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The map label for this gene is cheA [H]

Identifier: 52785623

GI number: 52785623

Start: 1818012

End: 1820033

Strand: Direct

Name: cheA [H]

Synonym: BLi01864

Alternate gene names: 52785623

Gene position: 1818012-1820033 (Clockwise)

Preceding gene: 52785622

Following gene: 52785624

Centisome position: 43.05

GC content: 47.92

Gene sequence:

>2022_bases
ATGGATATGAATCAATATTTAGACGTCTTTATTGAAGAAAGCAGAGAACATTTGCAAACCTGTAACGAAAAATTGCTCGA
ACTCGAAAAAAATCCGACAGACTTGCAGCTTGTCCATGATATTTTCAGAGCGGCTCATACCTTGAAAGGGATGAGCGCAA
CGATGGGCTATGAAGACATGGCTCATTTAACGCACAGTCTGGAAAACGTGCTGGATGCGATTCGAAATGAAGAAATGACC
ATCACGTCAGAGTGGATGGACGTCATGTTTGAAGCGCTCGATGACCTTGAAGCAATCGTCCTTTCGATCATCGAAGGCGG
CGACGGCAAAAGAGATGTTTCCGAAGTCTGCGCCAAGCTTGATGTGACAGGGGCAAACAAGGAGGCGGCAGCAGCGGCAG
AAGCGCCTGAAGCGGCGTCTTCCGAAACGAAATGGTCCTATGACGAATTTCAACGAACGGTCATCGCCGAAGCTGAGGAA
CAAGGCTTTAAATGTTTCGAAATCAAAGTTGCATTGAAAGAGGACTGTCTGTTGAAGGGCGTTCGGGTGTACATGGTATT
TGAGCAGCTGAACGAGGTCGGCGAAGTCGTTAAAACGATTCCGGAAACAGAAGTCCTTGAATCGGAGGATTTTGATTCCG
AATTCGTCATCTGCTTTTTAAGCAAACACGGAAAAGAAGAGATTTTCAACAAAATCAACGGCGTATCTGAAATTGAAAAA
ATAGAAGTGACCGAGCTGAAAAACGATTTTTCGGCACAAGAAGAAGCGAAGCCCGCCGCATCCGAAAAAGAAACCGCACC
GAAAGAGGCGGAGAAAAAACCGGCTAAGCAGCCGGACGGCAAAAAAGACGCGGCGAAACCTGCGGCAGGCGGCGGAACGA
AGACGATCCGCGTCAACATCGACCGCCTCGATTCATTAATGAACCTGTTTGAAGAGCTGGTCATTGACAGGGGGCGCTTA
GAGCAGATCGCCAAAGAGCTAGAACACAGCGAATTAACGGAAACCGTCGAACGGATGACTAGAATTTCAGGCGACCTGCA
GTCGATCATCCTCAATATGAGAATGGTTCCGGTAGAAACGGTGTTCAACCGATTCCCGCGCATGGTCCGCCAGCTGACAA
AAGAATTAAATAAAAAGATCGAGCTGTCGATTTTCGGAGCGGAAACAGAGCTTGACAGAACGGTAATAGACGAAATCGGC
GACCCGCTTGTCCACCTCTTGAGAAACAGCCTTGATCACGGGATCGAGGCGCCTGAAGTCAGGGTGAAAAACGGTAAACC
TGAAACCGGTCAAGTCCGCCTGAAAGCATACCACAGCGGTAACCATGTCTTTATCGAGGTGGAGGATGACGGCGCCGGCA
TCAACCGCAAAAAGGTGCTCGAAAAAGCGCTTGAGCGCAACGTCATTACTGAACGCGAAGCCGAAACGATCGAAGATCAT
GAAATCGACGCGCTCATTTTTGCGCCGGGATTCTCAACCGCAGATCAAATCTCGGATATTTCAGGACGCGGAGTCGGCTT
AGACGTTGTCAAAAGCAAGCTGGAATCGTTGGGCGGTTCTGTCAGCATCAAATCGAGCGAAGGCGAAGGTTCGCTTTTCT
CCATCCAGCTTCCGCTTACACTGTCGATCATTTCCGTGCTGTTAGTCAAACTTGAAAATGAAACGTTTGCGATTCCGATT
TCTTCTATTATAGAAACGGCTGTCATCGATAAGAAAGATATTCTTCAAACGCACGACCGCGAAGTGATCGATTTCAGGGG
CCATATCGTACCGGTGGTTTACCTGAAAGAACAGTTTAATGTTGAGGATTCTTCAGATGATCTTGATCAGCTTCACGTCA
TCGTCGTGAAAAAAGGAGACAAGCTGACGGCATTTGTTGTCGACTCCTTTATCGGCCAGCAGGAAGTCGTATTAAAATCA
CTCGGCGATTATTTAACAAACGTCTTTGCCATTTCCGGCGCGACGATTTTGGGAGACGGACAAGTAGCCCTGATCATCGA
CTGCAACGCCCTTATTAAATAG

