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The map label for this gene is spoIIIE [H]

Identifier: 52785665

GI number: 52785665

Start: 1865093

End: 1867438

Strand: Direct

Name: spoIIIE [H]

Synonym: BLi01906

Alternate gene names: 52785665

Gene position: 1865093-1867438 (Clockwise)

Preceding gene: 52785664

Following gene: 52785666

Centisome position: 44.17

GC content: 48.98

Gene sequence:

>2346_bases
ATGGCAAAAAGAAAACGAAAATCAACAAAGAAACAAAAACAAGGAAAAAAACGGATCCATCTTAAATTTGAATTGTACGG
ATTAATCTGTATCGCCATCTCGATTATTGCGGTTTTGCAGCTTGGCGTAGCAGGGCAAACGTTCATTTACATGTTCCGCT
TTTTCGCCGGTGAATGGTTCATCCTTTGCCTTCTCGGCCTCTTTTTAACGGGCTTGTCTTTATTTTGGAAAAAGAAAACA
CCCAGTTTTTTGACGAGGAGAAAAGCGGGCCTTTACTGCATCATTGCAAGCATGCTGCTTCTTTCACATGTCCAGCTGTT
TCAGCATTTGACCGAAAGGGGAATGGTTCAGTCTCCGAGCGTGATCCAAAATACGTGGGAGCTGTTTCTGATGGATGTAA
AAGGCGAGACAGGATCGCCTGATCTTGGAGGCGGAATGATTGGAGCCCTTTTATTCGCGGCGTCATATTTTCTGTTTGCA
TCTGCAGGATCTAAAATCATCGCCGTCTTCCTGATCTTGATCGGCCTTCTTTTGATTACGGATCGGTCGCTTCAGGAGAC
GCTGATCAAATGGATGACCCCGGTCGCCTCCTTCATGAAAAACCAGTGGCAGGCCTTTTTAGCAGATCTTAAACAATTGA
AAAACAGCTCGCCGAAAAAGAAATCCGGAAAAAAACAAAAGACGCAGAGAAAACCGAAAGTGTCTGAAGAGCCTGTACAA
GAAGCGGACCTTGATCCAGATCCGGTTATTCAATCAGAACCGATTATTTCAAGCTTTTCCGACCGTGATGAAAAGCCCGA
AGTTCAAGCTTACGAAGCTCCGGCGGCTCCTGCTGAACCTCCTGCTGAGCCCGAAATCGGTGAGGAAATGCAGGCCTCCG
GCGCGCCCGAAATCACGTTTACAGAGCTAGAAAACAAGGATTACCAGCTTCCGTCGATTCAATTGCTGGATGATCCGAAG
CACACAGGGCAGCAGGCGGATAAAAAGAATATTTACGACAATGCCAGGAAGCTGGAAAGGACGTTTCAAAGCTTCGGAGT
TAAGGCGAAAGTCACCCAGGTTCATCTCGGCCCGGCCGTCACGAAATATGAAGTCTATCCTGATGTGGGCGTCAAAGTCA
GCAAAATTGTCAACTTAAGTGACGACTTGGCTTTAGCGCTCGCGGCCAAGGATATCCGCATCGAAGCCCCGATCCCCGGA
AAATCGGCGATTGGAATCGAAGTGCCGAATGCGGAAGTGGCGATGGTTTCCTTGAAAGAAGTGCTTGAATCGAAACTGAA
TGACCGGCCGGATGCAAAGCTGATGATCGGCCTCGGCCGGAACATTTCCGGAGAAGCGGTATTGGCAGAGCTGAACAAAA
TGCCCCACCTTCTTGTTGCAGGAGCGACCGGAAGCGGGAAAAGCGTCTGTGTCAACGGGATCATTACAAGCATTTTGATG
AGGGCAAAGCCCCACGAAGTGAAGATGATGATGATTGATCCGAAAATGGTCGAGCTCAATGTCTACAACGGGATTCCGCA
TTTGCTCGCTCCCGTCGTGACAGACCCGAAAAAAGCATCGCAGGCTTTGAAGAAAGTCGTCAACGAAATGGAGCGGCGCT
ACGAATTGTTTTCTCACACGGGAACGAGAAATATCGAAGGGTATAACGACTATATTAAACGGATGAATGCCGCAGAAGAA
GCAAAGCAGCCGGAGCTTCCATACATCATTGTGATTGTGGACGAGCTTGCCGACCTGATGATGGTCGCTTCCTCTGATGT
TGAAGACTCGATCACAAGGCTTTCGCAAATGGCCAGGGCGGCGGGCATCCACCTGATCATTGCGACGCAGAGGCCTTCGG
TCGATGTTATCACAGGGGTCATTAAAGCCAACATTCCGTCAAGGATCGCTTTCAGCGTATCGTCTCAGACCGACTCCAGG
ACGATTCTTGATATGGGAGGCGCTGAAAAACTTCTCGGCAGAGGGGACATGCTGTTTCTCCCTGTCGGCGCCAATAAACC
GCTCCGCGTTCAAGGTGCCTTTCTGTCAGACGAAGAAGTTGAAAAAGTTGTCGATCACGTCATCAGCCAGCAAAAAGCCC
AATACCAAGAAGAAATGATTCCAGAAGAGACGCAGGAAACGGTCAGCGAAGTGACAGACGACCTTTATGACGAAGCGGTC
GCACTTGTGGTCAGCATGCAGACGGCTTCTGTATCCATGCTGCAAAGGAGATTCCGCATCGGCTATACAAGAGCGGCGCG
GCTTATCGATGCCATGGAAGAGCGGGGAATCGTCGGCCCATATGAAGGATCAAAACCCCGTGAAGTTCTCTTGTCAAAAG
AGCAATACGAAGAACTCTCTTCTTGA

