identity=28.3400809716599, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=32.183908045977, Blast_Score=84, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=31.4176245210728, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=27.9352226720648, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=27.9352226720648, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=31.1284046692607, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=30.7407407407407, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.2134831460674, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=28.9855072463768, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.4615384615385, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=30.2238805970149, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=29.0697674418605, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=29.0441176470588, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25152911, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508651, Length=259, Percent_Identity=27.7992277992278, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561272, Length=206, Percent_Identity=23.3009708737864, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=27.9693486590038, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=28.0769230769231, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=27.8388278388278, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=25.2830188679245, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=166, Percent_Identity=27.710843373494, Blast_Score=74, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6322067, Length=213, Percent_Identity=30.5164319248826, Blast_Score=67, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=29.6, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.9397590361446, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=34.1463414634146, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=33.6032388663968, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.5220883534137, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=32.5301204819277, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.6, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24644337, Length=116, Percent_Identity=39.6551724137931, Blast_Score=81, Evalue=5e-16, Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24584744, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=28.3422459893048, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=26.6094420600858, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 25575; Mature: 25443
Theoretical pI: Translated: 6.15; Mature: 6.15
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHG CCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC DLSDPGGAKTVSASIGGRALDGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRN CCCCCCCCEEEEECCCCCEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH LLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNVFVKALAKELAPSGIRVNAVS HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECC PGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEEECCC WHC CCC >Mature Secondary Structure TKLALITGASGGIGQSISEKLAQNGYDLLLHYHTNEKAAASLAERLSHTYGIHAEIIHG CEEEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC DLSDPGGAKTVSASIGGRALDGIVLNSGQSFRGLVTDMTDEAVQDMVQLHVSSPFLLTRN CCCCCCCCEEEEECCCCCEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH LLPAMIRKKSGAIVAVSSIWGETGASCEVLYSMTKGAQNVFVKALAKELAPSGIRVNAVS HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECC PGAVKTKMMSSFSKEEEEMIADEIPMGRLAEAEEVADAVLFLLSAKASYITGQILSVNGG CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEEECCC WHC CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]