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The map label for this gene is ykvZ [H]

Identifier: 52785359

GI number: 52785359

Start: 1559829

End: 1560800

Strand: Direct

Name: ykvZ [H]

Synonym: BLi01596

Alternate gene names: 52785359

Gene position: 1559829-1560800 (Clockwise)

Preceding gene: 52785358

Following gene: 52785360

Centisome position: 36.94

GC content: 48.35

Gene sequence:

>972_bases
ATGGCAAATATCAGGGAAATAGCTGAAGCGGCAGGGGTTTCCATCACGACTGTTTCGAGGGTTCTCAACGGCCACCCGTA
TGTCAAAGAAGAAAAGCGTCAAAAAGTTCTTGAGACGATTGAACGCCTCGAATATGCAAGGAATATGCATGCCGTTCATT
TATCCAAAGGCTTTTCCAACATGATAGGCGTTGTGCTGCCGACCATCAGCCTTCCTTATTTCGGCGAGCTGCTGGAAGGA
ATCGCTGAAGAAGCTGCGAAGGAAGGCGTTCACTTTTCGCTTTACCAAACAAATTATCAATTGGAAAAAGAAATTTTTGC
ATTGGAGCAGCTGAAACAAAGACAGGTGGACGGCCTGATTTTCTGTTCAAAAGCGATGTCCGATGAAGCGCTTTTGGACT
GGCGTGAAACCGGCCCGTTCATCCTGTGCCAGGACTCAGGCGAGCAGCACTTTGCAACGGTCAGCATTCCGCATAAAGAA
GCATTCAGACTTGGATTGGATTTTTTAATTGAAAAAGGGCACACAAAAATCGCGATTGGTTTGGCAAGGAAAAACGGCAT
GAACAGCCATTTTCGCCTCAAGGCATACAAGGAAGCTTTGGCCGCGATCGGGGAGCCTTACCGGGAAGAGTGGGTATTTG
AGCGGTCGCTGACAATTACCGACGGGCAAAAACTGTTCTCCGAATGGAAAGGGATGGAGGAGAAGCCGACGGCTGTTTTT
GTCGCAAACGACCAAGTATCAGCCGGTATTTTTCTTGAAGCGCAGCGGCATCAAGTGGATATTCCCGGAAGCCTCGCTAT
TTTAAGCTGTGACAACCAGCCGATCAGCGAAGTGCTCGGCATTTCAACAATTGAAATCAATATAAAGGAAATGGGGAAGC
GCGCGTTTCGCCTTCTGCAAAAAAGAATCGGCGGCGCCGGGCCGGAAAAACTGACTGTTCCTTACAAGCTGATCAAAAGG
GCGACTGTGTAA

Upstream 100 bases:

>100_bases
TGGCCAAAAGGATCAAAATCTATGGCTCAAAGCGATATAATTTCTTTATGATGAAATGATCCGGATGTGCGAAAAGATTT
GAATGAAAGAAGGGAAACGA

Downstream 100 bases:

>100_bases
TCAAAACATCAATCTTTTTCCAGACAGTGATCAAAATTCGACATTTTTCATCAAAAACGTCAAAATAAATTGACGCGCTT
TCATGAGTTTTGTACGATAT

Product: YkvZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MANIREIAEAAGVSITTVSRVLNGHPYVKEEKRQKVLETIERLEYARNMHAVHLSKGFSNMIGVVLPTISLPYFGELLEG
IAEEAAKEGVHFSLYQTNYQLEKEIFALEQLKQRQVDGLIFCSKAMSDEALLDWRETGPFILCQDSGEQHFATVSIPHKE
AFRLGLDFLIEKGHTKIAIGLARKNGMNSHFRLKAYKEALAAIGEPYREEWVFERSLTITDGQKLFSEWKGMEEKPTAVF
VANDQVSAGIFLEAQRHQVDIPGSLAILSCDNQPISEVLGISTIEINIKEMGKRAFRLLQKRIGGAGPEKLTVPYKLIKR
ATV

Sequences:

