Click here to switch to the map view.

The map label for this gene is ykvM [H]

Identifier: 52785295

GI number: 52785295

Start: 1503738

End: 1504238

Strand: Direct

Name: ykvM [H]

Synonym: BLi01530

Alternate gene names: 52785295

Gene position: 1503738-1504238 (Clockwise)

Preceding gene: 52785294

Following gene: 52785296

Centisome position: 35.61

GC content: 45.31

Gene sequence:

>501_bases
ATGATGACGACAAGAAAAGATTCAGAACTGGAAGGCGTAACCCTTCTTGGAAATCAAGGCACCAATTATTTGTTTGACTA
TTCTCCGGAAGTGCTTGAGTCTTTCCCGAATAAACACGAAAACAGGGACTATTTCGTGAAATTCAACTGCCCTGAATTCA
CATCGCTGTGCCCGAAAACCGGACAGCCCGATTTTGCCACGATCTACATCAGCTACATCCCTGATAAAAAAATGGTAGAA
AGCAAGTCTTTGAAACTGTATCTCTTCAGTTTCCGAAACCACGGCGATTTTCACGAAGACTGCATGAACATCATCATGAA
CGATTTAATTGAGCTGATGGACCCGCGCTATATCGAAGTCTGGGGCAAATTCACGCCGAGGGGCGGAATCTCGATCGATC
CGTACACCAACTACGGCAAGCCCGGCACAAAGTATGAAAAAATGGCCGAGTATCGGATGATGAACCATGATCTGTATCCG
GAGACGATTGATAATCGGTGA

Upstream 100 bases:

>100_bases
CACGCGCGACCCTGAATTGAACCGCGTCCGCGTTCTCCCGCAGCTCCACACCCTGATCTGGGGAAACAAACGGGGTGTTT
GATTTAAGAAAGGAAGATGA

Downstream 100 bases:

>100_bases
TGATGAAGCGAAGGTTTGTGGTCGATGTGTGACCGGTCACAGTAAAAGTGTGACTCGGGTGTGACCCGAAAATAGCGAAG
TGTGACCCGTGAAAATACGG

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MMTTRKDSELEGVTLLGNQGTNYLFDYSPEVLESFPNKHENRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDKKMVE
SKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYP
ETIDNR

Sequences:

>Translated_166_residues
MMTTRKDSELEGVTLLGNQGTNYLFDYSPEVLESFPNKHENRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDKKMVE
SKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYP
ETIDNR
>Mature_166_residues
MMTTRKDSELEGVTLLGNQGTNYLFDYSPEVLESFPNKHENRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPDKKMVE
SKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEVWGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYP
ETIDNR

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789158, Length=81, Percent_Identity=38.2716049382716, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 19537; Mature: 19537

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTRKDSELEGVTLLGNQGTNYLFDYSPEVLESFPNKHENRDYFVKFNCPEFTSLCPKT
CCCCCCCCCCCCEEEECCCCCCEEEECCHHHHHHCCCCCCCCCEEEEECCCHHHHCCCCC
GQPDFATIYISYIPDKKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEV
CCCCEEEEEEEECCCCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEE
WGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPETIDNR
EECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMTTRKDSELEGVTLLGNQGTNYLFDYSPEVLESFPNKHENRDYFVKFNCPEFTSLCPKT
CCCCCCCCCCCCEEEECCCCCCEEEECCHHHHHHCCCCCCCCCEEEEECCCHHHHCCCCC
GQPDFATIYISYIPDKKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPRYIEV
CCCCEEEEEEEECCCCHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEE
WGKFTPRGGISIDPYTNYGKPGTKYEKMAEYRMMNHDLYPETIDNR
EECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA