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The map label for this gene is uppP

Identifier: 52784985

GI number: 52784985

Start: 1225984

End: 1226796

Strand: Reverse

Name: uppP

Synonym: BLi01213

Alternate gene names: 52784985

Gene position: 1226796-1225984 (Counterclockwise)

Preceding gene: 52784987

Following gene: 52784975

Centisome position: 29.05

GC content: 45.14

Gene sequence:

>813_bases
ATGGATTTTTTAGTGTTGATCAAGTATATCCTTTTAGGGTTGCTTCAGGGATTCACAGAGCCGATCCCTGTTTCGTCAAG
CGGCCATTTGGTGCTGGCACAGCACTTTTTGGGCTTGAATATTGAAGGCTTCAGTTTTGAGCTTTTGATGAATGCCGGTT
CTTTAATTGCCGTACTGCTCGTTTATAAAAACGATATTTTCAGGCTGGCGGTAAACGGGCTGTCTTATGTCACAACAAAA
AATGAAAAAGGAAAAGCGGACTTCAGGTTTATCATCTATCTGATCATCGCCACGATTCCTGCCGGTGTCATCGGCGTTTT
ATTTGATGATGAGATTTCGGCTTTCTTTAAAGACGGCGTCCGGATCACCGCGGTTACTTTGCTTATTACGGGTCTGGCAT
TGTTTCTTATTCGAAATTTGCGCGGCCGGAAAAGCGACGGCGAAATCAGGCTGAGAGACGCCGTGATCATCGGCTTTTCG
CAAATGGTTGCACTTGTTCCCGGCATCAGCCGTTCGGGAGCGACGATCGTTCCTGCGATGGCGCTCGGCCTCAAATCTGA
AACCGCGCTCAGGTTTTCATTTTTGCTTTACATACCGGTCAGCCTTGGCGGAACCATTTTAAGCATTACCGATATTTTTC
ATGATCCGCGTTTAGGAGAGCTTTTTCTTCCTTATTTATTCGCGTTCATCGCATCTGTTATAGCTACATACTTCTCATTG
CGCTGGTTCATGAATATTATGGCGAAAGGAAACTTGGTTTATTTCTCGATTTACTGCTTTGTCATCGGCATCGCCGTTTT
GATATTCGCCTAA

Upstream 100 bases:

>100_bases
TGTAGTTTAATGAGAAAAGCGTTCTGAAAATTGAAACGAACCGCCTGTACATTCCGTCTGTTAAAAGGGCATCACAACTT
GTGGGAAACGGAGGAGTATC

Downstream 100 bases:

>100_bases
AAACAGCTGATCAATGGATCAGCTGTTTTTCATTTAAGATAACAGTGCTTTTAATAAAGCTTTTTGGACGTGCAGGCGGT
TTTCAGCCTGCTGAAATACC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDFLVLIKYILLGLLQGFTEPIPVSSSGHLVLAQHFLGLNIEGFSFELLMNAGSLIAVLLVYKNDIFRLAVNGLSYVTTK
NEKGKADFRFIIYLIIATIPAGVIGVLFDDEISAFFKDGVRITAVTLLITGLALFLIRNLRGRKSDGEIRLRDAVIIGFS
QMVALVPGISRSGATIVPAMALGLKSETALRFSFLLYIPVSLGGTILSITDIFHDPRLGELFLPYLFAFIASVIATYFSL
RWFMNIMAKGNLVYFSIYCFVIGIAVLIFA

Sequences:

>Translated_270_residues
MDFLVLIKYILLGLLQGFTEPIPVSSSGHLVLAQHFLGLNIEGFSFELLMNAGSLIAVLLVYKNDIFRLAVNGLSYVTTK
NEKGKADFRFIIYLIIATIPAGVIGVLFDDEISAFFKDGVRITAVTLLITGLALFLIRNLRGRKSDGEIRLRDAVIIGFS
QMVALVPGISRSGATIVPAMALGLKSETALRFSFLLYIPVSLGGTILSITDIFHDPRLGELFLPYLFAFIASVIATYFSL
RWFMNIMAKGNLVYFSIYCFVIGIAVLIFA
>Mature_270_residues
MDFLVLIKYILLGLLQGFTEPIPVSSSGHLVLAQHFLGLNIEGFSFELLMNAGSLIAVLLVYKNDIFRLAVNGLSYVTTK
NEKGKADFRFIIYLIIATIPAGVIGVLFDDEISAFFKDGVRITAVTLLITGLALFLIRNLRGRKSDGEIRLRDAVIIGFS
QMVALVPGISRSGATIVPAMALGLKSETALRFSFLLYIPVSLGGTILSITDIFHDPRLGELFLPYLFAFIASVIATYFSL
RWFMNIMAKGNLVYFSIYCFVIGIAVLIFA

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=273, Percent_Identity=30.03663003663, Blast_Score=117, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_BACLD (Q65LE3)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_078413.1
- RefSeq:   YP_090814.1
- STRING:   Q65LE3
- EnsemblBacteria:   EBBACT00000057525
- EnsemblBacteria:   EBBACT00000062008
- GeneID:   3030205
- GeneID:   3100472
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01213
- KEGG:   bli:BL03255
- NMPDR:   fig|279010.5.peg.2382
- eggNOG:   COG1968
- GeneTree:   EBGT00050000002490
- HOGENOM:   HBG391969
- OMA:   FALLWYF
- ProtClustDB:   PRK12554
- BioCyc:   BLIC279010-1:BLI01213-MONOMER
- BioCyc:   BLIC279010:BL03255-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29693; Mature: 29693

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd27b264)-; HASH(0xe1038ec)-; HASH(0xd2b41dc)-; HASH(0xdebb4e0)-; HASH(0xcd68c6c)-; HASH(0xe0f42d0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLVLIKYILLGLLQGFTEPIPVSSSGHLVLAQHFLGLNIEGFSFELLMNAGSLIAVLL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHCCCCCCCEEEEECCCCHHHHHHH
VYKNDIFRLAVNGLSYVTTKNEKGKADFRFIIYLIIATIPAGVIGVLFDDEISAFFKDGV
HHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCHHHEEEEECHHHHHHHHCCC
RITAVTLLITGLALFLIRNLRGRKSDGEIRLRDAVIIGFSQMVALVPGISRSGATIVPAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHEEEECHHHHHHHCCCCCCCCCEEHHHH
ALGLKSETALRFSFLLYIPVSLGGTILSITDIFHDPRLGELFLPYLFAFIASVIATYFSL
HHCCCCCHHHHHHEEEEEHHHCCCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RWFMNIMAKGNLVYFSIYCFVIGIAVLIFA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MDFLVLIKYILLGLLQGFTEPIPVSSSGHLVLAQHFLGLNIEGFSFELLMNAGSLIAVLL
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHCCCCCCCEEEEECCCCHHHHHHH
VYKNDIFRLAVNGLSYVTTKNEKGKADFRFIIYLIIATIPAGVIGVLFDDEISAFFKDGV
HHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCHHHEEEEECHHHHHHHHCCC
RITAVTLLITGLALFLIRNLRGRKSDGEIRLRDAVIIGFSQMVALVPGISRSGATIVPAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHEEEECHHHHHHHCCCCCCCCCEEHHHH
ALGLKSETALRFSFLLYIPVSLGGTILSITDIFHDPRLGELFLPYLFAFIASVIATYFSL
HHCCCCCHHHHHHEEEEEHHHCCCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RWFMNIMAKGNLVYFSIYCFVIGIAVLIFA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA