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The map label for this gene is ctaB

Identifier: 52785465

GI number: 52785465

Start: 1663430

End: 1664356

Strand: Direct

Name: ctaB

Synonym: BLi01705

Alternate gene names: 52785465

Gene position: 1663430-1664356 (Clockwise)

Preceding gene: 52785463

Following gene: 52785466

Centisome position: 39.39

GC content: 46.39

Gene sequence:

>927_bases
ATGGCTGAAACAAGAATTACAGCTGATACAGCAATGAATGGACAAATAGAAGAGACGACAGCATGGAAAGATTTCCTCGC
CCTTATCAAAGTCGGGATTGTTTACTCGAACCTGATAACAACTTTTACGGGCATGTGGCTCGCTTTTTACTTTTCAAATC
TGAGCTTTCTAGGAAACCTTGATATCGTGCTGTTCACTTTAGCGGGGTCCTCGCTTATTATTGCAGGCTCATGCGTCATC
AACAACTTTTATGACCGTGATATTGACCAGCTCATGCAGCGGACGAGAACAAGGCCGACGGTGACTGGAAAAATCCAGCC
TTCACAGGCATTGTGGTTCGGCATTCTGCTGACTGCGCTCGGTTTTATCATGCTGCTGATGACCAATCTGACAGCTGCCG
GAGTAGGATTTGTCGGCGTCTTTACGTACGTGTTTCTATACACGATGTGGTCAAAGCGCCGCTATACCGTTAATACGATC
ATCGGAAGTGTGTCAGGGGCTGTTCCACCTTTGATCGGATGGACCGCTGTCCAAGGTTCCATCGGAGTCGAGGCGTGGGT
GCTGTTTTTAATTATGTTTATTTGGCAGATTCCCCACTTTCTGGCGCTTGCGATTAAGAAAACGGAGGAATACAGAGCCG
CAAATATACCGATGCTGCCTGTTGTACACGGTTTTGAAGTGACGAAAAGGCAGATCATCATTTGGATTGCCTGCTTAATG
CCGCTGCCGTTTTTCCTGGGCGGACTCGGACTGCCGATCGTCATTTTGGGGACGGTGCTTAATATCGGCTGGCTCGTTTG
CGGTCTGGTCGGTTACAGAAGCAAAAATATCATGAAGTGGGCAACGCTCATGTTTGTATATTCATTAAATTACTTGACCA
TTTTCTTCGTTGCCATGGTCGTATTTACACTTTTTAAAATTGGATAG

Upstream 100 bases:

>100_bases
TTTTTCCATCCGGTAATCTTGTATGATAGAGTTGTAGGTTTTTTATGAATATACCGCTTCTCTTGACGTGATGAAGGTTT
GAGTAAGGGGGGTTAGTATT

Downstream 100 bases:

>100_bases
AACTCTATAATTCATCACATTGAAGGCTGTCAATTAACACTTCAAGCAGACAACAATCATGTAAAAGCCGCCTTATCGAT
TTTTTCGATTATGTTTAACA

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAETRITADTAMNGQIEETTAWKDFLALIKVGIVYSNLITTFTGMWLAFYFSNLSFLGNLDIVLFTLAGSSLIIAGSCVI
NNFYDRDIDQLMQRTRTRPTVTGKIQPSQALWFGILLTALGFIMLLMTNLTAAGVGFVGVFTYVFLYTMWSKRRYTVNTI
IGSVSGAVPPLIGWTAVQGSIGVEAWVLFLIMFIWQIPHFLALAIKKTEEYRAANIPMLPVVHGFEVTKRQIIIWIACLM
PLPFFLGGLGLPIVILGTVLNIGWLVCGLVGYRSKNIMKWATLMFVYSLNYLTIFFVAMVVFTLFKIG

Sequences:

