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The map label for this gene is sucD [H]

Identifier: 52785589

GI number: 52785589

Start: 1786775

End: 1787677

Strand: Direct

Name: sucD [H]

Synonym: BLi01830

Alternate gene names: 52785589

Gene position: 1786775-1787677 (Clockwise)

Preceding gene: 52785588

Following gene: 52785590

Centisome position: 42.31

GC content: 50.06

Gene sequence:

>903_bases
ATGAGTGTATTTATTAATAAAGACACAAAAGTCATTGTTCAGGGGATAACGGGTTCAACCGCTTTGTTTCACACAAAGCA
GATGCTTGAATACGGAACGAAAATTGTCGGCGGAGTCACACCGGGCAAAGGCGGAACAGAGGTCGAAGGGGTGCCTGTGT
TCAATACGGTCGAAGAGGCTGTAAAGCAGACCGGGGCAAATGCGTCTGTCATTTACGTTCCTGCGGCTTTTGCGGCCGAT
GCGATTATGGAAGCGACAGATGCTGAGCTTGATCTTGTCATCTGCATTACTGAGCATATTCCGGTGCTTGATATGGTAAA
AGTCAAAAGGTATATGGAAGGCAAGAAAACGAGACTCATCGGTCCGAACTGCCCGGGAGTCATTACGCCTGAGGAATGCA
AAATCGGGATCATGCCCGGATATATCCATAAAAAAGGCCATGTCGGCGTTGTGTCGCGTTCAGGAACCCTTACATATGAA
GCGGTTCATCAGCTTTCCGAAGCAGGAGTCGGCCAGTCGACAGCAGTGGGCATCGGCGGAGACCCCGTCAACGGCACAAA
CTTCATCGATGTGCTGAAGGCTTTTAATGAAGATCCTGATACACATGCGGTGATCATGATCGGCGAAATCGGCGGAACAG
CTGAAGAGGAAGCGGCTGAATGGGTGAAAGCCAACATGACCAAACCTGTCGTCGGTTTCATCGGAGGAAAGACAGCGCCT
CCGGGCAAGCGCATGGGGCATGCGGGCGCCATCATTTCCGGAGGAAAAGGCACGGCGGACGAAAAGATCAAAACGATGAA
TGCCTGCGGAATCGAAGTGGCTGAAACGCCTTCTGTCATGGGAGAAACATTGATTAAAGTGCTGAAGGAAAAAGGTCTTT
ACGAAACGTGTAAAACACACTGA

Upstream 100 bases:

>100_bases
CCTCGATGATTCAGGACTCAATATTACGTCTGCGGAATCAATGGCTGACGGCGCGCAGAAAATCGTATCCTTAGTGAAGT
AAGAAAGGCAGGGGACCAAA

Downstream 100 bases:

>100_bases
TGATTAAAAAGAGCGGGAATAGTCCGATTGGTCTATTCCTGCTTTTTCATAACTGGTTATATCGTTTAGTACTTTCAGAT
TGTTTTGTTTTAAAAATTTT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSVFINKDTKVIVQGITGSTALFHTKQMLEYGTKIVGGVTPGKGGTEVEGVPVFNTVEEAVKQTGANASVIYVPAAFAAD
AIMEATDAELDLVICITEHIPVLDMVKVKRYMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYE
AVHQLSEAGVGQSTAVGIGGDPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGKTAP
PGKRMGHAGAIISGGKGTADEKIKTMNACGIEVAETPSVMGETLIKVLKEKGLYETCKTH

Sequences:

>Translated_300_residues
MSVFINKDTKVIVQGITGSTALFHTKQMLEYGTKIVGGVTPGKGGTEVEGVPVFNTVEEAVKQTGANASVIYVPAAFAAD
AIMEATDAELDLVICITEHIPVLDMVKVKRYMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYE
AVHQLSEAGVGQSTAVGIGGDPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGKTAP
PGKRMGHAGAIISGGKGTADEKIKTMNACGIEVAETPSVMGETLIKVLKEKGLYETCKTH
>Mature_299_residues
SVFINKDTKVIVQGITGSTALFHTKQMLEYGTKIVGGVTPGKGGTEVEGVPVFNTVEEAVKQTGANASVIYVPAAFAADA
IMEATDAELDLVICITEHIPVLDMVKVKRYMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYEA
VHQLSEAGVGQSTAVGIGGDPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGKTAPP
GKRMGHAGAIISGGKGTADEKIKTMNACGIEVAETPSVMGETLIKVLKEKGLYETCKTH

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=296, Percent_Identity=61.1486486486487, Blast_Score=308, Evalue=3e-84,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=28.3464566929134, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=28.3464566929134, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=64.3598615916955, Blast_Score=374, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=63.1578947368421, Blast_Score=345, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=59.5890410958904, Blast_Score=330, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=25.5905511811024, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=293, Percent_Identity=47.4402730375427, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21356559, Length=287, Percent_Identity=55.7491289198606, Blast_Score=330, Evalue=7e-91,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=58.4192439862543, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI281363477, Length=316, Percent_Identity=26.5822784810127, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363475, Length=316, Percent_Identity=26.5822784810127, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363473, Length=316, Percent_Identity=26.5822784810127, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31451; Mature: 31320

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFINKDTKVIVQGITGSTALFHTKQMLEYGTKIVGGVTPGKGGTEVEGVPVFNTVEEA
CEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHH
VKQTGANASVIYVPAAFAADAIMEATDAELDLVICITEHIPVLDMVKVKRYMEGKKTRLI
HHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLSEAGVGQSTAVGIGG
CCCCCCCCCCCCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCC
DPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGKTAP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTADEKIKTMNACGIEVAETPSVMGETLIKVLKEKGLYETCKTH
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
SVFINKDTKVIVQGITGSTALFHTKQMLEYGTKIVGGVTPGKGGTEVEGVPVFNTVEEA
EEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHH
VKQTGANASVIYVPAAFAADAIMEATDAELDLVICITEHIPVLDMVKVKRYMEGKKTRLI
HHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLSEAGVGQSTAVGIGG
CCCCCCCCCCCCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEECCC
DPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGKTAP
CCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTADEKIKTMNACGIEVAETPSVMGETLIKVLKEKGLYETCKTH
CCCCCCCCCEEEECCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]