Upstream 100 bases:

>100_bases
AATCGGTCATTAACAACGGGCTTGCAAACGACATCAAGCATGTTGATGAGATTGCCGCAGCCATTATGACGTATATGAAA
AAAGAGAGGGCGTGACTCAT

Downstream 100 bases:

>100_bases
AAAGCGAAAGGAGAGCGATCCTCTTGACCACACAGACTACCACCGGTGAGAAAATGATTGTGTTCAAAGTAAATCATAAA
GAGTATGCCATCTCTGTATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MDMNQYLDVFIEESREHLQTCNEKLLELEKNPTDLQLVHDIFRAAHTLKGMSATMGYEDMAHLTHSLENVLDAIRNEEMT
ITSEWMDVMFEALDDLEAIVLSIIEGGDGKRDVSEVCAKLDVTGANKEAAAAAEAPEAASSETKWSYDEFQRTVIAEAEE
QGFKCFEIKVALKEDCLLKGVRVYMVFEQLNEVGEVVKTIPETEVLESEDFDSEFVICFLSKHGKEEIFNKINGVSEIEK
IEVTELKNDFSAQEEAKPAASEKETAPKEAEKKPAKQPDGKKDAAKPAAGGGTKTIRVNIDRLDSLMNLFEELVIDRGRL
EQIAKELEHSELTETVERMTRISGDLQSIILNMRMVPVETVFNRFPRMVRQLTKELNKKIELSIFGAETELDRTVIDEIG
DPLVHLLRNSLDHGIEAPEVRVKNGKPETGQVRLKAYHSGNHVFIEVEDDGAGINRKKVLEKALERNVITEREAETIEDH
EIDALIFAPGFSTADQISDISGRGVGLDVVKSKLESLGGSVSIKSSEGEGSLFSIQLPLTLSIISVLLVKLENETFAIPI
SSIIETAVIDKKDILQTHDREVIDFRGHIVPVVYLKEQFNVEDSSDDLDQLHVIVVKKGDKLTAFVVDSFIGQQEVVLKS
LGDYLTNVFAISGATILGDGQVALIIDCNALIK

Sequences:

>Translated_673_residues
MDMNQYLDVFIEESREHLQTCNEKLLELEKNPTDLQLVHDIFRAAHTLKGMSATMGYEDMAHLTHSLENVLDAIRNEEMT
ITSEWMDVMFEALDDLEAIVLSIIEGGDGKRDVSEVCAKLDVTGANKEAAAAAEAPEAASSETKWSYDEFQRTVIAEAEE
QGFKCFEIKVALKEDCLLKGVRVYMVFEQLNEVGEVVKTIPETEVLESEDFDSEFVICFLSKHGKEEIFNKINGVSEIEK
IEVTELKNDFSAQEEAKPAASEKETAPKEAEKKPAKQPDGKKDAAKPAAGGGTKTIRVNIDRLDSLMNLFEELVIDRGRL
EQIAKELEHSELTETVERMTRISGDLQSIILNMRMVPVETVFNRFPRMVRQLTKELNKKIELSIFGAETELDRTVIDEIG
DPLVHLLRNSLDHGIEAPEVRVKNGKPETGQVRLKAYHSGNHVFIEVEDDGAGINRKKVLEKALERNVITEREAETIEDH
EIDALIFAPGFSTADQISDISGRGVGLDVVKSKLESLGGSVSIKSSEGEGSLFSIQLPLTLSIISVLLVKLENETFAIPI
SSIIETAVIDKKDILQTHDREVIDFRGHIVPVVYLKEQFNVEDSSDDLDQLHVIVVKKGDKLTAFVVDSFIGQQEVVLKS
LGDYLTNVFAISGATILGDGQVALIIDCNALIK
>Mature_673_residues
MDMNQYLDVFIEESREHLQTCNEKLLELEKNPTDLQLVHDIFRAAHTLKGMSATMGYEDMAHLTHSLENVLDAIRNEEMT
ITSEWMDVMFEALDDLEAIVLSIIEGGDGKRDVSEVCAKLDVTGANKEAAAAAEAPEAASSETKWSYDEFQRTVIAEAEE
QGFKCFEIKVALKEDCLLKGVRVYMVFEQLNEVGEVVKTIPETEVLESEDFDSEFVICFLSKHGKEEIFNKINGVSEIEK
IEVTELKNDFSAQEEAKPAASEKETAPKEAEKKPAKQPDGKKDAAKPAAGGGTKTIRVNIDRLDSLMNLFEELVIDRGRL
EQIAKELEHSELTETVERMTRISGDLQSIILNMRMVPVETVFNRFPRMVRQLTKELNKKIELSIFGAETELDRTVIDEIG
DPLVHLLRNSLDHGIEAPEVRVKNGKPETGQVRLKAYHSGNHVFIEVEDDGAGINRKKVLEKALERNVITEREAETIEDH
EIDALIFAPGFSTADQISDISGRGVGLDVVKSKLESLGGSVSIKSSEGEGSLFSIQLPLTLSIISVLLVKLENETFAIPI
SSIIETAVIDKKDILQTHDREVIDFRGHIVPVVYLKEQFNVEDSSDDLDQLHVIVVKKGDKLTAFVVDSFIGQQEVVLKS
LGDYLTNVFAISGATILGDGQVALIIDCNALIK

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=688, Percent_Identity=34.7383720930233, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74826; Mature: 74826

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNQYLDVFIEESREHLQTCNEKLLELEKNPTDLQLVHDIFRAAHTLKGMSATMGYEDM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHH
AHLTHSLENVLDAIRNEEMTITSEWMDVMFEALDDLEAIVLSIIEGGDGKRDVSEVCAKL
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
DVTGANKEAAAAAEAPEAASSETKWSYDEFQRTVIAEAEEQGFKCFEIKVALKEDCLLKG
CCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHH
VRVYMVFEQLNEVGEVVKTIPETEVLESEDFDSEFVICFLSKHGKEEIFNKINGVSEIEK
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHH
IEVTELKNDFSAQEEAKPAASEKETAPKEAEKKPAKQPDGKKDAAKPAAGGGTKTIRVNI
HHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEH
DRLDSLMNLFEELVIDRGRLEQIAKELEHSELTETVERMTRISGDLQSIILNMRMVPVET
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHH
VFNRFPRMVRQLTKELNKKIELSIFGAETELDRTVIDEIGDPLVHLLRNSLDHGIEAPEV
HHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCE
RVKNGKPETGQVRLKAYHSGNHVFIEVEDDGAGINRKKVLEKALERNVITEREAETIEDH
EECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCC
EIDALIFAPGFSTADQISDISGRGVGLDVVKSKLESLGGSVSIKSSEGEGSLFSIQLPLT
CCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCHH
LSIISVLLVKLENETFAIPISSIIETAVIDKKDILQTHDREVIDFRGHIVPVVYLKEQFN
HHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHHHCCCHHEECCCCEEEEEEEECCCC
VEDSSDDLDQLHVIVVKKGDKLTAFVVDSFIGQQEVVLKSLGDYLTNVFAISGATILGDG
CCCCCCCCCCEEEEEEECCCCEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEECC
QVALIIDCNALIK
CEEEEEECHHHCC
>Mature Secondary Structure
MDMNQYLDVFIEESREHLQTCNEKLLELEKNPTDLQLVHDIFRAAHTLKGMSATMGYEDM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHCCHHHH
AHLTHSLENVLDAIRNEEMTITSEWMDVMFEALDDLEAIVLSIIEGGDGKRDVSEVCAKL
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
DVTGANKEAAAAAEAPEAASSETKWSYDEFQRTVIAEAEEQGFKCFEIKVALKEDCLLKG
CCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHH
VRVYMVFEQLNEVGEVVKTIPETEVLESEDFDSEFVICFLSKHGKEEIFNKINGVSEIEK
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHH
IEVTELKNDFSAQEEAKPAASEKETAPKEAEKKPAKQPDGKKDAAKPAAGGGTKTIRVNI
HHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEH
DRLDSLMNLFEELVIDRGRLEQIAKELEHSELTETVERMTRISGDLQSIILNMRMVPVET
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHH
VFNRFPRMVRQLTKELNKKIELSIFGAETELDRTVIDEIGDPLVHLLRNSLDHGIEAPEV
HHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCE
RVKNGKPETGQVRLKAYHSGNHVFIEVEDDGAGINRKKVLEKALERNVITEREAETIEDH
EECCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCC
EIDALIFAPGFSTADQISDISGRGVGLDVVKSKLESLGGSVSIKSSEGEGSLFSIQLPLT
CCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCHH
LSIISVLLVKLENETFAIPISSIIETAVIDKKDILQTHDREVIDFRGHIVPVVYLKEQFN
HHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHHHCCCHHEECCCCEEEEEEEECCCC
VEDSSDDLDQLHVIVVKKGDKLTAFVVDSFIGQQEVVLKSLGDYLTNVFAISGATILGDG
CCCCCCCCCCEEEEEEECCCCEEHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEECC
QVALIIDCNALIK
CEEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1938941; 9384377 [H]