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The map label for this gene is sipT

Identifier: 52785416

GI number: 52785416

Start: 1616678

End: 1617238

Strand: Direct

Name: sipT

Synonym: BLi01655

Alternate gene names: 52785416

Gene position: 1616678-1617238 (Clockwise)

Preceding gene: 52785415

Following gene: 52785419

Centisome position: 38.29

GC content: 47.59

Gene sequence:

>561_bases
TTGACTGAAGAAAAATCCACCAATAAGAAAAACTCTCTCTTTGAATGGGTAAAAGCCATTATTATTGCAGTCGTTCTGGC
GTTATTGATCAGGGCATTTTTATTCGAACCGTATTTAGTGGAAGGTACGTCGATGGACCCGACGCTGCACGACGGAGAGC
GGCTGTTCGTCTATAAAACGGTTAGATACGTAGGCGAATTTAAGCGGGGAGATATCGTCATTATCGACGGCGACGAAAAG
AATGTCCATTATGTAAAGCGCTTGATCGGCCTGCCGGGAGATACCGTGCAAATGAAAGATGACACGCTGTACATAAACGG
GAAGAAGGTGTCGGAGCCGTATCTTTCGGAAAACAGAAAAGAGGCGGAAGCAGTCGGCGTCAAGCTGACGGGCGACTTTG
GCCCTGTGAAGGTTCCCGAAGGCAAGTATTTCGTGATGGGAGACAATCGCCAGAGGTCAATGGACAGCCGGAACGGCCTC
GGACTGATTGATAAAAAACGAGTGGCCGGAACTTCGCAATTTGTGTTTTTCCCGTTTAACGAAATCCGAAAAACAGACTG
A

Upstream 100 bases:

>100_bases
GCGCGGGGATTATGTATTCAGCGGGAACTTGTGATAAAGTATAGGAAAGCTTTTATTTTGGCATGTATGCTGTGACAGAC
TGTTTTTAGGAGGAAGCGTT

Downstream 100 bases:

>100_bases
AAAATGCCTGATGTCCATTTGGACAATCAGGCATTTTTGCTTGATTTATGCGGATAATGATGCCAGCACTGCGATAAACA
GTACGGTAACGAACACAGAG

Product: SipT

Products: NA

Alternate protein names: SPase I; Leader peptidase I

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTEEKSTNKKNSLFEWVKAIIIAVVLALLIRAFLFEPYLVEGTSMDPTLHDGERLFVYKTVRYVGEFKRGDIVIIDGDEK
NVHYVKRLIGLPGDTVQMKDDTLYINGKKVSEPYLSENRKEAEAVGVKLTGDFGPVKVPEGKYFVMGDNRQRSMDSRNGL
GLIDKKRVAGTSQFVFFPFNEIRKTD

Sequences:

>Translated_186_residues
MTEEKSTNKKNSLFEWVKAIIIAVVLALLIRAFLFEPYLVEGTSMDPTLHDGERLFVYKTVRYVGEFKRGDIVIIDGDEK
NVHYVKRLIGLPGDTVQMKDDTLYINGKKVSEPYLSENRKEAEAVGVKLTGDFGPVKVPEGKYFVMGDNRQRSMDSRNGL
GLIDKKRVAGTSQFVFFPFNEIRKTD
>Mature_185_residues
TEEKSTNKKNSLFEWVKAIIIAVVLALLIRAFLFEPYLVEGTSMDPTLHDGERLFVYKTVRYVGEFKRGDIVIIDGDEKN
VHYVKRLIGLPGDTVQMKDDTLYINGKKVSEPYLSENRKEAEAVGVKLTGDFGPVKVPEGKYFVMGDNRQRSMDSRNGLG
LIDKKRVAGTSQFVFFPFNEIRKTD

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LEP_BACLI (P42668)

Other databases:

- EMBL:   X75604
- ProteinModelPortal:   P42668
- SMR:   P42668
- MEROPS:   S26.004
- PhylomeDB:   P42668
- BRENDA:   3.4.21.89
- GO:   GO:0006508
- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- Gene3D:   G3DSA:2.10.109.10
- PRINTS:   PR00727
- TIGRFAMs:   TIGR02227

Pfam domain/function: PF00717 Peptidase_S24; SSF51306 Pept_S24_S26_C

EC number: =3.4.21.89

Molecular weight: Translated: 21146; Mature: 21014

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00501 SPASE_I_1; PS00760 SPASE_I_2; PS00761 SPASE_I_3

Important sites: ACT_SITE 44-44 ACT_SITE 86-86

Signals:

None

Transmembrane regions:

HASH(0xea8f8bc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEKSTNKKNSLFEWVKAIIIAVVLALLIRAFLFEPYLVEGTSMDPTLHDGERLFVYKT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEHH
VRYVGEFKRGDIVIIDGDEKNVHYVKRLIGLPGDTVQMKDDTLYINGKKVSEPYLSENRK
HHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCHHHCCCC
EAEAVGVKLTGDFGPVKVPEGKYFVMGDNRQRSMDSRNGLGLIDKKRVAGTSQFVFFPFN
CHHHEEEEEECCCCCEECCCCCEEEEECCHHHCCCCCCCCCCCCCHHCCCCCEEEEEEHH
EIRKTD
HHCCCH
>Mature Secondary Structure 
TEEKSTNKKNSLFEWVKAIIIAVVLALLIRAFLFEPYLVEGTSMDPTLHDGERLFVYKT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEHH
VRYVGEFKRGDIVIIDGDEKNVHYVKRLIGLPGDTVQMKDDTLYINGKKVSEPYLSENRK
HHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCHHHCCCC
EAEAVGVKLTGDFGPVKVPEGKYFVMGDNRQRSMDSRNGLGLIDKKRVAGTSQFVFFPFN
CHHHEEEEEECCCCCEECCCCCEEEEECCHHHCCCCCCCCCCCCCHHCCCCCEEEEEEHH
EIRKTD
HHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA