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The map label for this gene is prpC [H]

Identifier: 52785556

GI number: 52785556

Start: 1756038

End: 1756802

Strand: Direct

Name: prpC [H]

Synonym: BLi01797

Alternate gene names: 52785556

Gene position: 1756038-1756802 (Clockwise)

Preceding gene: 52785555

Following gene: 52785557

Centisome position: 41.59

GC content: 51.63

Gene sequence:

>765_bases
TTGAAAACAGCCTTAAAAACGGACAGGGGAAAAATACGCCAGCACAATGAAGACGATGCCGGCATTTTCACAGAAAAAAA
CGGACTGGTATTAGCTGTTGTCTGCGATGGAATGGGAGGTCATCTGGCCGGCGATGTCGCCAGCAGGATGGCCGTCTCAG
CCCTTCGTGATATTTGGGAGGAAACCGAAGAAGTCCCGGCTTCGCCGGCTGAAAGCGAAGCGTGGCTGAAAGAGCAGATT
TCAGCCGTCAACCAAAAACTTTTCGACCATTCGAGGGCCCACGAAGAGTGCCAGGGAATGGGGACAACGGTCGTCTGCGC
TTTATACACGGGAAAAACGCTGACGGTCGCCCATATCGGAGACAGCCGCTGCTATCTCCTGCAAGGCGGAAGTTTCATAC
AGCTGACGGAAGATCACTCGCTTGTCAATGAACTCGTGCGGACTGGGGGGATTTCGAAGGAGGATGCTGAACACCATCCG
CGGAAAAACGTGCTCACAAAAGCGCTCGGCACAGATCCCGAAGTGAAGGTAGAAGCCCACACATTTGAAATCGAACCGGG
TGATCAAGTGCTATTATGTTCTGACGGGCTGACGAATAAAGTGGATGATGAGACACTGAAGGATATGCTCACGACTCTTT
CTTCTGCGGAGGAGAAAGCGGATCAGCTCGTTCAGCTGGCCAATGACAACGGCGGCGAAGACAATATCACCGTCGCGCTA
TTGGAACTTCCTTCTCAAATTGAAGAAGGTGAAGACAAGTGTTAA

Upstream 100 bases:

>100_bases
GTAAATGTCACGATCAGAAGAGAGCAAGGCCATGATATTGACGCTGCCTGCGGACAGCTTCGTGCAAAGGAGCGCCAGGA
AGAGACGAGGTGAATCAAGG

Downstream 100 bases:

>100_bases
TCGGCAGACGGATCAGCGGACGTTACGAAATCCTGCGCGCCATCGGCGGCGGGGGGATGGCGAACGTTTATTTAGCGCTG
GACATCATCCTCGACCGTGA

Product: PrpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKTALKTDRGKIRQHNEDDAGIFTEKNGLVLAVVCDGMGGHLAGDVASRMAVSALRDIWEETEEVPASPAESEAWLKEQI
SAVNQKLFDHSRAHEECQGMGTTVVCALYTGKTLTVAHIGDSRCYLLQGGSFIQLTEDHSLVNELVRTGGISKEDAEHHP
RKNVLTKALGTDPEVKVEAHTFEIEPGDQVLLCSDGLTNKVDDETLKDMLTTLSSAEEKADQLVQLANDNGGEDNITVAL
LELPSQIEEGEDKC

Sequences:

>Translated_254_residues
MKTALKTDRGKIRQHNEDDAGIFTEKNGLVLAVVCDGMGGHLAGDVASRMAVSALRDIWEETEEVPASPAESEAWLKEQI
SAVNQKLFDHSRAHEECQGMGTTVVCALYTGKTLTVAHIGDSRCYLLQGGSFIQLTEDHSLVNELVRTGGISKEDAEHHP
RKNVLTKALGTDPEVKVEAHTFEIEPGDQVLLCSDGLTNKVDDETLKDMLTTLSSAEEKADQLVQLANDNGGEDNITVAL
LELPSQIEEGEDKC
>Mature_254_residues
MKTALKTDRGKIRQHNEDDAGIFTEKNGLVLAVVCDGMGGHLAGDVASRMAVSALRDIWEETEEVPASPAESEAWLKEQI
SAVNQKLFDHSRAHEECQGMGTTVVCALYTGKTLTVAHIGDSRCYLLQGGSFIQLTEDHSLVNELVRTGGISKEDAEHHP
RKNVLTKALGTDPEVKVEAHTFEIEPGDQVLLCSDGLTNKVDDETLKDMLTTLSSAEEKADQLVQLANDNGGEDNITVAL
LELPSQIEEGEDKC

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27567; Mature: 27567

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTALKTDRGKIRQHNEDDAGIFTEKNGLVLAVVCDGMGGHLAGDVASRMAVSALRDIWE
CCCCCCCCCCHHCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ETEEVPASPAESEAWLKEQISAVNQKLFDHSRAHEECQGMGTTVVCALYTGKTLTVAHIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEC
DSRCYLLQGGSFIQLTEDHSLVNELVRTGGISKEDAEHHPRKNVLTKALGTDPEVKVEAH
CCEEEEEECCCEEEEECHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCEEEEEE
TFEIEPGDQVLLCSDGLTNKVDDETLKDMLTTLSSAEEKADQLVQLANDNGGEDNITVAL
EEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LELPSQIEEGEDKC
EECCHHHCCCCCCC
>Mature Secondary Structure
MKTALKTDRGKIRQHNEDDAGIFTEKNGLVLAVVCDGMGGHLAGDVASRMAVSALRDIWE
CCCCCCCCCCHHCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ETEEVPASPAESEAWLKEQISAVNQKLFDHSRAHEECQGMGTTVVCALYTGKTLTVAHIG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEC
DSRCYLLQGGSFIQLTEDHSLVNELVRTGGISKEDAEHHPRKNVLTKALGTDPEVKVEAH
CCEEEEEECCCEEEEECHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCCEEEEEE
TFEIEPGDQVLLCSDGLTNKVDDETLKDMLTTLSSAEEKADQLVQLANDNGGEDNITVAL
EEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LELPSQIEEGEDKC
EECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]