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The map label for this gene is ykrV [H]

Identifier: 52785279

GI number: 52785279

Start: 1488465

End: 1489655

Strand: Direct

Name: ykrV [H]

Synonym: BLi01514

Alternate gene names: 52785279

Gene position: 1488465-1489655 (Clockwise)

Preceding gene: 52785275

Following gene: 52785280

Centisome position: 35.25

GC content: 53.65

Gene sequence:

>1191_bases
ATGAAATTTGAGCATTCAGATGTACTGAAGCAGCTGCCGGAGCAGTTTTTCGCTTCCTTGGTCAAAAAGGTGAATGAAAA
AATTGCCGCCGGCCATGATGTCATCAATCTCGGTCAGGGGAATCCGGATCAGCCGACACCGGAACATATCGTTGATACAA
TGGCGCAAGCCGTCCGCAACCCTGAAAACCACCGGTATTCTTCCTTTCGCGGCAGCCGTTCACTCAAGGAGGCGGCGGCC
GCGTTCTATCAAAGGGAATACGGCGTAGAGCTCGATCCTGAACGCGAAGTCGCTGTATTGTTCGGCGGAAAAGCCGGTCT
TGTCGAACTTCCGCAATGTTTGTTAAATCCGGGGGATACAGTGCTCGTTCCCGATCCCGGCTATCCCGACTACTGGTCGG
GCGTTGAACTGGCAAGAGCGAACATGGAAACGATGCCGCTTACAGCGGACAATCAGTTTCTGCCTGACTACAGCCGGATT
CCCAAGGAAGTGAAAGAAAAAGCGAAGCTCATGTATTTAAATTATCCGAACAACCCGACCGGTGCCCAAGCCACATCTGC
TTTTTTCGAAGAGACCGTCCGGTTTGCCAAGTCGAACGGAATTTGCGTCGTCCATGATTTTGCCTACGGCGCGATCGGCT
ACGACGGCAAGAGGCCTGTCAGCTTTCTCGAAACGGCGGGAGCAAAAGACGCAGGAATCGAAATTTACACGCTTTCCAAA
ACGTATAATATGGCTGGATGGCGGGTCGGGTTTGCAGTCGGCAACGCCTCTGTGATCGAAGCGCTGAACCTTTACCAGGA
CCATATGTATGTCAGCCTCTTTAAAGCAGTCCAAGACGCCGCGGCGGCCGCGCTCCTATCAGATCAAGCGTGTGTCCAGG
AGCAAAATGAGCGCTACGAAAAAAGGCGGAATGCATGGATCCGCGCGGTCCGCGATATCGGCTGGCATGCGGATGCTCCG
CAAGGATCTTTTTTCGCCTGGATGCCTGTTCCCGACGGCTATACATCTGAGGCTTTTTCCGATCTGCTTCTCGAAAAAGC
GAATGTCGTCACCGCGCCCGGCATCGGCTTCGGCAAACACGGGGAAGGCTATGTGAGAGTCGGCCTCTTGACAAGCGAAG
AGCGGCTCCGGGAAGCGGCTTCGCGTATTGCCGAGCTGAATATATTCAAAAAGACCGGCCACAGTCATTGA

Upstream 100 bases:

>100_bases
TTCACTCTGGATCACCTCATTTTTTTCTTTACATTTTACATTTAACAATATATGATGATGGACTATCATTTCAAGAATTT
TTCAAAAGCGGGTGAATCGT

Downstream 100 bases:

>100_bases
CAACCGGGAGAAACGATGGGATAATTCAAAATAATTTATAAAATCAATATTCTTATCAAGAGCAGGCAGAGGGACAAGCC
CGATGAAGCCCGGCAACCGA

Product: transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKFEHSDVLKQLPEQFFASLVKKVNEKIAAGHDVINLGQGNPDQPTPEHIVDTMAQAVRNPENHRYSSFRGSRSLKEAAA
AFYQREYGVELDPEREVAVLFGGKAGLVELPQCLLNPGDTVLVPDPGYPDYWSGVELARANMETMPLTADNQFLPDYSRI
PKEVKEKAKLMYLNYPNNPTGAQATSAFFEETVRFAKSNGICVVHDFAYGAIGYDGKRPVSFLETAGAKDAGIEIYTLSK
TYNMAGWRVGFAVGNASVIEALNLYQDHMYVSLFKAVQDAAAAALLSDQACVQEQNERYEKRRNAWIRAVRDIGWHADAP
QGSFFAWMPVPDGYTSEAFSDLLLEKANVVTAPGIGFGKHGEGYVRVGLLTSEERLREAASRIAELNIFKKTGHSH

Sequences:

