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The map label for this gene is fruA [H]

Identifier: 52785415

GI number: 52785415

Start: 1614616

End: 1616511

Strand: Direct

Name: fruA [H]

Synonym: BLi01654

Alternate gene names: 52785415

Gene position: 1614616-1616511 (Clockwise)

Preceding gene: 52785414

Following gene: 52785416

Centisome position: 38.24

GC content: 49.0

Gene sequence:

>1896_bases
ATGAAAATAACTGAGCTACTAACAAAGCATACGATCAAGTTAAACCTTGAGAGCAGCCAGAAAGAAAACGTTATCGAAGA
ACTCGTCAGCGTTTTGGATCAGGCTGGCAAGTTGAATGATAAAGAAGGCTACAAAGAAGCTGTGATCAACCGCGAGAAAC
AAAGCTCTACCGGTATCGGCGAAGGCATCGCCATCCCGCATGCGAAAACGGCAAGCGTCAAAGAGCCTGCGATCGCGTTC
GGCCGTTCAAAAGGCGGCGTCGATTATGAATCCCTTGACGGCCAGCCAAGCCATCTCGTTTTCATGATCGCCGCTACAGA
CGGTGCAAATAACACTCACCTCGAAGCATTGTCAAGACTGTCGACTTTGCTTATGAGGGAGGAGATTCGCAAACAGCTGC
TTGAAGCTTCATCTGAAGACGAAATCATCGACATCATCAATCAGCATGATAAAGATGATGATGAAGAAGAAGAGCAGGCC
GAAGAGGCTCCTGCACCATCAGCAAAAGGAAAAATCCTTGCGGTTACAGCATGCCCGACAGGGATCGCCCACACGTTCAT
GGCTGCGGATGCTTTGAAAGAAAAAGCGAAAGAGCTTGGGGTTGATATCAAAGTTGAAACGAACGGTTCAAGCGGTATTA
AAAATGGTCTGACGGCCCAGGAAATCGAAGATGCCGTTGCGATCATTGTCGCCGCCGACAAGCAGGTTGAAATGGAACGC
TTTCAAGGCAAGCATGTCATTGAAGTACCTGTAACAGCAGGTATCAGACGTCCGCAAGAGCTGATTGAGCAGGCGCTGAA
ACAAGACGCGCCTATCTATCAGGGTAAAGGCGGCGGTGCAACCGCTTCTGAAGACGGAGCTGCCAAAGGAAAAGGCGGCG
GTTTCTACAAACACTTGATGAGCGGTGTCAGCAACATGCTGCCGTTCGTCGTCGGGGGCGGGATCTTAGTTGCGATTTCG
TTCTTCTGGGGAATTAACGCGACCAAGCCGGGAGATCCGACTTATAATGAGTTCGCTGCTGTATTAAATAATATTGGCGG
AACGAATGCACTTGGATTAATTGTCGCTGTATTGGCCGGATTTATCGCGATGAGCATTGCAGATCGTCCGGGATTTGCGC
CTGGTATGGTCGGCGGTTTCATGGCGACACAAGCTGGCGCAGGTTTCTTAGGCGGCCTGATTGCCGGTTTCTTAGCTGGT
TATATTGTTGTCCTGTTGAAAAAAGTGTTCGCTGGTCTGCCGCAAGTGCTTGACGGTTTAAAACCTGTGCTGCTCTACCC
GCTGTTTGGAATATTCTTGACCGGAATCATTATGCAATATGTTGTCAATACGCCTGTCAAGTACATTATGGACGGCATGA
CACATTGGCTTGAAGGTCTTGGAACAGGAAACCTTGTCGTAATGGGTATTGTTTTAGGCGGTATGATGGCGATTGATATG
GGCGGTCCGATCAACAAAGCGGCCTTTACATTCGGTATCGCAATGATTGAAGCTGGAAACTTTGGGCCTCACGCAGCCAT
CATGGCAGGCGGTATGGTGCCTCCGCTTGGAATTGCCCTTGCAACGACTTTCTTTAAAAATAAATTCTCAAAACGGGATC
GCGAAGCCGGAATTACCAACTACGTGATGGGCTTGTCATTTATTACTGAAGGTGCGATTCCTTTTGCGGCAGCAGATCCG
GCACGCGTCATTCCTGCTTGTATCATCGGGTCAGCAGTTGCCGGCGGTCTGTCTCAATTTTTCCATGTCACACTGCAAGC
GCCGCATGGCGGAATATTCGTTCTCTTCTTTACGACGAATCATGCGCTGCTGTATCTCCTCAGCATCTTGATCGGTGCGG
TTGTGACAGCTTTGATTCTCGGCGTTTTGAAAAAGCCGGTTCCAACTGAAAAATAA

Upstream 100 bases:

>100_bases
GGAAGCGCAACTGCCTTTTCAGAGGAGCTGGGAACGGAAGAGCTCGTTCACAAGCTGCTTCCGGAAGTTCAAGTCAAAGC
GATATAAAGGAGGAAAGGTT

Downstream 100 bases:

>100_bases
GTGCTGAAAGTGCCACAGTAATCCCTCTCGTGGCACTTTCTTTTTTACTGTTTTTGCCGGAAGTGAGCGCGGGGATTATG
TATTCAGCGGGAACTTGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MKITELLTKHTIKLNLESSQKENVIEELVSVLDQAGKLNDKEGYKEAVINREKQSSTGIGEGIAIPHAKTASVKEPAIAF
GRSKGGVDYESLDGQPSHLVFMIAATDGANNTHLEALSRLSTLLMREEIRKQLLEASSEDEIIDIINQHDKDDDEEEEQA
EEAPAPSAKGKILAVTACPTGIAHTFMAADALKEKAKELGVDIKVETNGSSGIKNGLTAQEIEDAVAIIVAADKQVEMER
FQGKHVIEVPVTAGIRRPQELIEQALKQDAPIYQGKGGGATASEDGAAKGKGGGFYKHLMSGVSNMLPFVVGGGILVAIS
FFWGINATKPGDPTYNEFAAVLNNIGGTNALGLIVAVLAGFIAMSIADRPGFAPGMVGGFMATQAGAGFLGGLIAGFLAG
YIVVLLKKVFAGLPQVLDGLKPVLLYPLFGIFLTGIIMQYVVNTPVKYIMDGMTHWLEGLGTGNLVVMGIVLGGMMAIDM
GGPINKAAFTFGIAMIEAGNFGPHAAIMAGGMVPPLGIALATTFFKNKFSKRDREAGITNYVMGLSFITEGAIPFAAADP
ARVIPACIIGSAVAGGLSQFFHVTLQAPHGGIFVLFFTTNHALLYLLSILIGAVVTALILGVLKKPVPTEK

Sequences:

>Translated_631_residues
MKITELLTKHTIKLNLESSQKENVIEELVSVLDQAGKLNDKEGYKEAVINREKQSSTGIGEGIAIPHAKTASVKEPAIAF
GRSKGGVDYESLDGQPSHLVFMIAATDGANNTHLEALSRLSTLLMREEIRKQLLEASSEDEIIDIINQHDKDDDEEEEQA
EEAPAPSAKGKILAVTACPTGIAHTFMAADALKEKAKELGVDIKVETNGSSGIKNGLTAQEIEDAVAIIVAADKQVEMER
FQGKHVIEVPVTAGIRRPQELIEQALKQDAPIYQGKGGGATASEDGAAKGKGGGFYKHLMSGVSNMLPFVVGGGILVAIS
FFWGINATKPGDPTYNEFAAVLNNIGGTNALGLIVAVLAGFIAMSIADRPGFAPGMVGGFMATQAGAGFLGGLIAGFLAG
YIVVLLKKVFAGLPQVLDGLKPVLLYPLFGIFLTGIIMQYVVNTPVKYIMDGMTHWLEGLGTGNLVVMGIVLGGMMAIDM
GGPINKAAFTFGIAMIEAGNFGPHAAIMAGGMVPPLGIALATTFFKNKFSKRDREAGITNYVMGLSFITEGAIPFAAADP
ARVIPACIIGSAVAGGLSQFFHVTLQAPHGGIFVLFFTTNHALLYLLSILIGAVVTALILGVLKKPVPTEK
>Mature_631_residues
MKITELLTKHTIKLNLESSQKENVIEELVSVLDQAGKLNDKEGYKEAVINREKQSSTGIGEGIAIPHAKTASVKEPAIAF
GRSKGGVDYESLDGQPSHLVFMIAATDGANNTHLEALSRLSTLLMREEIRKQLLEASSEDEIIDIINQHDKDDDEEEEQA
EEAPAPSAKGKILAVTACPTGIAHTFMAADALKEKAKELGVDIKVETNGSSGIKNGLTAQEIEDAVAIIVAADKQVEMER
FQGKHVIEVPVTAGIRRPQELIEQALKQDAPIYQGKGGGATASEDGAAKGKGGGFYKHLMSGVSNMLPFVVGGGILVAIS
FFWGINATKPGDPTYNEFAAVLNNIGGTNALGLIVAVLAGFIAMSIADRPGFAPGMVGGFMATQAGAGFLGGLIAGFLAG
YIVVLLKKVFAGLPQVLDGLKPVLLYPLFGIFLTGIIMQYVVNTPVKYIMDGMTHWLEGLGTGNLVVMGIVLGGMMAIDM
GGPINKAAFTFGIAMIEAGNFGPHAAIMAGGMVPPLGIALATTFFKNKFSKRDREAGITNYVMGLSFITEGAIPFAAADP
ARVIPACIIGSAVAGGLSQFFHVTLQAPHGGIFVLFFTTNHALLYLLSILIGAVVTALILGVLKKPVPTEK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=463, Percent_Identity=46.8682505399568, Blast_Score=417, Evalue=1e-117,
Organism=Escherichia coli, GI1786951, Length=636, Percent_Identity=33.4905660377358, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI87082348, Length=441, Percent_Identity=33.5600907029478, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1790386, Length=302, Percent_Identity=39.0728476821192, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1788729, Length=405, Percent_Identity=27.9012345679012, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790387, Length=104, Percent_Identity=44.2307692307692, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788730, Length=88, Percent_Identity=47.7272727272727, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI2367327, Length=142, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789597, Length=111, Percent_Identity=35.1351351351351, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994992, Length=145, Percent_Identity=28.2758620689655, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 66367; Mature: 66367

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITELLTKHTIKLNLESSQKENVIEELVSVLDQAGKLNDKEGYKEAVINREKQSSTGIG
CCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCC
EGIAIPHAKTASVKEPAIAFGRSKGGVDYESLDGQPSHLVFMIAATDGANNTHLEALSRL
CCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHH
STLLMREEIRKQLLEASSEDEIIDIINQHDKDDDEEEEQAEEAPAPSAKGKILAVTACPT
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCC
GIAHTFMAADALKEKAKELGVDIKVETNGSSGIKNGLTAQEIEDAVAIIVAADKQVEMER
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHEEEEEECCCHHHHHH
FQGKHVIEVPVTAGIRRPQELIEQALKQDAPIYQGKGGGATASEDGAAKGKGGGFYKHLM
HCCCEEEEECCHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHH
SGVSNMLPFVVGGGILVAISFFWGINATKPGDPTYNEFAAVLNNIGGTNALGLIVAVLAG
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
FIAMSIADRPGFAPGMVGGFMATQAGAGFLGGLIAGFLAGYIVVLLKKVFAGLPQVLDGL
HHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
KPVLLYPLFGIFLTGIIMQYVVNTPVKYIMDGMTHWLEGLGTGNLVVMGIVLGGMMAIDM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEC
GGPINKAAFTFGIAMIEAGNFGPHAAIMAGGMVPPLGIALATTFFKNKFSKRDREAGITN
CCCCHHHHHHHHHHHEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YVMGLSFITEGAIPFAAADPARVIPACIIGSAVAGGLSQFFHVTLQAPHGGIFVLFFTTN
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEECC
HALLYLLSILIGAVVTALILGVLKKPVPTEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKITELLTKHTIKLNLESSQKENVIEELVSVLDQAGKLNDKEGYKEAVINREKQSSTGIG
CCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHCCCCCC
EGIAIPHAKTASVKEPAIAFGRSKGGVDYESLDGQPSHLVFMIAATDGANNTHLEALSRL
CCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHH
STLLMREEIRKQLLEASSEDEIIDIINQHDKDDDEEEEQAEEAPAPSAKGKILAVTACPT
HHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCC
GIAHTFMAADALKEKAKELGVDIKVETNGSSGIKNGLTAQEIEDAVAIIVAADKQVEMER
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHEEEEEECCCHHHHHH
FQGKHVIEVPVTAGIRRPQELIEQALKQDAPIYQGKGGGATASEDGAAKGKGGGFYKHLM
HCCCEEEEECCHHCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHH
SGVSNMLPFVVGGGILVAISFFWGINATKPGDPTYNEFAAVLNNIGGTNALGLIVAVLAG
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
FIAMSIADRPGFAPGMVGGFMATQAGAGFLGGLIAGFLAGYIVVLLKKVFAGLPQVLDGL
HHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
KPVLLYPLFGIFLTGIIMQYVVNTPVKYIMDGMTHWLEGLGTGNLVVMGIVLGGMMAIDM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEC
GGPINKAAFTFGIAMIEAGNFGPHAAIMAGGMVPPLGIALATTFFKNKFSKRDREAGITN
CCCCHHHHHHHHHHHEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YVMGLSFITEGAIPFAAADPARVIPACIIGSAVAGGLSQFFHVTLQAPHGGIFVLFFTTN
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEECC
HALLYLLSILIGAVVTALILGVLKKPVPTEK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]