Upstream 100 bases:

>100_bases
AATATGCTATAATAGGGGAATCCAGAGGAAAATCGCAGCCGAAAAAAGGCTGCTTTCTCTTTGTTTTTACATTTTTTAAC
ACGCAGTAAGGTGATGGAAC

Downstream 100 bases:

>100_bases
GAAGAGAGTTCTTGTTTAACATAATTTCATTATGTAAACTAAAAAACATCTATTTATTTATTTGACAAAACATGATATAG
TTATCCTCAATTAAAGATAA

Product: SpoIIIE

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MAKRKRKSTKKQKQGKKRIHLKFELYGLICIAISIIAVLQLGVAGQTFIYMFRFFAGEWFILCLLGLFLTGLSLFWKKKT
PSFLTRRKAGLYCIIASMLLLSHVQLFQHLTERGMVQSPSVIQNTWELFLMDVKGETGSPDLGGGMIGALLFAASYFLFA
SAGSKIIAVFLILIGLLLITDRSLQETLIKWMTPVASFMKNQWQAFLADLKQLKNSSPKKKSGKKQKTQRKPKVSEEPVQ
EADLDPDPVIQSEPIISSFSDRDEKPEVQAYEAPAAPAEPPAEPEIGEEMQASGAPEITFTELENKDYQLPSIQLLDDPK
HTGQQADKKNIYDNARKLERTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPG
KSAIGIEVPNAEVAMVSLKEVLESKLNDRPDAKLMIGLGRNISGEAVLAELNKMPHLLVAGATGSGKSVCVNGIITSILM
RAKPHEVKMMMIDPKMVELNVYNGIPHLLAPVVTDPKKASQALKKVVNEMERRYELFSHTGTRNIEGYNDYIKRMNAAEE
AKQPELPYIIVIVDELADLMMVASSDVEDSITRLSQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQTDSR
TILDMGGAEKLLGRGDMLFLPVGANKPLRVQGAFLSDEEVEKVVDHVISQQKAQYQEEMIPEETQETVSEVTDDLYDEAV
ALVVSMQTASVSMLQRRFRIGYTRAARLIDAMEERGIVGPYEGSKPREVLLSKEQYEELSS

Sequences:

>Translated_781_residues
MAKRKRKSTKKQKQGKKRIHLKFELYGLICIAISIIAVLQLGVAGQTFIYMFRFFAGEWFILCLLGLFLTGLSLFWKKKT
PSFLTRRKAGLYCIIASMLLLSHVQLFQHLTERGMVQSPSVIQNTWELFLMDVKGETGSPDLGGGMIGALLFAASYFLFA
SAGSKIIAVFLILIGLLLITDRSLQETLIKWMTPVASFMKNQWQAFLADLKQLKNSSPKKKSGKKQKTQRKPKVSEEPVQ
EADLDPDPVIQSEPIISSFSDRDEKPEVQAYEAPAAPAEPPAEPEIGEEMQASGAPEITFTELENKDYQLPSIQLLDDPK
HTGQQADKKNIYDNARKLERTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPG
KSAIGIEVPNAEVAMVSLKEVLESKLNDRPDAKLMIGLGRNISGEAVLAELNKMPHLLVAGATGSGKSVCVNGIITSILM
RAKPHEVKMMMIDPKMVELNVYNGIPHLLAPVVTDPKKASQALKKVVNEMERRYELFSHTGTRNIEGYNDYIKRMNAAEE
AKQPELPYIIVIVDELADLMMVASSDVEDSITRLSQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQTDSR
TILDMGGAEKLLGRGDMLFLPVGANKPLRVQGAFLSDEEVEKVVDHVISQQKAQYQEEMIPEETQETVSEVTDDLYDEAV
ALVVSMQTASVSMLQRRFRIGYTRAARLIDAMEERGIVGPYEGSKPREVLLSKEQYEELSS
>Mature_780_residues
AKRKRKSTKKQKQGKKRIHLKFELYGLICIAISIIAVLQLGVAGQTFIYMFRFFAGEWFILCLLGLFLTGLSLFWKKKTP
SFLTRRKAGLYCIIASMLLLSHVQLFQHLTERGMVQSPSVIQNTWELFLMDVKGETGSPDLGGGMIGALLFAASYFLFAS
AGSKIIAVFLILIGLLLITDRSLQETLIKWMTPVASFMKNQWQAFLADLKQLKNSSPKKKSGKKQKTQRKPKVSEEPVQE
ADLDPDPVIQSEPIISSFSDRDEKPEVQAYEAPAAPAEPPAEPEIGEEMQASGAPEITFTELENKDYQLPSIQLLDDPKH
TGQQADKKNIYDNARKLERTFQSFGVKAKVTQVHLGPAVTKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGK
SAIGIEVPNAEVAMVSLKEVLESKLNDRPDAKLMIGLGRNISGEAVLAELNKMPHLLVAGATGSGKSVCVNGIITSILMR
AKPHEVKMMMIDPKMVELNVYNGIPHLLAPVVTDPKKASQALKKVVNEMERRYELFSHTGTRNIEGYNDYIKRMNAAEEA
KQPELPYIIVIVDELADLMMVASSDVEDSITRLSQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQTDSRT
ILDMGGAEKLLGRGDMLFLPVGANKPLRVQGAFLSDEEVEKVVDHVISQQKAQYQEEMIPEETQETVSEVTDDLYDEAVA
LVVSMQTASVSMLQRRFRIGYTRAARLIDAMEERGIVGPYEGSKPREVLLSKEQYEELSS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=485, Percent_Identity=49.0721649484536, Blast_Score=424, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 86479; Mature: 86347

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRKRKSTKKQKQGKKRIHLKFELYGLICIAISIIAVLQLGVAGQTFIYMFRFFAGEWF
CCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILCLLGLFLTGLSLFWKKKTPSFLTRRKAGLYCIIASMLLLSHVQLFQHLTERGMVQSPS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VIQNTWELFLMDVKGETGSPDLGGGMIGALLFAASYFLFASAGSKIIAVFLILIGLLLIT
HHHHCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DRSLQETLIKWMTPVASFMKNQWQAFLADLKQLKNSSPKKKSGKKQKTQRKPKVSEEPVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHH
EADLDPDPVIQSEPIISSFSDRDEKPEVQAYEAPAAPAEPPAEPEIGEEMQASGAPEITF
HCCCCCCCCCCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCEEE
TELENKDYQLPSIQLLDDPKHTGQQADKKNIYDNARKLERTFQSFGVKAKVTQVHLGPAV
EECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCE
TKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSAIGIEVPNAEVAMVSLKE
EEEEECCCCCCCHHHHHCCCCHHHHEEEECCEEEECCCCCCCEEEEECCCCHHHHHHHHH
VLESKLNDRPDAKLMIGLGRNISGEAVLAELNKMPHLLVAGATGSGKSVCVNGIITSILM
HHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
RAKPHEVKMMMIDPKMVELNVYNGIPHLLAPVVTDPKKASQALKKVVNEMERRYELFSHT
HCCCCCEEEEEECCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTRNIEGYNDYIKRMNAAEEAKQPELPYIIVIVDELADLMMVASSDVEDSITRLSQMARA
CCCCCCCHHHHHHHHCHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQTDSRTILDMGGAEKLLGRGDMLFL
CCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCHHHHHCCCCEEEE
PVGANKPLRVQGAFLSDEEVEKVVDHVISQQKAQYQEEMIPEETQETVSEVTDDLYDEAV
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ALVVSMQTASVSMLQRRFRIGYTRAARLIDAMEERGIVGPYEGSKPREVLLSKEQYEELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHC
S
C
>Mature Secondary Structure 
AKRKRKSTKKQKQGKKRIHLKFELYGLICIAISIIAVLQLGVAGQTFIYMFRFFAGEWF
CCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ILCLLGLFLTGLSLFWKKKTPSFLTRRKAGLYCIIASMLLLSHVQLFQHLTERGMVQSPS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VIQNTWELFLMDVKGETGSPDLGGGMIGALLFAASYFLFASAGSKIIAVFLILIGLLLIT
HHHHCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DRSLQETLIKWMTPVASFMKNQWQAFLADLKQLKNSSPKKKSGKKQKTQRKPKVSEEPVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHH
EADLDPDPVIQSEPIISSFSDRDEKPEVQAYEAPAAPAEPPAEPEIGEEMQASGAPEITF
HCCCCCCCCCCCCCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHCCCCCCEEE
TELENKDYQLPSIQLLDDPKHTGQQADKKNIYDNARKLERTFQSFGVKAKVTQVHLGPAV
EECCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCE
TKYEVYPDVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSAIGIEVPNAEVAMVSLKE
EEEEECCCCCCCHHHHHCCCCHHHHEEEECCEEEECCCCCCCEEEEECCCCHHHHHHHHH
VLESKLNDRPDAKLMIGLGRNISGEAVLAELNKMPHLLVAGATGSGKSVCVNGIITSILM
HHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH
RAKPHEVKMMMIDPKMVELNVYNGIPHLLAPVVTDPKKASQALKKVVNEMERRYELFSHT
HCCCCCEEEEEECCEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTRNIEGYNDYIKRMNAAEEAKQPELPYIIVIVDELADLMMVASSDVEDSITRLSQMARA
CCCCCCCHHHHHHHHCHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHH
AGIHLIIATQRPSVDVITGVIKANIPSRIAFSVSSQTDSRTILDMGGAEKLLGRGDMLFL
CCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCHHHHHCCCCEEEE
PVGANKPLRVQGAFLSDEEVEKVVDHVISQQKAQYQEEMIPEETQETVSEVTDDLYDEAV
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ALVVSMQTASVSMLQRRFRIGYTRAARLIDAMEERGIVGPYEGSKPREVLLSKEQYEELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]