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The map label for this gene is ptsG [H]

Identifier: 52785361

GI number: 52785361

Start: 1562001

End: 1564097

Strand: Direct

Name: ptsG [H]

Synonym: BLi01598

Alternate gene names: 52785361

Gene position: 1562001-1564097 (Clockwise)

Preceding gene: 52785360

Following gene: 52785362

Centisome position: 36.99

GC content: 48.69

Gene sequence:

>2097_bases
ATGTTTAAATCGCTATTTGGCGTTCTGCAAAAAATTGGACGAGCGCTGATGCTTCCTGTTGCCATCCTGCCGGCTGCAGG
GATTCTGCTCGCGCTTGGTAATGCCATGCAAAATCCGCAGATGACAAAAGTCGCACCATTCTTAACGAACAGCACCGTTC
AGCTTGTTGCGAAAGTGATGGAAAGTTCAGGTGACGTTGTGTTCACCAACTTGGCGCTCCTTTTCGCTGTCGGGGTTGCC
ATCGGTTTGGCTAACGGCGACGGCGTTGCCGGAATCGCTGCTATTATCGGATATCTTGTTATGAATGTCACGATGAGTGC
AGTGCTCCTTCAAAACGGTTCAATTCCAAGCGATGCAGTTGAAAGAGCACAGTTCTTTACTCAAAACCATCCGGAATACA
CGACAATGCTCGGGATACCGACATTGGCAACGGGAGTATTCGGGGGTATTATTGTCGGTGTCCTGGCCGCAGCCATGTAC
AATCGATTCTACACAATCGAGCTTCCGCAATATTTAGGATTCTTTGCCGGAAAGCGCTTTGTTCCGATTATTACATCTAT
TTGTGCATTGCTGCTGGGACTTGTTATGCTGTTTATCTGGCCGCCAATTCAAGGCGCACTGAACAGCTTTTCAACGAACC
TGCTTGCAGCCAATGAAGCGGTCGCAGCTCTCATCTTCGGAATGATTGAGCGGGCTCTGATTCCGTTCGGTCTGCACCAT
ATTTTCTACTCGCCGTTCTGGTATGAGTTCTTCAGCTATACGAACCAGGCGGGAGAAATTGTCCGCGGTGACCAAAGAAT
TTTCATGGCGCAAATCAAAGACGGCGTCGAATTGACAGCGGGTACATTTATGACCGGTAAGTATCCGTTCATGATGTTCG
GTCTTCCTGCGGCAGCGCTTGCCATTTATCATGAAGCAAAACCGCAGAACAAAAAGCTTGTTGCCGGTATTATGGGGTCA
GCAGCCTTAACATCATTCTTAACAGGGATCACTGAGCCGATCGAATTCTCATTCCTGTTCGTCGCACCGATTCTGTTTGC
GATTCACTGTGTGTTTGCCGGCCTGTCATTCATGATGATGGACATCTTGAATGTTAAGATCGGGATGACGTTCTCCGGCG
GTTTGATCGACTACTTCCTGTTCGGAATTCTGCCGAACCGTACAGCTTGGTGGCTTGTCATTCCTGTCGGTTTAGTCCTG
GCTGTCATCTACTACTTCGGATTCAGATTTGCCATCCGCAAGTTCAACTTGAAAACGCCTGGACGCGAAGATGCAGCTGC
AGAACCCGCTGATGAAGGCAAAGAAGCAGCAGGAGATCTTCCTTATCAAATTCTTGAAGCGATGGGTGACCAGGAAAATA
TCAAGCACCTTGACGCTTGTATCACAAGACTTCGCGTAACAGTCAACGATCAGAAGAAAGTTGACAAAGAGCGCTTGAAA
AAACTCGGCGCTTCCGGCGTGCTGGAAGTCGGCAATAACATCCAAGCGATATTCGGACCAAGATCCGACAATTTAAAATC
ACAAATGCAAGACATTATGTCAGGCCGGACGCCTCGTCCTGAAAAAGCGCCGAACGCTGCCGAGGAAGTGGAGCAGCAAA
TCGAAGAAGCTATGGTTGAGCCTCTTCAAAACGAATCAGGTGAAGAAGTATTCGTTTCACCGCTTGCGGGTGAACTTCAT
CCGATTGCAGATGTTCCGGACCAAGTATTCTCCGGAAAAATGATGGGTGACGGATTTGCGATTCTTCCTGCAGAAGGCAC
AGTTGTGTCACCTGTAAGAGGGAAAGTGCTGAACGTGTTCCCGACAAAGCATGCGATCGGTCTGCAGTCTGACGGCGGCA
GAGAAATTCTGATCCACTTTGGAATCGACACAGTCAGTCTGAAAGGAGAAGGCTTCACTTCATTTGTTTCTGAAGGTGAC
AGGGTTGAGCCTGGCCAGAAACTGCTTGAAGTCGACATTGAAAAAGTGAAGGACAATGTACCTTCCCTGATGACGCCGAT
CGTGTTCACGAACCTTCAAGAAGGAGAAAGCGTGAGCTTGCAGGCAGAAGGCAATGTCAGCCTGACACAGGACGACATCG
TCCGCATCGAAAAATAA

Upstream 100 bases:

>100_bases
GAAATGTAAACGGTTTATTTAGATGAAAAAGCAGTCTTTTGAACGAAGTTGTCATGAATTTTTGCTGTAAGGTCAAACTA
TTCTTAGAGGGGGTTAAAAA

Downstream 100 bases:

>100_bases
ATTCACAAAATGGCCGTACTTGTCAGATGACATGTACGGCTGTATGATATAATATTGTGAATGTACTCAAAGCTTTAAAT
TAAAAGGAGATTGATAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MFKSLFGVLQKIGRALMLPVAILPAAGILLALGNAMQNPQMTKVAPFLTNSTVQLVAKVMESSGDVVFTNLALLFAVGVA
IGLANGDGVAGIAAIIGYLVMNVTMSAVLLQNGSIPSDAVERAQFFTQNHPEYTTMLGIPTLATGVFGGIIVGVLAAAMY
NRFYTIELPQYLGFFAGKRFVPIITSICALLLGLVMLFIWPPIQGALNSFSTNLLAANEAVAALIFGMIERALIPFGLHH
IFYSPFWYEFFSYTNQAGEIVRGDQRIFMAQIKDGVELTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGS
AALTSFLTGITEPIEFSFLFVAPILFAIHCVFAGLSFMMMDILNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLVL
AVIYYFGFRFAIRKFNLKTPGREDAAAEPADEGKEAAGDLPYQILEAMGDQENIKHLDACITRLRVTVNDQKKVDKERLK
KLGASGVLEVGNNIQAIFGPRSDNLKSQMQDIMSGRTPRPEKAPNAAEEVEQQIEEAMVEPLQNESGEEVFVSPLAGELH
PIADVPDQVFSGKMMGDGFAILPAEGTVVSPVRGKVLNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGD
RVEPGQKLLEVDIEKVKDNVPSLMTPIVFTNLQEGESVSLQAEGNVSLTQDDIVRIEK

Sequences:

>Translated_698_residues
MFKSLFGVLQKIGRALMLPVAILPAAGILLALGNAMQNPQMTKVAPFLTNSTVQLVAKVMESSGDVVFTNLALLFAVGVA
IGLANGDGVAGIAAIIGYLVMNVTMSAVLLQNGSIPSDAVERAQFFTQNHPEYTTMLGIPTLATGVFGGIIVGVLAAAMY
NRFYTIELPQYLGFFAGKRFVPIITSICALLLGLVMLFIWPPIQGALNSFSTNLLAANEAVAALIFGMIERALIPFGLHH
IFYSPFWYEFFSYTNQAGEIVRGDQRIFMAQIKDGVELTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGS
AALTSFLTGITEPIEFSFLFVAPILFAIHCVFAGLSFMMMDILNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLVL
AVIYYFGFRFAIRKFNLKTPGREDAAAEPADEGKEAAGDLPYQILEAMGDQENIKHLDACITRLRVTVNDQKKVDKERLK
KLGASGVLEVGNNIQAIFGPRSDNLKSQMQDIMSGRTPRPEKAPNAAEEVEQQIEEAMVEPLQNESGEEVFVSPLAGELH
PIADVPDQVFSGKMMGDGFAILPAEGTVVSPVRGKVLNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGD
RVEPGQKLLEVDIEKVKDNVPSLMTPIVFTNLQEGESVSLQAEGNVSLTQDDIVRIEK
>Mature_698_residues
MFKSLFGVLQKIGRALMLPVAILPAAGILLALGNAMQNPQMTKVAPFLTNSTVQLVAKVMESSGDVVFTNLALLFAVGVA
IGLANGDGVAGIAAIIGYLVMNVTMSAVLLQNGSIPSDAVERAQFFTQNHPEYTTMLGIPTLATGVFGGIIVGVLAAAMY
NRFYTIELPQYLGFFAGKRFVPIITSICALLLGLVMLFIWPPIQGALNSFSTNLLAANEAVAALIFGMIERALIPFGLHH
IFYSPFWYEFFSYTNQAGEIVRGDQRIFMAQIKDGVELTAGTFMTGKYPFMMFGLPAAALAIYHEAKPQNKKLVAGIMGS
AALTSFLTGITEPIEFSFLFVAPILFAIHCVFAGLSFMMMDILNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLVL
AVIYYFGFRFAIRKFNLKTPGREDAAAEPADEGKEAAGDLPYQILEAMGDQENIKHLDACITRLRVTVNDQKKVDKERLK
KLGASGVLEVGNNIQAIFGPRSDNLKSQMQDIMSGRTPRPEKAPNAAEEVEQQIEEAMVEPLQNESGEEVFVSPLAGELH
PIADVPDQVFSGKMMGDGFAILPAEGTVVSPVRGKVLNVFPTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGD
RVEPGQKLLEVDIEKVKDNVPSLMTPIVFTNLQEGESVSLQAEGNVSLTQDDIVRIEK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=511, Percent_Identity=47.3581213307241, Blast_Score=441, Evalue=1e-124,
Organism=Escherichia coli, GI1786894, Length=720, Percent_Identity=35.6944444444444, Blast_Score=417, Evalue=1e-117,
Organism=Escherichia coli, GI1787908, Length=525, Percent_Identity=37.5238095238095, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI1788757, Length=163, Percent_Identity=38.6503067484663, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1790159, Length=157, Percent_Identity=37.5796178343949, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 75628; Mature: 75628

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSLFGVLQKIGRALMLPVAILPAAGILLALGNAMQNPQMTKVAPFLTNSTVQLVAKVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
ESSGDVVFTNLALLFAVGVAIGLANGDGVAGIAAIIGYLVMNVTMSAVLLQNGSIPSDAV
HCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ERAQFFTQNHPEYTTMLGIPTLATGVFGGIIVGVLAAAMYNRFYTIELPQYLGFFAGKRF
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCHH
VPIITSICALLLGLVMLFIWPPIQGALNSFSTNLLAANEAVAALIFGMIERALIPFGLHH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFYSPFWYEFFSYTNQAGEIVRGDQRIFMAQIKDGVELTAGTFMTGKYPFMMFGLPAAAL
HHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHCCCCEEECCEEECCCCCHHHHHHHHHHH
AIYHEAKPQNKKLVAGIMGSAALTSFLTGITEPIEFSFLFVAPILFAIHCVFAGLSFMMM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLVLAVIYYFGFRFAIRKFNLKTP
HHHHHHCCEEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GREDAAAEPADEGKEAAGDLPYQILEAMGDQENIKHLDACITRLRVTVNDQKKVDKERLK
CCCCCCCCCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHH
KLGASGVLEVGNNIQAIFGPRSDNLKSQMQDIMSGRTPRPEKAPNAAEEVEQQIEEAMVE
HCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
PLQNESGEEVFVSPLAGELHPIADVPDQVFSGKMMGDGFAILPAEGTVVSPVRGKVLNVF
HHCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCEECCCCCCEEEEE
PTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGDRVEPGQKLLEVDIEKVKDNV
CCCCCCCCCCCCCCEEEEEECCEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
PSLMTPIVFTNLQEGESVSLQAEGNVSLTQDDIVRIEK
HHHHHHHHHCCCCCCCEEEEEECCCCEECHHCCCEECC
>Mature Secondary Structure
MFKSLFGVLQKIGRALMLPVAILPAAGILLALGNAMQNPQMTKVAPFLTNSTVQLVAKVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
ESSGDVVFTNLALLFAVGVAIGLANGDGVAGIAAIIGYLVMNVTMSAVLLQNGSIPSDAV
HCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
ERAQFFTQNHPEYTTMLGIPTLATGVFGGIIVGVLAAAMYNRFYTIELPQYLGFFAGKRF
HHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHCCCHH
VPIITSICALLLGLVMLFIWPPIQGALNSFSTNLLAANEAVAALIFGMIERALIPFGLHH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFYSPFWYEFFSYTNQAGEIVRGDQRIFMAQIKDGVELTAGTFMTGKYPFMMFGLPAAAL
HHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHCCCCEEECCEEECCCCCHHHHHHHHHHH
AIYHEAKPQNKKLVAGIMGSAALTSFLTGITEPIEFSFLFVAPILFAIHCVFAGLSFMMM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILNVKIGMTFSGGLIDYFLFGILPNRTAWWLVIPVGLVLAVIYYFGFRFAIRKFNLKTP
HHHHHHCCEEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GREDAAAEPADEGKEAAGDLPYQILEAMGDQENIKHLDACITRLRVTVNDQKKVDKERLK
CCCCCCCCCCCCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHHH
KLGASGVLEVGNNIQAIFGPRSDNLKSQMQDIMSGRTPRPEKAPNAAEEVEQQIEEAMVE
HCCCCCHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
PLQNESGEEVFVSPLAGELHPIADVPDQVFSGKMMGDGFAILPAEGTVVSPVRGKVLNVF
HHCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCEECCCCCCEEEEE
PTKHAIGLQSDGGREILIHFGIDTVSLKGEGFTSFVSEGDRVEPGQKLLEVDIEKVKDNV
CCCCCCCCCCCCCCEEEEEECCEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
PSLMTPIVFTNLQEGESVSLQAEGNVSLTQDDIVRIEK
HHHHHHHHHCCCCCCCEEEEEECCCCEECHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]