>Translated_323_residues
MANIREIAEAAGVSITTVSRVLNGHPYVKEEKRQKVLETIERLEYARNMHAVHLSKGFSNMIGVVLPTISLPYFGELLEG
IAEEAAKEGVHFSLYQTNYQLEKEIFALEQLKQRQVDGLIFCSKAMSDEALLDWRETGPFILCQDSGEQHFATVSIPHKE
AFRLGLDFLIEKGHTKIAIGLARKNGMNSHFRLKAYKEALAAIGEPYREEWVFERSLTITDGQKLFSEWKGMEEKPTAVF
VANDQVSAGIFLEAQRHQVDIPGSLAILSCDNQPISEVLGISTIEINIKEMGKRAFRLLQKRIGGAGPEKLTVPYKLIKR
ATV
>Mature_322_residues
ANIREIAEAAGVSITTVSRVLNGHPYVKEEKRQKVLETIERLEYARNMHAVHLSKGFSNMIGVVLPTISLPYFGELLEGI
AEEAAKEGVHFSLYQTNYQLEKEIFALEQLKQRQVDGLIFCSKAMSDEALLDWRETGPFILCQDSGEQHFATVSIPHKEA
FRLGLDFLIEKGHTKIAIGLARKNGMNSHFRLKAYKEALAAIGEPYREEWVFERSLTITDGQKLFSEWKGMEEKPTAVFV
ANDQVSAGIFLEAQRHQVDIPGSLAILSCDNQPISEVLGISTIEINIKEMGKRAFRLLQKRIGGAGPEKLTVPYKLIKRA
TV

Specific function: Repressor Of The Mgl Operon. Binds Galactose And D-Fucose As Inducers. Gals Binds To An Operator DNA Sequence Within Its Own Coding Sequence (Corresponding To Residues 15 To 20). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788474, Length=314, Percent_Identity=28.6624203821656, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787580, Length=325, Percent_Identity=30.1538461538462, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790369, Length=308, Percent_Identity=25.6493506493506, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1789202, Length=279, Percent_Identity=28.3154121863799, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787948, Length=338, Percent_Identity=27.2189349112426, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=24.8427672955975, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1789068, Length=331, Percent_Identity=26.8882175226586, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789456, Length=338, Percent_Identity=26.3313609467456, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=26.791277258567, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786540, Length=331, Percent_Identity=24.773413897281, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786268, Length=288, Percent_Identity=22.9166666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=24.3161094224924, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36244; Mature: 36113

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIREIAEAAGVSITTVSRVLNGHPYVKEEKRQKVLETIERLEYARNMHAVHLSKGFSN
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
MIGVVLPTISLPYFGELLEGIAEEAAKEGVHFSLYQTNYQLEKEIFALEQLKQRQVDGLI
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEE
FCSKAMSDEALLDWRETGPFILCQDSGEQHFATVSIPHKEAFRLGLDFLIEKGHTKIAIG
EEHHHCCCHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEE
LARKNGMNSHFRLKAYKEALAAIGEPYREEWVFERSLTITDGQKLFSEWKGMEEKPTAVF
EECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCEEEECCHHHHHHHHCCCCCCCCEEE
VANDQVSAGIFLEAQRHQVDIPGSLAILSCDNQPISEVLGISTIEINIKEMGKRAFRLLQ
EECCCCCCCEEEEECCCEECCCCCEEEEECCCCCHHHHHCCEEEEEEHHHHHHHHHHHHH
KRIGGAGPEKLTVPYKLIKRATV
HHHCCCCCCCEEHHHHHHHHCCC
>Mature Secondary Structure 
ANIREIAEAAGVSITTVSRVLNGHPYVKEEKRQKVLETIERLEYARNMHAVHLSKGFSN
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
MIGVVLPTISLPYFGELLEGIAEEAAKEGVHFSLYQTNYQLEKEIFALEQLKQRQVDGLI
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEE
FCSKAMSDEALLDWRETGPFILCQDSGEQHFATVSIPHKEAFRLGLDFLIEKGHTKIAIG
EEHHHCCCHHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEE
LARKNGMNSHFRLKAYKEALAAIGEPYREEWVFERSLTITDGQKLFSEWKGMEEKPTAVF
EECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCEEEECCHHHHHHHHCCCCCCCCEEE
VANDQVSAGIFLEAQRHQVDIPGSLAILSCDNQPISEVLGISTIEINIKEMGKRAFRLLQ
EECCCCCCCEEEEECCCEECCCCCEEEEECCCCCHHHHHCCEEEEEEHHHHHHHHHHHHH
KRIGGAGPEKLTVPYKLIKRATV
HHHCCCCCCCEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]