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The map label for this gene is ykvL [H]

Identifier: 52785294

GI number: 52785294

Start: 1502988

End: 1503719

Strand: Direct

Name: ykvL [H]

Synonym: BLi01529

Alternate gene names: 52785294

Gene position: 1502988-1503719 (Clockwise)

Preceding gene: 52785293

Following gene: 52785295

Centisome position: 35.59

GC content: 50.14

Gene sequence:

>732_bases
ATGGCTAAGCCGATTCCCGTACTTGAAATTTTCGGTCCGACGGTTCAGGGAGAGGGGATGGTCATCGGCCAAAAGACGAT
GTTTGTCAGAACAGCCGGCTGTGACTATTCGTGCAGCTGGTGCGATTCAGCTTTTACCTGGGACGGTTCGGCGAAAAAAG
ACATCAAATGGATGACCGCGGAAGAAGTGTACGAATCTCTTAAAGACATCGGCGGAAACGCATTCTCGCACGTTACGATT
TCAGGAGGCAACCCGGCGCTTTTAAAACAGCTGGACGGACTGATTTCCCTTTTAAAAGAAAACGGTATACGGACAGCGCT
TGAGACGCAAGGAACGTTTTATCAAGACTGGTTTACCGGAATCGATGATTTAACAATTTCGCCAAAGCCGCCGAGCTCCA
ATATGAAAACCGATTTTAACAGGCTTGATCATATTGTTGACAGGCTGAAGGAACACGGCCGGGCGGCTGCGGCAAGTTTG
AAGGTCGTCATTTTCACGGCGGACGACCTTCAATTTGCAAAACAAGTTCACCAGCGTTATCCCGATATCCCGTTTTTTCT
TCAGGTCGGAAATGATGACGTTCATACAGAAGACCAAGAGCGGCTCGTCGAACGGCTGCTCCAAAAATATGAACAGCTGG
TAGAAGCGGTCACGCGCGACCCTGAATTGAACCGCGTCCGCGTTCTCCCGCAGCTCCACACCCTGATCTGGGGAAACAAA
CGGGGTGTTTGA

Upstream 100 bases:

>100_bases
TATTTGAAAGATCTCAACAACCGTCCGCATTGCGTCCAGGTGTTTGTCAGGGAAACGCCGACAAGCTATGTCGTGTACCG
TCCGAAACCGGGTGTTCAGC

Downstream 100 bases:

>100_bases
TTTAAGAAAGGAAGATGAATGATGACGACAAGAAAAGATTCAGAACTGGAAGGCGTAACCCTTCTTGGAAATCAAGGCAC
CAATTATTTGTTTGACTATT

Product: YkvL

Products: NA

Alternate protein names: CDG synthase; Queuosine biosynthesis protein queE [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MAKPIPVLEIFGPTVQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIKWMTAEEVYESLKDIGGNAFSHVTI
SGGNPALLKQLDGLISLLKENGIRTALETQGTFYQDWFTGIDDLTISPKPPSSNMKTDFNRLDHIVDRLKEHGRAAAASL
KVVIFTADDLQFAKQVHQRYPDIPFFLQVGNDDVHTEDQERLVERLLQKYEQLVEAVTRDPELNRVRVLPQLHTLIWGNK
RGV

Sequences:

>Translated_243_residues
MAKPIPVLEIFGPTVQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIKWMTAEEVYESLKDIGGNAFSHVTI
SGGNPALLKQLDGLISLLKENGIRTALETQGTFYQDWFTGIDDLTISPKPPSSNMKTDFNRLDHIVDRLKEHGRAAAASL
KVVIFTADDLQFAKQVHQRYPDIPFFLQVGNDDVHTEDQERLVERLLQKYEQLVEAVTRDPELNRVRVLPQLHTLIWGNK
RGV
>Mature_242_residues
AKPIPVLEIFGPTVQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIKWMTAEEVYESLKDIGGNAFSHVTIS
GGNPALLKQLDGLISLLKENGIRTALETQGTFYQDWFTGIDDLTISPKPPSSNMKTDFNRLDHIVDRLKEHGRAAAASLK
VVIFTADDLQFAKQVHQRYPDIPFFLQVGNDDVHTEDQERLVERLLQKYEQLVEAVTRDPELNRVRVLPQLHTLIWGNKR
GV

Specific function: Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) [H]

COG id: COG0602

COG function: function code O; Organic radical activating enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. 7-carboxy-7- deazaguanine synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789139, Length=161, Percent_Identity=32.2981366459627, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017742
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 27337; Mature: 27206

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPIPVLEIFGPTVQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIKWMTA
CCCCCCCCEECCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCEECCCCCCCCEEECCH
EEVYESLKDIGGNAFSHVTISGGNPALLKQLDGLISLLKENGIRTALETQGTFYQDWFTG
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHHHHCC
IDDLTISPKPPSSNMKTDFNRLDHIVDRLKEHGRAAAASLKVVIFTADDLQFAKQVHQRY
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCEEEEEEEECCHHHHHHHHHHHC
PDIPFFLQVGNDDVHTEDQERLVERLLQKYEQLVEAVTRDPELNRVRVLPQLHTLIWGNK
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCC
RGV
CCC
>Mature Secondary Structure 
AKPIPVLEIFGPTVQGEGMVIGQKTMFVRTAGCDYSCSWCDSAFTWDGSAKKDIKWMTA
CCCCCCCEECCCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCEECCCCCCCCEEECCH
EEVYESLKDIGGNAFSHVTISGGNPALLKQLDGLISLLKENGIRTALETQGTFYQDWFTG
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEHHCCCCCHHHHHCC
IDDLTISPKPPSSNMKTDFNRLDHIVDRLKEHGRAAAASLKVVIFTADDLQFAKQVHQRY
CCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCEEEEEEEECCHHHHHHHHHHHC
PDIPFFLQVGNDDVHTEDQERLVERLLQKYEQLVEAVTRDPELNRVRVLPQLHTLIWGNK
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCC
RGV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]