>Translated_396_residues
MKFEHSDVLKQLPEQFFASLVKKVNEKIAAGHDVINLGQGNPDQPTPEHIVDTMAQAVRNPENHRYSSFRGSRSLKEAAA
AFYQREYGVELDPEREVAVLFGGKAGLVELPQCLLNPGDTVLVPDPGYPDYWSGVELARANMETMPLTADNQFLPDYSRI
PKEVKEKAKLMYLNYPNNPTGAQATSAFFEETVRFAKSNGICVVHDFAYGAIGYDGKRPVSFLETAGAKDAGIEIYTLSK
TYNMAGWRVGFAVGNASVIEALNLYQDHMYVSLFKAVQDAAAAALLSDQACVQEQNERYEKRRNAWIRAVRDIGWHADAP
QGSFFAWMPVPDGYTSEAFSDLLLEKANVVTAPGIGFGKHGEGYVRVGLLTSEERLREAASRIAELNIFKKTGHSH
>Mature_396_residues
MKFEHSDVLKQLPEQFFASLVKKVNEKIAAGHDVINLGQGNPDQPTPEHIVDTMAQAVRNPENHRYSSFRGSRSLKEAAA
AFYQREYGVELDPEREVAVLFGGKAGLVELPQCLLNPGDTVLVPDPGYPDYWSGVELARANMETMPLTADNQFLPDYSRI
PKEVKEKAKLMYLNYPNNPTGAQATSAFFEETVRFAKSNGICVVHDFAYGAIGYDGKRPVSFLETAGAKDAGIEIYTLSK
TYNMAGWRVGFAVGNASVIEALNLYQDHMYVSLFKAVQDAAAAALLSDQACVQEQNERYEKRRNAWIRAVRDIGWHADAP
QGSFFAWMPVPDGYTSEAFSDLLLEKANVVTAPGIGFGKHGEGYVRVGLLTSEERLREAASRIAELNIFKKTGHSH

Specific function: Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB) (Probable) [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. MtnE subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=23.8693467336683, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=23.8693467336683, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI56713256, Length=315, Percent_Identity=24.4444444444444, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI56713254, Length=315, Percent_Identity=24.4444444444444, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1788722, Length=359, Percent_Identity=39.8328690807799, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=24.2424242424242, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=345, Percent_Identity=26.3768115942029, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=270, Percent_Identity=28.8888888888889, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=270, Percent_Identity=28.8888888888889, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=336, Percent_Identity=21.4285714285714, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=21.5736040609137, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=23.3576642335766, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=23.3576642335766, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=23.3576642335766, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=23.3576642335766, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43820; Mature: 43820

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFEHSDVLKQLPEQFFASLVKKVNEKIAAGHDVINLGQGNPDQPTPEHIVDTMAQAVRN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHCC
PENHRYSSFRGSRSLKEAAAAFYQREYGVELDPEREVAVLFGGKAGLVELPQCLLNPGDT
CCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCE
VLVPDPGYPDYWSGVELARANMETMPLTADNQFLPDYSRIPKEVKEKAKLMYLNYPNNPT
EEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHCCHHHHHCCEEEEEECCCCCC
GAQATSAFFEETVRFAKSNGICVVHDFAYGAIGYDGKRPVSFLETAGAKDAGIEIYTLSK
CHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECC
TYNMAGWRVGFAVGNASVIEALNLYQDHMYVSLFKAVQDAAAAALLSDQACVQEQNERYE
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRNAWIRAVRDIGWHADAPQGSFFAWMPVPDGYTSEAFSDLLLEKANVVTAPGIGFGKH
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCCC
GEGYVRVGLLTSEERLREAASRIAELNIFKKTGHSH
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFEHSDVLKQLPEQFFASLVKKVNEKIAAGHDVINLGQGNPDQPTPEHIVDTMAQAVRN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHCC
PENHRYSSFRGSRSLKEAAAAFYQREYGVELDPEREVAVLFGGKAGLVELPQCLLNPGDT
CCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCE
VLVPDPGYPDYWSGVELARANMETMPLTADNQFLPDYSRIPKEVKEKAKLMYLNYPNNPT
EEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHCCHHHHHCCEEEEEECCCCCC
GAQATSAFFEETVRFAKSNGICVVHDFAYGAIGYDGKRPVSFLETAGAKDAGIEIYTLSK
CHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECC
TYNMAGWRVGFAVGNASVIEALNLYQDHMYVSLFKAVQDAAAAALLSDQACVQEQNERYE
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRRNAWIRAVRDIGWHADAPQGSFFAWMPVPDGYTSEAFSDLLLEKANVVTAPGIGFGKH
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCCC
GEGYVRVGLLTSEERLREAASRIAELNIFKKTGHSH
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]