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The map label for this gene is pdhB [H]

Identifier: 52785435

GI number: 52785435

Start: 1633778

End: 1634755

Strand: Direct

Name: pdhB [H]

Synonym: BLi01675

Alternate gene names: 52785435

Gene position: 1633778-1634755 (Clockwise)

Preceding gene: 52785434

Following gene: 52785436

Centisome position: 38.69

GC content: 48.88

Gene sequence:

>978_bases
ATGGCGCAAATGACAATGATTCAAGCAATCACTGATGCGTTACGCACAGAACTGAAAAATGACGAAAATGTCTTAGTTTT
CGGAGAAGACGTCGGTGTTAACGGCGGCGTGTTCCGTGCGACTGAAGGATTGCAAAAAGAGTTTGGTGAGGATCGCGTAT
TTGACACTCCTCTTGCTGAATCTGGTATCGGCGGCCTTGCACTCGGCTTAGGCTTACAAGGCTTCCGTCCTGTAATGGAA
ATTCAATTTTTCGGCTTTGTGTATGAAGTGATGGACTCTGTTTCCGGACAAATGGCACGGATGCGCTACCGTTCCGGCGG
TCGCTGGAATTCTCCGGTGACAATCCGTTCTCCGTTCGGCGGCGGTGTTCATACGCCTGAACTTCACGCGGACAGCTTGG
AAGGACTCGTTGCACAGCAGCCTGGACTTAAAGTCGTTATTCCTTCAACTCCGTACGATGCTAAAGGACTTTTAATCTCT
GCGATCCGCGATAACGATCCGGTTGTCTTCCTTGAGCACATGAAACTTTACCGTTCATTCCGCCAGGAAGTTCCTGAAGA
GGAATACACAATTGAAATCGGCAAAGCCGATGTGAAACGCGAAGGAAAAGACCTTTCCATCATCACATACGGAGCGATGG
TTCACGAGTCATTAAAAGCGGCGGAAGAGCTTGAAAAAGAAGGCGTATCTGCTGAGGTTGTCGACCTTCGCACAGTCAGC
CCGCTTGACATTGACACGATCATCGCGTCTGTAGAAAAAACAGGCCGCGCAATCGTCGTTCAAGAGGCGCAAAAACAGGC
TGGAGTAGCTGCAAACGTTGTTGCCGAAATCAACGACCGCGCGATTTTGAGCCTCGAAGCTCCAGTGCTTCGCGTCACTG
CTCCTGATACTGTATTCGCATTCTCTCAAGCTGAAAGCGTATGGCTTCCAAACCATAAAGACGTGCTTGAAACTGCGAAA
AAAGTATTGGAATTTTAA

Upstream 100 bases:

>100_bases
GCAAAAAGTGACCGACCTGATCGACATTATGTATGAAGAGCTTCCTTACAACCTTGTAGAACAAAAGGAAATTTATAAAG
AGAAGGAGTCGAAGTAAGCC

Downstream 100 bases:

>100_bases
TTAGATCTGAACAATTCAAAAGGGAAAAGCTGATATCAGCCTTTTTCCCTTCATGCATTTCCACAGTCAGTCGGAGAAAC
TGTAGCCGTGTACTGACAGT

Product: hypothetical protein

Products: NA

Alternate protein names: S complex, 36 kDa subunit [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGIGGLALGLGLQGFRPVME
IQFFGFVYEVMDSVSGQMARMRYRSGGRWNSPVTIRSPFGGGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLIS
AIRDNDPVVFLEHMKLYRSFRQEVPEEEYTIEIGKADVKREGKDLSIITYGAMVHESLKAAEELEKEGVSAEVVDLRTVS
PLDIDTIIASVEKTGRAIVVQEAQKQAGVAANVVAEINDRAILSLEAPVLRVTAPDTVFAFSQAESVWLPNHKDVLETAK
KVLEF

Sequences:

>Translated_325_residues
MAQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGIGGLALGLGLQGFRPVME
IQFFGFVYEVMDSVSGQMARMRYRSGGRWNSPVTIRSPFGGGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLIS
AIRDNDPVVFLEHMKLYRSFRQEVPEEEYTIEIGKADVKREGKDLSIITYGAMVHESLKAAEELEKEGVSAEVVDLRTVS
PLDIDTIIASVEKTGRAIVVQEAQKQAGVAANVVAEINDRAILSLEAPVLRVTAPDTVFAFSQAESVWLPNHKDVLETAK
KVLEF
>Mature_324_residues
AQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAESGIGGLALGLGLQGFRPVMEI
QFFGFVYEVMDSVSGQMARMRYRSGGRWNSPVTIRSPFGGGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLISA
IRDNDPVVFLEHMKLYRSFRQEVPEEEYTIEIGKADVKREGKDLSIITYGAMVHESLKAAEELEKEGVSAEVVDLRTVSP
LDIDTIIASVEKTGRAIVVQEAQKQAGVAANVVAEINDRAILSLEAPVLRVTAPDTVFAFSQAESVWLPNHKDVLETAKK
VLEF

Specific function: The B.subtilis PDH complex possesses also branched-chain 2-oxoacid dehydrogenase (BCDH) activity [H]

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=325, Percent_Identity=40.9230769230769, Blast_Score=262, Evalue=3e-70,
Organism=Homo sapiens, GI34101272, Length=325, Percent_Identity=40.9230769230769, Blast_Score=262, Evalue=3e-70,
Organism=Homo sapiens, GI156564403, Length=327, Percent_Identity=36.697247706422, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI291084858, Length=326, Percent_Identity=35.2760736196319, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI225637461, Length=254, Percent_Identity=29.1338582677165, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI225637459, Length=254, Percent_Identity=29.1338582677165, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI225637463, Length=254, Percent_Identity=29.1338582677165, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI133778974, Length=97, Percent_Identity=38.1443298969072, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17506935, Length=326, Percent_Identity=40.1840490797546, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17538422, Length=328, Percent_Identity=37.5, Blast_Score=224, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6319698, Length=328, Percent_Identity=39.6341463414634, Blast_Score=218, Evalue=7e-58,
Organism=Drosophila melanogaster, GI160714832, Length=325, Percent_Identity=39.0769230769231, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI160714828, Length=325, Percent_Identity=39.0769230769231, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI21358145, Length=326, Percent_Identity=38.6503067484663, Blast_Score=231, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24650940, Length=326, Percent_Identity=38.6503067484663, Blast_Score=231, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24650943, Length=90, Percent_Identity=38.8888888888889, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24650945, Length=90, Percent_Identity=38.8888888888889, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 35505; Mature: 35374

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAE
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEHHHHHHHHHCCCCCCCCCCCHH
SGIGGLALGLGLQGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWNSPVTIRSPFG
CCCCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLISAIRDNDPVVFLEHMKLYRSF
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHH
RQEVPEEEYTIEIGKADVKREGKDLSIITYGAMVHESLKAAEELEKEGVSAEVVDLRTVS
HHHCCCCCEEEEECCHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PLDIDTIIASVEKTGRAIVVQEAQKQAGVAANVVAEINDRAILSLEAPVLRVTAPDTVFA
CCCHHHHHHHHHHCCCEEEEEHHHHHCCCHHHHHEECCCCEEEEECCCEEEEECCCCEEE
FSQAESVWLPNHKDVLETAKKVLEF
ECCCCCEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AQMTMIQAITDALRTELKNDENVLVFGEDVGVNGGVFRATEGLQKEFGEDRVFDTPLAE
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEHHHHHHHHHCCCCCCCCCCCHH
SGIGGLALGLGLQGFRPVMEIQFFGFVYEVMDSVSGQMARMRYRSGGRWNSPVTIRSPFG
CCCCHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GGVHTPELHADSLEGLVAQQPGLKVVIPSTPYDAKGLLISAIRDNDPVVFLEHMKLYRSF
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHH
RQEVPEEEYTIEIGKADVKREGKDLSIITYGAMVHESLKAAEELEKEGVSAEVVDLRTVS
HHHCCCCCEEEEECCHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PLDIDTIIASVEKTGRAIVVQEAQKQAGVAANVVAEINDRAILSLEAPVLRVTAPDTVFA
CCCHHHHHHHHHHCCCEEEEEHHHHHCCCHHHHHEECCCCEEEEECCCEEEEECCCCEEE
FSQAESVWLPNHKDVLETAKKVLEF
ECCCCCEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1697575; 8969500; 9384377 [H]