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The map label for this gene is pycA [H]

Identifier: 52785463

GI number: 52785463

Start: 1658595

End: 1662038

Strand: Direct

Name: pycA [H]

Synonym: BLi01703

Alternate gene names: 52785463

Gene position: 1658595-1662038 (Clockwise)

Preceding gene: 52785462

Following gene: 52785465

Centisome position: 39.28

GC content: 49.04

Gene sequence:

>3444_bases
ATGTCACAACAGTCTATTCAAAAAGTTCTTGTTGCAAACAGAGGGGAAATCGCTATCCGCGTATTTCGGGCCTGCACAGA
ACTGAATATCCGTACGGTAGCGATCTATTCTAAAGAAGACAGCGGATCTTACCACAGATACAAAGCCGATGAAGCATACC
TGGTCGGCGAAGGGAAAAAGCCGATTGACGCTTATCTTGATATTGAAGGCATCATCGAGATTGCAAAACGCAACCATGTG
GATGCCATCCATCCAGGCTACGGCTTCCTGTCGGAAAACATTCAGTTTGCTAAGCGGTGTGAAGAGGAAGGCATCATCTT
TATCGGACCGACCTCCGAGCACCTCGATATGTTTGGAGACAAAGTAAAAGCCCGCGAACAAGCTGAAAAAGCTGGAATTC
CGGTCATACCGGGGAGCGACGGACCAGTGGCGGATATAGCGGAAGTGAAACAATTTGCGGAAAAGTTCGGATATCCGTTT
ATCATTAAAGCGTCGCTTGGCGGCGGCGGGCGCGGCATGCGGATCGTCAGGGACGAATCGGAGCTGGTGGAGTCCTATAA
TAGGGCGAAATCAGAGGCGAAAGCGGCCTTTGGCAATGATGAAGTTTATGTCGAAAAGCTGATTGAAAAGCCGAAGCACA
TTGAAGTTCAAGTCATCGGAGATAAAGAAGGGAACGTGGTTCACCTTTACGACCGCGACTGCTCTGTGCAAAGGCGTCAT
CAAAAGGTCATCGAAGTGGCGCCGAGCGTTTCGCTTTCTGAATCCCTCCGGGAAAAGATTTGCGATGCTGCCGTTAAGCT
TGCGAAGAATGTTGAATATGTCAATGCCGGTACAGTCGAATTTTTAGTTGCGAACGATGAGTTTTTCTTTATTGAAGTGA
ACCCGCGTGTTCAGGTGGAGCATACCATTACGGAAATGGTAACGGGCGTCGATATCGTTCAGACGCAAATCCTGATCGCT
GCCGGTCTCAGTCTGGACAGCAGCGAAATCAGCATTCCGAACCAGGATGCGATCACGCTGCACGGATATGCGATCCAGTC
AAGGGTTACGACTGAAGATCCGTCAAACAATTTCATGCCTGACACAGGCAAAATCATGGCATATCGCTCAGGCGGCGGTT
TCGGGGTGAGGCTTGATACCGGAAACAGTTTTCAGGGCGCTGTCATTACGCCTTATTACGATTCGCTGCTTGTTAAGCTT
TCAACTTGGGCGCTGACGTTTGAACAGGCGGCAGCCAAAATGGTCCGCAACCTTCAGGAATTCAGGATCAGGGGAATCAA
AACGAACATTCCTTTCCTTGAAAATGTGGCGAAACACGAAAAGTTTCTTACAGGGCAATACGACACGTCTTTTATCGATA
CAACGCCAGAACTTTTTGTCTTTCCTAAGCAGAGAGACCGCGGAACGAAAATGCTGACATATATCGGGAACGTAACGGTC
AACGGCTTCCCGGGCATCGATAAAAAGAAGAAGCCCGAGTTTGATAAGCCGCAGATCGTCAAAACAGATGTCGATCAGCC
AATCGCAAGCGGAACAAAACAGATTCTTGATGAACGCGGAGCCGAAGGGCTCGTCAAATGGGTGAAAGATCAAGAGGAAG
TGCTCCTCACTGATACGACGTTCCGCGACGCCCATCAGTCATTGCTTGCGACAAGAGTCAGAACGCATGACCTGAAAAAA
ATCGCCAATCCGACGGCTGCGCTCTGGCCAGAGCTTTTCAGTCTTGAAATGTGGGGCGGCGCCACATTTGATGTCGCTTA
CCGTTTCTTGAAAGAAGATCCGTGGAAAAGGCTCGAGGAGCTGCGGAAGGAAATTCCGAATACGATGTTTCAAATGCTTT
TGAGATCTTCGAATGCCGTCGGGTATACAAACTACCCTGACAACCTGATTAAAAAGTTCGTCAGCGAATCGGCTGCGGCC
GGAATCGATGTATTCCGCATTTTTGACAGCTTGAACTGGGTTAAAGGGATGACGCTCGCCATTGATGCAGTGCGCGAGTC
AGGCAAGCTTGCCGAAGCGGCGATCTGCTATACAGGGGACATTCTCGATCCGAACAGAAGCAAGTATAATCTTGAATATT
ATACGTCAATGGCAAAAGAGCTTGAAGCTGCGGGGGCGCATATTCTCGGCATTAAAGATATGGCCGGCCTGCTGAGACCT
CAAGCGGCATACGAACTGGTGTCGGCTTTGAAAGAGACGATCGACATTCCGATCCACTTGCATACACACGACACGAGCGG
CAACGGTATTTTTATGTATGCGAAGGCGATAGAAGCAGGCGTCGACATCGTCGACGTAGCGGTCAGCTCGATGGCGGGTC
TGACATCACAGCCAAGCGCAAGCTCGCTTTACCATGCGCTTGAAGGAGATAAACGCCGTCCGCAGTTCAATGTCGATGCG
GTAGAGTCGTTGTCTCAATATTGGGAGTCTGTCAGAAAATATTACAGCGAGTTTGAGAGCGGCATGATTGCGCCTCATAC
CGAAATTTACAAGCATGAAATGCCTGGCGGCCAATACAGCAACCTTCAGCAGCAGGCTAAGGGAGTCGGCCTCGGCGACC
GCTGGAATGAAGTGAAAGAAATGTACAGCCGGGTCAACCACCTGTTCGGGGACATCGTAAAGGTTACGCCGTCATCTAAA
GTCGTCGGGGATATGGCGCTTTACATGGTGCAAAATAACCTGACGGAAGATGATATTTACGAAAGGGGAGAATCTCTCGA
TTTTCCTGACTCGGTTGTCGAGCTTTTTAAAGGGTATATCGGTCAGCCTCACGGCGGATTCCCTGAGAAATTGCAAAAGC
TGATTTTAAAAGGGCAGGAGCCGATTACAGTACGCCCTGGAGAACTGCTTGAACCGGTTTCATTTGACGCTATAAAAGCG
GAATTCTTGGAAAAGCATGGTATGGAGCTTTCCGACCAGGATGCTGTTGCATATGCGCTTTATCCGAAAGTGTTTACCGA
GTATGTCAAGACAGCGGAACTGTACGGGGATATCTCTGTGCTTGATACACCAACCTTCCTCTACGGCATGACCCTCGGCG
AAGAAATCGAGGTCGAGATTGAAAGAGGGAAAACGCTGATCGTCAAACTTGTCTCTATCGGGGAACCGCGTCCGGATGCG
ACGAGAGTCGTTTATTTTGAACTGAACGGCCAGCCTCGCGAAGTGGTCATTAAAGACGAAAGCATTAAATCGTCCGTTCA
TCAAAAGGTGAAAGCCGACCGTTCAAACCCGAATCATATCGCGGCATCTATGCCGGGAACGGTAATCAAGCTTCTTGTAA
GCAAAGGGGACCAAGTGAAGAAGGGCGATCATTTGATGATCAATGAAGCGATGAAAATGGAAACGACCGTTCAGGCTCCG
TTTTCAGGAACTGTTGAAAACATTCACGTTACAAACGGAGAAGCCATTCAAACCGGCGACCTTCTCATTGAACTGAAAAA
ATAA

Upstream 100 bases:

>100_bases
TAAAAAAAGTATAAATTTTTAAAAAACTAAGCGTGTACAATGACCATCCGATTCATTTAGAATAGATACATACTTATAAC
AGCGGATGAGGGGGAACGAC

Downstream 100 bases:

>100_bases
AAGCACGGCCGCTGACTTTTGTCGGCGGCCTCTTTTTATGAAAAAATCCCCCGCAAAAGGCGGAGGATCAACCGTTTATT
TTTATTTTTGCACCTGCCTG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1147; Mature: 1146

Protein sequence:

>1147_residues
MSQQSIQKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSGSYHRYKADEAYLVGEGKKPIDAYLDIEGIIEIAKRNHV
DAIHPGYGFLSENIQFAKRCEEEGIIFIGPTSEHLDMFGDKVKAREQAEKAGIPVIPGSDGPVADIAEVKQFAEKFGYPF
IIKASLGGGGRGMRIVRDESELVESYNRAKSEAKAAFGNDEVYVEKLIEKPKHIEVQVIGDKEGNVVHLYDRDCSVQRRH
QKVIEVAPSVSLSESLREKICDAAVKLAKNVEYVNAGTVEFLVANDEFFFIEVNPRVQVEHTITEMVTGVDIVQTQILIA
AGLSLDSSEISIPNQDAITLHGYAIQSRVTTEDPSNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKL
STWALTFEQAAAKMVRNLQEFRIRGIKTNIPFLENVAKHEKFLTGQYDTSFIDTTPELFVFPKQRDRGTKMLTYIGNVTV
NGFPGIDKKKKPEFDKPQIVKTDVDQPIASGTKQILDERGAEGLVKWVKDQEEVLLTDTTFRDAHQSLLATRVRTHDLKK
IANPTAALWPELFSLEMWGGATFDVAYRFLKEDPWKRLEELRKEIPNTMFQMLLRSSNAVGYTNYPDNLIKKFVSESAAA
GIDVFRIFDSLNWVKGMTLAIDAVRESGKLAEAAICYTGDILDPNRSKYNLEYYTSMAKELEAAGAHILGIKDMAGLLRP
QAAYELVSALKETIDIPIHLHTHDTSGNGIFMYAKAIEAGVDIVDVAVSSMAGLTSQPSASSLYHALEGDKRRPQFNVDA
VESLSQYWESVRKYYSEFESGMIAPHTEIYKHEMPGGQYSNLQQQAKGVGLGDRWNEVKEMYSRVNHLFGDIVKVTPSSK
VVGDMALYMVQNNLTEDDIYERGESLDFPDSVVELFKGYIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFDAIKA
EFLEKHGMELSDQDAVAYALYPKVFTEYVKTAELYGDISVLDTPTFLYGMTLGEEIEVEIERGKTLIVKLVSIGEPRPDA
TRVVYFELNGQPREVVIKDESIKSSVHQKVKADRSNPNHIAASMPGTVIKLLVSKGDQVKKGDHLMINEAMKMETTVQAP
FSGTVENIHVTNGEAIQTGDLLIELKK

Sequences:

>Translated_1147_residues
MSQQSIQKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSGSYHRYKADEAYLVGEGKKPIDAYLDIEGIIEIAKRNHV
DAIHPGYGFLSENIQFAKRCEEEGIIFIGPTSEHLDMFGDKVKAREQAEKAGIPVIPGSDGPVADIAEVKQFAEKFGYPF
IIKASLGGGGRGMRIVRDESELVESYNRAKSEAKAAFGNDEVYVEKLIEKPKHIEVQVIGDKEGNVVHLYDRDCSVQRRH
QKVIEVAPSVSLSESLREKICDAAVKLAKNVEYVNAGTVEFLVANDEFFFIEVNPRVQVEHTITEMVTGVDIVQTQILIA
AGLSLDSSEISIPNQDAITLHGYAIQSRVTTEDPSNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKL
STWALTFEQAAAKMVRNLQEFRIRGIKTNIPFLENVAKHEKFLTGQYDTSFIDTTPELFVFPKQRDRGTKMLTYIGNVTV
NGFPGIDKKKKPEFDKPQIVKTDVDQPIASGTKQILDERGAEGLVKWVKDQEEVLLTDTTFRDAHQSLLATRVRTHDLKK
IANPTAALWPELFSLEMWGGATFDVAYRFLKEDPWKRLEELRKEIPNTMFQMLLRSSNAVGYTNYPDNLIKKFVSESAAA
GIDVFRIFDSLNWVKGMTLAIDAVRESGKLAEAAICYTGDILDPNRSKYNLEYYTSMAKELEAAGAHILGIKDMAGLLRP
QAAYELVSALKETIDIPIHLHTHDTSGNGIFMYAKAIEAGVDIVDVAVSSMAGLTSQPSASSLYHALEGDKRRPQFNVDA
VESLSQYWESVRKYYSEFESGMIAPHTEIYKHEMPGGQYSNLQQQAKGVGLGDRWNEVKEMYSRVNHLFGDIVKVTPSSK
VVGDMALYMVQNNLTEDDIYERGESLDFPDSVVELFKGYIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFDAIKA
EFLEKHGMELSDQDAVAYALYPKVFTEYVKTAELYGDISVLDTPTFLYGMTLGEEIEVEIERGKTLIVKLVSIGEPRPDA
TRVVYFELNGQPREVVIKDESIKSSVHQKVKADRSNPNHIAASMPGTVIKLLVSKGDQVKKGDHLMINEAMKMETTVQAP
FSGTVENIHVTNGEAIQTGDLLIELKK
>Mature_1146_residues
SQQSIQKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSGSYHRYKADEAYLVGEGKKPIDAYLDIEGIIEIAKRNHVD
AIHPGYGFLSENIQFAKRCEEEGIIFIGPTSEHLDMFGDKVKAREQAEKAGIPVIPGSDGPVADIAEVKQFAEKFGYPFI
IKASLGGGGRGMRIVRDESELVESYNRAKSEAKAAFGNDEVYVEKLIEKPKHIEVQVIGDKEGNVVHLYDRDCSVQRRHQ
KVIEVAPSVSLSESLREKICDAAVKLAKNVEYVNAGTVEFLVANDEFFFIEVNPRVQVEHTITEMVTGVDIVQTQILIAA
GLSLDSSEISIPNQDAITLHGYAIQSRVTTEDPSNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKLS
TWALTFEQAAAKMVRNLQEFRIRGIKTNIPFLENVAKHEKFLTGQYDTSFIDTTPELFVFPKQRDRGTKMLTYIGNVTVN
GFPGIDKKKKPEFDKPQIVKTDVDQPIASGTKQILDERGAEGLVKWVKDQEEVLLTDTTFRDAHQSLLATRVRTHDLKKI
ANPTAALWPELFSLEMWGGATFDVAYRFLKEDPWKRLEELRKEIPNTMFQMLLRSSNAVGYTNYPDNLIKKFVSESAAAG
IDVFRIFDSLNWVKGMTLAIDAVRESGKLAEAAICYTGDILDPNRSKYNLEYYTSMAKELEAAGAHILGIKDMAGLLRPQ
AAYELVSALKETIDIPIHLHTHDTSGNGIFMYAKAIEAGVDIVDVAVSSMAGLTSQPSASSLYHALEGDKRRPQFNVDAV
ESLSQYWESVRKYYSEFESGMIAPHTEIYKHEMPGGQYSNLQQQAKGVGLGDRWNEVKEMYSRVNHLFGDIVKVTPSSKV
VGDMALYMVQNNLTEDDIYERGESLDFPDSVVELFKGYIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFDAIKAE
FLEKHGMELSDQDAVAYALYPKVFTEYVKTAELYGDISVLDTPTFLYGMTLGEEIEVEIERGKTLIVKLVSIGEPRPDAT
RVVYFELNGQPREVVIKDESIKSSVHQKVKADRSNPNHIAASMPGTVIKLLVSKGDQVKKGDHLMINEAMKMETTVQAPF
SGTVENIHVTNGEAIQTGDLLIELKK

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1151, Percent_Identity=50.9122502172024, Blast_Score=1167, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1151, Percent_Identity=50.9122502172024, Blast_Score=1167, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1151, Percent_Identity=50.9122502172024, Blast_Score=1167, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=451, Percent_Identity=45.4545454545455, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI65506442, Length=462, Percent_Identity=42.4242424242424, Blast_Score=359, Evalue=1e-98,
Organism=Homo sapiens, GI295821183, Length=462, Percent_Identity=42.4242424242424, Blast_Score=358, Evalue=1e-98,
Organism=Homo sapiens, GI189095269, Length=460, Percent_Identity=42.6086956521739, Blast_Score=358, Evalue=2e-98,
Organism=Homo sapiens, GI38679960, Length=515, Percent_Identity=32.8155339805825, Blast_Score=256, Evalue=9e-68,
Organism=Homo sapiens, GI38679977, Length=515, Percent_Identity=32.8155339805825, Blast_Score=256, Evalue=1e-67,
Organism=Homo sapiens, GI38679967, Length=515, Percent_Identity=32.8155339805825, Blast_Score=256, Evalue=1e-67,
Organism=Homo sapiens, GI38679971, Length=515, Percent_Identity=32.8155339805825, Blast_Score=256, Evalue=1e-67,
Organism=Homo sapiens, GI38679974, Length=515, Percent_Identity=32.8155339805825, Blast_Score=256, Evalue=1e-67,
Organism=Homo sapiens, GI134142062, Length=509, Percent_Identity=31.8271119842829, Blast_Score=244, Evalue=5e-64,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=46.1024498886414, Blast_Score=384, Evalue=1e-107,
Organism=Escherichia coli, GI1786216, Length=270, Percent_Identity=24.8148148148148, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562816, Length=1148, Percent_Identity=50.2613240418118, Blast_Score=1155, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=461, Percent_Identity=43.6008676789588, Blast_Score=350, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17567343, Length=467, Percent_Identity=42.8265524625268, Blast_Score=348, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI133931226, Length=497, Percent_Identity=30.3822937625755, Blast_Score=213, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI71997163, Length=440, Percent_Identity=29.0909090909091, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71997168, Length=438, Percent_Identity=29.2237442922374, Blast_Score=201, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1158, Percent_Identity=49.4818652849741, Blast_Score=1110, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1157, Percent_Identity=49.5246326707001, Blast_Score=1100, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=37.7777777777778, Blast_Score=299, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6324343, Length=514, Percent_Identity=31.1284046692607, Blast_Score=227, Evalue=7e-60,
Organism=Saccharomyces cerevisiae, GI6323863, Length=471, Percent_Identity=30.9978768577495, Blast_Score=221, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6322331, Length=313, Percent_Identity=21.7252396166134, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24652212, Length=1146, Percent_Identity=51.5706806282722, Blast_Score=1169, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1146, Percent_Identity=51.5706806282722, Blast_Score=1169, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1146, Percent_Identity=51.5706806282722, Blast_Score=1169, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1146, Percent_Identity=51.5706806282722, Blast_Score=1169, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1146, Percent_Identity=51.5706806282722, Blast_Score=1169, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1162, Percent_Identity=51.2048192771084, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1162, Percent_Identity=51.2048192771084, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1162, Percent_Identity=51.2048192771084, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1162, Percent_Identity=51.2048192771084, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1162, Percent_Identity=51.2048192771084, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=471, Percent_Identity=42.6751592356688, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24651759, Length=430, Percent_Identity=42.093023255814, Blast_Score=332, Evalue=7e-91,
Organism=Drosophila melanogaster, GI161076409, Length=505, Percent_Identity=32.6732673267327, Blast_Score=242, Evalue=1e-63,
Organism=Drosophila melanogaster, GI161076407, Length=505, Percent_Identity=32.6732673267327, Blast_Score=242, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24586460, Length=505, Percent_Identity=32.6732673267327, Blast_Score=242, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24586458, Length=505, Percent_Identity=32.6732673267327, Blast_Score=242, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127767; Mature: 127636

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQSIQKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSGSYHRYKADEAYLVGEGKK
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEECCCEEEEECCCC
PIDAYLDIEGIIEIAKRNHVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPTSEHLDMFGD
CCHHHCCHHHHHHHHHCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCHHHHHHHHH
KVKAREQAEKAGIPVIPGSDGPVADIAEVKQFAEKFGYPFIIKASLGGGGRGMRIVRDES
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECHH
ELVESYNRAKSEAKAAFGNDEVYVEKLIEKPKHIEVQVIGDKEGNVVHLYDRDCSVQRRH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
QKVIEVAPSVSLSESLREKICDAAVKLAKNVEYVNAGTVEFLVANDEFFFIEVNPRVQVE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCEEEEEEECCCEEEH
HTITEMVTGVDIVQTQILIAAGLSLDSSEISIPNQDAITLHGYAIQSRVTTEDPSNNFMP
HHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCC
DTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKLSTWALTFEQAAAKMVRNLQE
CCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIRGIKTNIPFLENVAKHEKFLTGQYDTSFIDTTPELFVFPKQRDRGTKMLTYIGNVTV
HHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCCCCCCCEEEEEECCEEE
NGFPGIDKKKKPEFDKPQIVKTDVDQPIASGTKQILDERGAEGLVKWVKDQEEVLLTDTT
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECC
FRDAHQSLLATRVRTHDLKKIANPTAALWPELFSLEMWGGATFDVAYRFLKEDPWKRLEE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHHHHCCHHHHHHH
LRKEIPNTMFQMLLRSSNAVGYTNYPDNLIKKFVSESAAAGIDVFRIFDSLNWVKGMTLA
HHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
IDAVRESGKLAEAAICYTGDILDPNRSKYNLEYYTSMAKELEAAGAHILGIKDMAGLLRP
HHHHHHCCCHHHEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHCC
QAAYELVSALKETIDIPIHLHTHDTSGNGIFMYAKAIEAGVDIVDVAVSSMAGLTSQPSA
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCCCCH
SSLYHALEGDKRRPQFNVDAVESLSQYWESVRKYYSEFESGMIAPHTEIYKHEMPGGQYS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHH
NLQQQAKGVGLGDRWNEVKEMYSRVNHLFGDIVKVTPSSKVVGDMALYMVQNNLTEDDIY
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHH
ERGESLDFPDSVVELFKGYIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFDAIKA
HCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCHHCCCCCHHHHHH
EFLEKHGMELSDQDAVAYALYPKVFTEYVKTAELYGDISVLDTPTFLYGMTLGEEIEVEI
HHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEECCCHHEEECCCCCEEEEEE
ERGKTLIVKLVSIGEPRPDATRVVYFELNGQPREVVIKDESIKSSVHQKVKADRSNPNHI
ECCCEEEEEEECCCCCCCCCEEEEEEEECCCCCEEEEECHHHHHHHHHHHHCCCCCCCEE
AASMPGTVIKLLVSKGDQVKKGDHLMINEAMKMETTVQAPFSGTVENIHVTNGEAIQTGD
EECCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHEEEECCCCCCCCEEEECCCCEEEECC
LLIELKK
EEEEECC
>Mature Secondary Structure 
SQQSIQKVLVANRGEIAIRVFRACTELNIRTVAIYSKEDSGSYHRYKADEAYLVGEGKK
CHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCEEEEECCCEEEEECCCC
PIDAYLDIEGIIEIAKRNHVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPTSEHLDMFGD
CCHHHCCHHHHHHHHHCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCHHHHHHHHH
KVKAREQAEKAGIPVIPGSDGPVADIAEVKQFAEKFGYPFIIKASLGGGGRGMRIVRDES
HHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECHH
ELVESYNRAKSEAKAAFGNDEVYVEKLIEKPKHIEVQVIGDKEGNVVHLYDRDCSVQRRH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
QKVIEVAPSVSLSESLREKICDAAVKLAKNVEYVNAGTVEFLVANDEFFFIEVNPRVQVE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCEEEEEEECCCEEEH
HTITEMVTGVDIVQTQILIAAGLSLDSSEISIPNQDAITLHGYAIQSRVTTEDPSNNFMP
HHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCC
DTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKLSTWALTFEQAAAKMVRNLQE
CCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIRGIKTNIPFLENVAKHEKFLTGQYDTSFIDTTPELFVFPKQRDRGTKMLTYIGNVTV
HHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCCCCCCCEEEEEECCEEE
NGFPGIDKKKKPEFDKPQIVKTDVDQPIASGTKQILDERGAEGLVKWVKDQEEVLLTDTT
CCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECC
FRDAHQSLLATRVRTHDLKKIANPTAALWPELFSLEMWGGATFDVAYRFLKEDPWKRLEE
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHHHHCCHHHHHHH
LRKEIPNTMFQMLLRSSNAVGYTNYPDNLIKKFVSESAAAGIDVFRIFDSLNWVKGMTLA
HHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
IDAVRESGKLAEAAICYTGDILDPNRSKYNLEYYTSMAKELEAAGAHILGIKDMAGLLRP
HHHHHHCCCHHHEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHCC
QAAYELVSALKETIDIPIHLHTHDTSGNGIFMYAKAIEAGVDIVDVAVSSMAGLTSQPSA
HHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEHHHCCCHHHHHHHHHHCCCCCCCCH
SSLYHALEGDKRRPQFNVDAVESLSQYWESVRKYYSEFESGMIAPHTEIYKHEMPGGQYS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHH
NLQQQAKGVGLGDRWNEVKEMYSRVNHLFGDIVKVTPSSKVVGDMALYMVQNNLTEDDIY
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHH
ERGESLDFPDSVVELFKGYIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFDAIKA
HCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEECCCHHCCCCCHHHHHH
EFLEKHGMELSDQDAVAYALYPKVFTEYVKTAELYGDISVLDTPTFLYGMTLGEEIEVEI
HHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEECCCHHEEECCCCCEEEEEE
ERGKTLIVKLVSIGEPRPDATRVVYFELNGQPREVVIKDESIKSSVHQKVKADRSNPNHI
ECCCEEEEEEECCCCCCCCCEEEEEEEECCCCCEEEEECHHHHHHHHHHHHCCCCCCCEE
AASMPGTVIKLLVSKGDQVKKGDHLMINEAMKMETTVQAPFSGTVENIHVTNGEAIQTGD
EECCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHEEEECCCCCCCCEEEECCCCEEEECC
LLIELKK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]