>Translated_308_residues
MAETRITADTAMNGQIEETTAWKDFLALIKVGIVYSNLITTFTGMWLAFYFSNLSFLGNLDIVLFTLAGSSLIIAGSCVI
NNFYDRDIDQLMQRTRTRPTVTGKIQPSQALWFGILLTALGFIMLLMTNLTAAGVGFVGVFTYVFLYTMWSKRRYTVNTI
IGSVSGAVPPLIGWTAVQGSIGVEAWVLFLIMFIWQIPHFLALAIKKTEEYRAANIPMLPVVHGFEVTKRQIIIWIACLM
PLPFFLGGLGLPIVILGTVLNIGWLVCGLVGYRSKNIMKWATLMFVYSLNYLTIFFVAMVVFTLFKIG
>Mature_307_residues
AETRITADTAMNGQIEETTAWKDFLALIKVGIVYSNLITTFTGMWLAFYFSNLSFLGNLDIVLFTLAGSSLIIAGSCVIN
NFYDRDIDQLMQRTRTRPTVTGKIQPSQALWFGILLTALGFIMLLMTNLTAAGVGFVGVFTYVFLYTMWSKRRYTVNTII
GSVSGAVPPLIGWTAVQGSIGVEAWVLFLIMFIWQIPHFLALAIKKTEEYRAANIPMLPVVHGFEVTKRQIIIWIACLMP
LPFFLGGLGLPIVILGTVLNIGWLVCGLVGYRSKNIMKWATLMFVYSLNYLTIFFVAMVVFTLFKIG

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=161, Percent_Identity=36.6459627329193, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1786631, Length=286, Percent_Identity=38.4615384615385, Blast_Score=176, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71998235, Length=156, Percent_Identity=32.6923076923077, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325085, Length=160, Percent_Identity=33.125, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19921064, Length=157, Percent_Identity=35.031847133758, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_BACLD (Q65K13)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078882.1
- RefSeq:   YP_091294.1
- STRING:   Q65K13
- EnsemblBacteria:   EBBACT00000057104
- EnsemblBacteria:   EBBACT00000062412
- GeneID:   3030844
- GeneID:   3097465
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01705
- KEGG:   bli:BL02979
- NMPDR:   fig|279010.5.peg.1553
- eggNOG:   COG0109
- GeneTree:   EBGT00050000001177
- HOGENOM:   HBG656003
- OMA:   VGYCAVT
- ProtClustDB:   PRK04375
- BioCyc:   BLIC279010-1:BLI01705-MONOMER
- BioCyc:   BLIC279010:BL02979-MONOMER
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 34398; Mature: 34266

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xea40210)-; HASH(0xe097fe0)-; HASH(0xf7773bc)-; HASH(0xf7770c8)-; HASH(0xe54fe84)-; HASH(0xe09804c)-; HASH(0xedd735c)-; HASH(0xf4e0d18)-; HASH(0xecd4c88)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETRITADTAMNGQIEETTAWKDFLALIKVGIVYSNLITTFTGMWLAFYFSNLSFLGNL
CCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DIVLFTLAGSSLIIAGSCVINNFYDRDIDQLMQRTRTRPTVTGKIQPSQALWFGILLTAL
CEEEEEECCCCEEEECHHHHCCHHHCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
GFIMLLMTNLTAAGVGFVGVFTYVFLYTMWSKRRYTVNTIIGSVSGAVPPLIGWTAVQGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCHHHHHHCCCC
IGVEAWVLFLIMFIWQIPHFLALAIKKTEEYRAANIPMLPVVHGFEVTKRQIIIWIACLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
PLPFFLGGLGLPIVILGTVLNIGWLVCGLVGYRSKNIMKWATLMFVYSLNYLTIFFVAMV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VFTLFKIG
HHHHHHCH
>Mature Secondary Structure 
AETRITADTAMNGQIEETTAWKDFLALIKVGIVYSNLITTFTGMWLAFYFSNLSFLGNL
CCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DIVLFTLAGSSLIIAGSCVINNFYDRDIDQLMQRTRTRPTVTGKIQPSQALWFGILLTAL
CEEEEEECCCCEEEECHHHHCCHHHCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
GFIMLLMTNLTAAGVGFVGVFTYVFLYTMWSKRRYTVNTIIGSVSGAVPPLIGWTAVQGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCHHHHHHCCCC
IGVEAWVLFLIMFIWQIPHFLALAIKKTEEYRAANIPMLPVVHGFEVTKRQIIIWIACLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
PLPFFLGGLGLPIVILGTVLNIGWLVCGLVGYRSKNIMKWATLMFVYSLNYLTIFFVAMV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VFTLFKIG
HHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA