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The map label for this gene is sucC

Identifier: 52785588

GI number: 52785588

Start: 1785596

End: 1786756

Strand: Direct

Name: sucC

Synonym: BLi01829

Alternate gene names: 52785588

Gene position: 1785596-1786756 (Clockwise)

Preceding gene: 52785587

Following gene: 52785589

Centisome position: 42.29

GC content: 48.41

Gene sequence:

>1161_bases
ATGAATATCCATGAGTACCAAGGGAAAGAAGTACTCAGAAAATACGGAGTGGCTGTTCCGGAAGGTAAAGTGGCATTTAC
AGCAGATGAAGCGGTCAAAGCAGCGGAAGCGCTGTCCAGCTCGGTTTATGTCGTGAAAGCTCAAATTCACGCCGGCGGAC
GCGGTAAAGCTGGCGGGGTTAAAATTGCAAAATCAAAAGAAGAAGTCAAAGCCTATGCGGAAGAATTGTTGGGAAAGACG
CTTGTCACTCACCAGACGGGTCCCGACGGCCAACAAATAAAACGCTTACTTATTGAAGAAGGCTGCGATATCAAAAAAGA
ATACTATGTCGGCCTAGTTCTCGACAGGGCGACTTCACGCATCGTGCTGATGGCCTCTGAAGAAGGCGGCACGGAAATTG
AAGAAGTCGCTGAAAAAACACCGGAAAAAATCGTCAAAGAAGTGATCGATCCGGCTGTCGGACTGCAGAGCTACCAGGCG
AGAAAAATCGCCTTCGCCATCAATATTCCGAAAGAGCTTGTCGGCCAGGCCGTTAAGTTTATGATGGGGCTGTACAAGGC
GTTTACTGAAAAAGACTGTTCCATTGCTGAAATCAATCCGCTCGTCGTCACAGGGGACGGAAAAGTCATGGCCCTTGACG
CCAAGCTGAACTTTGACAGCAATGCGCTATACAGACAAAAAGACATCTTGGAGTACAGAGATCTCGATGAAGAAGATCCG
AAGGAAATCGAAGCATCCAAGTATGATTTAAGCTATATTTCGCTCGATGGAAACATCGGCTGCATGGTCAACGGAGCGGG
GCTTGCGATGTCGACCATGGACATTATCAAGCACTACGGAGGGGAACCGGCCAACTTCCTTGACGTTGGAGGCGGCGCGA
CAGCCGAAAAGGTAACGGAAGCGTTCAAGATCATTTTGTCTGATCAAAACGTCAAAGGGATCTTTGTCAATATTTTCGGC
GGCATCATGAAATGCGACGTCATTGCAGAAGGCGTTGTTGAAGCGACAAAACAAGTCGGTCTGACATTGCCGCTTGTCGT
TCGCCTTGAAGGCACCAATGTCGATCTCGGCAAGAAGATCCTCGATGATTCAGGACTCAATATTACGTCTGCGGAATCAA
TGGCTGACGGCGCGCAGAAAATCGTATCCTTAGTGAAGTAA

Upstream 100 bases:

>100_bases
TACGATTTCTCATCGAAACCTAGACAATCGATCTATGATTATATAAAATGAAAGCGCAGTCTATTTTTATTTTTGCTACA
TAAGTTAGGAGGATGGGAAA

Downstream 100 bases:

>100_bases
GAAAGGCAGGGGACCAAAATGAGTGTATTTATTAATAAAGACACAAAAGTCATTGTTCAGGGGATAACGGGTTCAACCGC
TTTGTTTCACACAAAGCAGA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQGKEVLRKYGVAVPEGKVAFTADEAVKAAEALSSSVYVVKAQIHAGGRGKAGGVKIAKSKEEVKAYAEELLGKT
LVTHQTGPDGQQIKRLLIEEGCDIKKEYYVGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIVKEVIDPAVGLQSYQA
RKIAFAINIPKELVGQAVKFMMGLYKAFTEKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRQKDILEYRDLDEEDP
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFG
GIMKCDVIAEGVVEATKQVGLTLPLVVRLEGTNVDLGKKILDDSGLNITSAESMADGAQKIVSLVK

Sequences:

>Translated_386_residues
MNIHEYQGKEVLRKYGVAVPEGKVAFTADEAVKAAEALSSSVYVVKAQIHAGGRGKAGGVKIAKSKEEVKAYAEELLGKT
LVTHQTGPDGQQIKRLLIEEGCDIKKEYYVGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIVKEVIDPAVGLQSYQA
RKIAFAINIPKELVGQAVKFMMGLYKAFTEKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRQKDILEYRDLDEEDP
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFG
GIMKCDVIAEGVVEATKQVGLTLPLVVRLEGTNVDLGKKILDDSGLNITSAESMADGAQKIVSLVK
>Mature_386_residues
MNIHEYQGKEVLRKYGVAVPEGKVAFTADEAVKAAEALSSSVYVVKAQIHAGGRGKAGGVKIAKSKEEVKAYAEELLGKT
LVTHQTGPDGQQIKRLLIEEGCDIKKEYYVGLVLDRATSRIVLMASEEGGTEIEEVAEKTPEKIVKEVIDPAVGLQSYQA
RKIAFAINIPKELVGQAVKFMMGLYKAFTEKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRQKDILEYRDLDEEDP
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTEAFKIILSDQNVKGIFVNIFG
GIMKCDVIAEGVVEATKQVGLTLPLVVRLEGTNVDLGKKILDDSGLNITSAESMADGAQKIVSLVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=48.5933503836317, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.2140992167102, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.6824512534819, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=55.1813471502591, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=47.9591836734694, Blast_Score=364, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.8717948717949, Blast_Score=330, Evalue=9e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.6969696969697, Blast_Score=354, Evalue=1e-98,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=45.8015267175573, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=45.8015267175573, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=45.9390862944162, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=45.9390862944162, Blast_Score=336, Evalue=1e-92,
Organism=Drosophila melanogaster, GI21356231, Length=391, Percent_Identity=45.5242966751918, Blast_Score=335, Evalue=2e-92,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_BACLD (Q65JP0)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_079002.1
- RefSeq:   YP_091417.1
- HSSP:   P0A836
- ProteinModelPortal:   Q65JP0
- SMR:   Q65JP0
- STRING:   Q65JP0
- EnsemblBacteria:   EBBACT00000057052
- EnsemblBacteria:   EBBACT00000060918
- GeneID:   3030999
- GeneID:   3100045
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01829
- KEGG:   bli:BL01285
- NMPDR:   fig|279010.5.peg.2533
- eggNOG:   COG0045
- GeneTree:   EBGT00050000001392
- HOGENOM:   HBG315432
- OMA:   MADGAEK
- ProtClustDB:   PRK00696
- BioCyc:   BLIC279010-1:BLI01829-MONOMER
- BioCyc:   BLIC279010:BL01285-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41570; Mature: 41570

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEVLRKYGVAVPEGKVAFTADEAVKAAEALSSSVYVVKAQIHAGGRGKAGGV
CCCCHHCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCE
KIAKSKEEVKAYAEELLGKTLVTHQTGPDGQQIKRLLIEEGCDIKKEYYVGLVLDRATSR
EEECCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCHHHEEEEEEECCCCE
IVLMASEEGGTEIEEVAEKTPEKIVKEVIDPAVGLQSYQARKIAFAINIPKELVGQAVKF
EEEEECCCCCCHHHHHHHHCHHHHHHHHHCHHCCCCCCCCEEEEEEEECCHHHHHHHHHH
MMGLYKAFTEKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRQKDILEYRDLDEEDP
HHHHHHHHHCCCCCEEECCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVEATKQVGLTLPLVVRLEGTNVDLGKKI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
LDDSGLNITSAESMADGAQKIVSLVK
HCCCCCCEECHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNIHEYQGKEVLRKYGVAVPEGKVAFTADEAVKAAEALSSSVYVVKAQIHAGGRGKAGGV
CCCCHHCCHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCE
KIAKSKEEVKAYAEELLGKTLVTHQTGPDGQQIKRLLIEEGCDIKKEYYVGLVLDRATSR
EEECCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCHHHEEEEEEECCCCE
IVLMASEEGGTEIEEVAEKTPEKIVKEVIDPAVGLQSYQARKIAFAINIPKELVGQAVKF
EEEEECCCCCCHHHHHHHHCHHHHHHHHHCHHCCCCCCCCEEEEEEEECCHHHHHHHHHH
MMGLYKAFTEKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRQKDILEYRDLDEEDP
HHHHHHHHHCCCCCEEECCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
KEIEASKYDLSYISLDGNIGCMVNGAGLAMSTMDIIKHYGGEPANFLDVGGGATAEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDQNVKGIFVNIFGGIMKCDVIAEGVVEATKQVGLTLPLVVRLEGTNVDLGKKI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHH
LDDSGLNITSAESMADGAQKIVSLVK
HCCCCCCEECHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA