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The map label for this gene is xerC

Identifier: 52785593

GI number: 52785593

Start: 1792420

End: 1793334

Strand: Direct

Name: xerC

Synonym: BLi01834

Alternate gene names: 52785593

Gene position: 1792420-1793334 (Clockwise)

Preceding gene: 52785592

Following gene: 52785594

Centisome position: 42.45

GC content: 42.19

Gene sequence:

>915_bases
ATGGCAAATGTTAAGAATTTTTTAACTTTATTCATTGAATATTTACAAATAGAAAAGAATTATTCAAAATATACAATTGT
GGGTTACATTTCTTCCATTGAAGACTTTGAACGCTTTTTACACGTTCAGGGCATAAAGGGTTTTGAAGACGTGACTTATC
CGGATGTGAGAATTTTCTTGACGGAAGCGCATGAAAAAGGGCTCACTCGCAGGACGATCAGCAAGAAAATTTCGGCTCTG
CGTAGCTTCTATAAATTTTTATTAAGGGAAAAGCTGGTAAAAGAAAACCCGTTTCTGCTTGTCAGTCTCCCGAAACAGGA
TAAGCGGATTCCGAAGTTTTTATATGAAAAGGAACTTGAAGAACTGTTTGAGGTTTCGGATTTGAGTACACCGCTCGGCC
AAAGAAATCAGGCGCTCCTGGAATTTCTCTACGCGACAGGCATGCGGGTAAGCGAACTTTGCAGCCTGAAGGAATCTGAT
TTGGATCTGTTTTTAGATACGGTTTTGGTCCACGGGAAAGGCAGGAAGCAAAGGTATATTCCATTTGGTTCATTCGCCCG
GGAGGCTTTGGATCTGTATTTGCAAAATGGAAGACGCATCCTTCTGTTAAAAGCGAAAGAGCCCTGCCCTTTTATTTTTT
TGAATCAAAGGGGCGGGCCCTTAACCCCGAGGGGGGTTCGTTACATTTTGGGAGAACTGGTCAAGAAGACTTCGGGTACA
TTACATATACATCCGCATATGCTCCGCCATACATTTGCCACCCATTTGTTAAATGAGGGTGCGGATCTGAGGAGCGTTCA
GGAACTGCTTGGGCATTCAAATCTTTCTTCAACCCAGGTGTATACGCATGTATCTAAAGATATGCTCAGAAAGACATATA
TGTCTCATCACCCTCGGGCACATAAAGGGAAATAA

Upstream 100 bases:

>100_bases
GGAGACAATTCGAAATATTTCGAAAACGCTATAGTTATTCATTGCCAGATGAACTTGTTATGTGATAACATTTAAAAGCC
CTTTTCGAAGAGGTGTAATG

Downstream 100 bases:

>100_bases
AGGAGGTTCTTTTATGTCATCTTTTCACGCAACGACGATATTTGCCGTCCAGCACAACGGAAAAAGCGCGATGGCGGGAG
ACGGCCAGGTTACGTTCGGT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MANVKNFLTLFIEYLQIEKNYSKYTIVGYISSIEDFERFLHVQGIKGFEDVTYPDVRIFLTEAHEKGLTRRTISKKISAL
RSFYKFLLREKLVKENPFLLVSLPKQDKRIPKFLYEKELEELFEVSDLSTPLGQRNQALLEFLYATGMRVSELCSLKESD
LDLFLDTVLVHGKGRKQRYIPFGSFAREALDLYLQNGRRILLLKAKEPCPFIFLNQRGGPLTPRGVRYILGELVKKTSGT
LHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQVYTHVSKDMLRKTYMSHHPRAHKGK

Sequences:

>Translated_304_residues
MANVKNFLTLFIEYLQIEKNYSKYTIVGYISSIEDFERFLHVQGIKGFEDVTYPDVRIFLTEAHEKGLTRRTISKKISAL
RSFYKFLLREKLVKENPFLLVSLPKQDKRIPKFLYEKELEELFEVSDLSTPLGQRNQALLEFLYATGMRVSELCSLKESD
LDLFLDTVLVHGKGRKQRYIPFGSFAREALDLYLQNGRRILLLKAKEPCPFIFLNQRGGPLTPRGVRYILGELVKKTSGT
LHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQVYTHVSKDMLRKTYMSHHPRAHKGK
>Mature_303_residues
ANVKNFLTLFIEYLQIEKNYSKYTIVGYISSIEDFERFLHVQGIKGFEDVTYPDVRIFLTEAHEKGLTRRTISKKISALR
SFYKFLLREKLVKENPFLLVSLPKQDKRIPKFLYEKELEELFEVSDLSTPLGQRNQALLEFLYATGMRVSELCSLKESDL
DLFLDTVLVHGKGRKQRYIPFGSFAREALDLYLQNGRRILLLKAKEPCPFIFLNQRGGPLTPRGVRYILGELVKKTSGTL
HIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQVYTHVSKDMLRKTYMSHHPRAHKGK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=304, Percent_Identity=35.5263157894737, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789261, Length=291, Percent_Identity=39.1752577319588, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1790767, Length=181, Percent_Identity=30.939226519337, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790768, Length=172, Percent_Identity=29.6511627906977, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_BACLD (Q65JN5)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079007.1
- RefSeq:   YP_091422.1
- HSSP:   P0A8P8
- ProteinModelPortal:   Q65JN5
- SMR:   Q65JN5
- STRING:   Q65JN5
- EnsemblBacteria:   EBBACT00000054285
- EnsemblBacteria:   EBBACT00000061808
- GeneID:   3031007
- GeneID:   3099518
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01834
- KEGG:   bli:BL01279
- NMPDR:   fig|279010.5.peg.2537
- eggNOG:   COG4974
- GeneTree:   EBGT00070000031883
- HOGENOM:   HBG727654
- OMA:   GIRYCLT
- ProtClustDB:   PRK00236
- BioCyc:   BLIC279010-1:BLI01834-MONOMER
- BioCyc:   BLIC279010:BL01279-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02224

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35257; Mature: 35125

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 173-173 ACT_SITE 246-246 ACT_SITE 249-249 ACT_SITE 272-272 ACT_SITE 281-281

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVKNFLTLFIEYLQIEKNYSKYTIVGYISSIEDFERFLHVQGIKGFEDVTYPDVRIFL
CCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
TEAHEKGLTRRTISKKISALRSFYKFLLREKLVKENPFLLVSLPKQDKRIPKFLYEKELE
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
ELFEVSDLSTPLGQRNQALLEFLYATGMRVSELCSLKESDLDLFLDTVLVHGKGRKQRYI
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
PFGSFAREALDLYLQNGRRILLLKAKEPCPFIFLNQRGGPLTPRGVRYILGELVKKTSGT
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
LHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQVYTHVSKDMLRKTYMSHHPRA
EEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
HKGK
CCCC
>Mature Secondary Structure 
ANVKNFLTLFIEYLQIEKNYSKYTIVGYISSIEDFERFLHVQGIKGFEDVTYPDVRIFL
CCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
TEAHEKGLTRRTISKKISALRSFYKFLLREKLVKENPFLLVSLPKQDKRIPKFLYEKELE
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
ELFEVSDLSTPLGQRNQALLEFLYATGMRVSELCSLKESDLDLFLDTVLVHGKGRKQRYI
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
PFGSFAREALDLYLQNGRRILLLKAKEPCPFIFLNQRGGPLTPRGVRYILGELVKKTSGT
CCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCE
LHIHPHMLRHTFATHLLNEGADLRSVQELLGHSNLSSTQVYTHVSKDMLRKTYMSHHPRA
EEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
HKGK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA