Click here to switch to the map view.

The map label for this gene is yerA [H]

Identifier: 52784511

GI number: 52784511

Start: 713988

End: 715727

Strand: Direct

Name: yerA [H]

Synonym: BLi00711

Alternate gene names: 52784511

Gene position: 713988-715727 (Clockwise)

Preceding gene: 52784509

Following gene: 52784512

Centisome position: 16.91

GC content: 45.52

Gene sequence:

>1740_bases
ATGTCCGAACGCACCTTAATTTGGAAAAACAAGCACATCAGATCGCAAGTTGATGTTGTAAGTTCAAGGCTGCAGCCAAC
GCTCCTTTTACGAAATGCATCTGTACTGAACCCGTATGTAAAGCAATGGATTCCAGCAAACGTATGGATTCATCATGACA
GAATCGTTTATGTCGGCCGTGACTTGCCGAAGACGGCTGTTAAAACTACAATAGATTGTGAAGGAAAATACATTGTACCC
GGGTATATTGAGCCGCATGTACATCCTTTTCAAATTTATAATCCCCAAACTTTGGCCGAATATGTGTCACAGTTTGGAAC
GACCACATTCGTAAATGACAACTTGTTTCTGCTTTTACATTGCGGAAAAAAGAAAGCGTTTTCTATACTGGAGGAACTGA
AAAAACAGCCTGTCCACTACTATTGGTGGTCAAGGTATGACTTGCAGACCGAAGTGTTGAATGAAGATCAAATCTTATCG
ATCGATTACCGAAAACATTGGGGAGAACACCCGGATGTCATCCAGGGAGGAGAAATGACAGGCTGGCCGCGCCTTTTGGA
CGGCGATGATCTGATCCTTCATTGCATGCAGTGCACGAAAAGAAGGAGAAAGCGGATCGAGGGCCATTTTCCGGGGGCAT
CGGAAAAAACGCTGACGAAGATGAAGCTTTTCGGCGCTGACGCCGATCATGAAGCCATGACTGGAAAGGAAGTGCTGAAG
CGGCTTGAACTTGGTTACCACGTCGGCTTGAGGCAGTCTTCCATCCGCCCTGATTTGCGAAAAATTTTGCGCGAGCTGCA
CGAAGAAGGCTTTCACCATTATGACCATATGTTTTATACAACGGACGGCGCAACGCCGAACTTTTATAAAGAAGGCATGA
CAAACAAGCTGATTGAAATCGCCATCGAAGAGGGCGTGCCGCTGATCGACGCCTATAATATGGCTTCGTTTAATATCGCG
AAGTATTACCATATGGAGGACATCCTTGGGGTGGTTGCACCGGGCAGATACGCGACGCTCAACATTTTGAATAGCCCTGA
TGAACCGAATCCGGAGACGGTTTTGGCAAAAGGTCGGCTGATCAAATCAGGCGGCATAAATATGAATGCGTTTTCAGTTC
CGGATTGGCAAAAAGGGGGTCTTGTCCCTCTGAACCTTTCATATGATCTAACGATGGATGATTTGCAGTTTTCCATGCCG
CTCGGCTTGAAAATGAGGAATTCCGTCATTATGGAGCCTTATACGATTGAGATTGACAACTCTGTGAACCAGCTTTCTTT
TGATCATGATGAAAGCTATCTCTCGCTGTTCGACAAATACGGAAAGTGGCGTGTCAATACGATGCTGAAAGGCTTTGCAA
CCCGCATCCAAGGTTTCGTCAGCTCCTATTCGACAACGGGAGACATTATCGCGATCGGCAAAAACAAGGAAGACATGCTT
TTGGCCTTCAAACGGATGAAAGAAATCGGAGGAGGTATCGTATTAGCGGAAAACGGAAAAATTCTGCACGAAATTCCTCT
TCATTTAAGCGGCGGCGCATCAATTGAGACGTATGAAAAGGTGCTTGAAAGGGAAAAAGCGTTAAAAGAGCTTCTGTTTG
AAAGAGGCTATACGTTCGACGACCCGATCTACACCCTGCTCTTTTTGCAAAGCACCCATCTGCCTTATATCAGGGTGACG
CCGAAAGGGATCTTTGATGTGATGAAAAAAACTGTACTCTTTCCATCGATAATGCGTTAA

Upstream 100 bases:

>100_bases
TAAATAAAGTGTTTTTTCAAAAAATTGTAACGGATTGGTAATGCGTGACGATAGTAAATGTGTTAACATAGGATCATTAC
ATGTAAAGGAGAGTATGTGA

Downstream 100 bases:

>100_bases
AATATAAAAGAGCGGGAGCTAATCTATGGTGAATCGATATGTAAGAGTACTGCTTTGTTTTGCTTCGCTTTTACTGCTTG
CATCGTGCCAGTCGCAGGAA

Product: YerA

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSERTLIWKNKHIRSQVDVVSSRLQPTLLLRNASVLNPYVKQWIPANVWIHHDRIVYVGRDLPKTAVKTTIDCEGKYIVP
GYIEPHVHPFQIYNPQTLAEYVSQFGTTTFVNDNLFLLLHCGKKKAFSILEELKKQPVHYYWWSRYDLQTEVLNEDQILS
IDYRKHWGEHPDVIQGGEMTGWPRLLDGDDLILHCMQCTKRRRKRIEGHFPGASEKTLTKMKLFGADADHEAMTGKEVLK
RLELGYHVGLRQSSIRPDLRKILRELHEEGFHHYDHMFYTTDGATPNFYKEGMTNKLIEIAIEEGVPLIDAYNMASFNIA
KYYHMEDILGVVAPGRYATLNILNSPDEPNPETVLAKGRLIKSGGINMNAFSVPDWQKGGLVPLNLSYDLTMDDLQFSMP
LGLKMRNSVIMEPYTIEIDNSVNQLSFDHDESYLSLFDKYGKWRVNTMLKGFATRIQGFVSSYSTTGDIIAIGKNKEDML
LAFKRMKEIGGGIVLAENGKILHEIPLHLSGGASIETYEKVLEREKALKELLFERGYTFDDPIYTLLFLQSTHLPYIRVT
PKGIFDVMKKTVLFPSIMR

Sequences:

>Translated_579_residues
MSERTLIWKNKHIRSQVDVVSSRLQPTLLLRNASVLNPYVKQWIPANVWIHHDRIVYVGRDLPKTAVKTTIDCEGKYIVP
GYIEPHVHPFQIYNPQTLAEYVSQFGTTTFVNDNLFLLLHCGKKKAFSILEELKKQPVHYYWWSRYDLQTEVLNEDQILS
IDYRKHWGEHPDVIQGGEMTGWPRLLDGDDLILHCMQCTKRRRKRIEGHFPGASEKTLTKMKLFGADADHEAMTGKEVLK
RLELGYHVGLRQSSIRPDLRKILRELHEEGFHHYDHMFYTTDGATPNFYKEGMTNKLIEIAIEEGVPLIDAYNMASFNIA
KYYHMEDILGVVAPGRYATLNILNSPDEPNPETVLAKGRLIKSGGINMNAFSVPDWQKGGLVPLNLSYDLTMDDLQFSMP
LGLKMRNSVIMEPYTIEIDNSVNQLSFDHDESYLSLFDKYGKWRVNTMLKGFATRIQGFVSSYSTTGDIIAIGKNKEDML
LAFKRMKEIGGGIVLAENGKILHEIPLHLSGGASIETYEKVLEREKALKELLFERGYTFDDPIYTLLFLQSTHLPYIRVT
PKGIFDVMKKTVLFPSIMR
>Mature_578_residues
SERTLIWKNKHIRSQVDVVSSRLQPTLLLRNASVLNPYVKQWIPANVWIHHDRIVYVGRDLPKTAVKTTIDCEGKYIVPG
YIEPHVHPFQIYNPQTLAEYVSQFGTTTFVNDNLFLLLHCGKKKAFSILEELKKQPVHYYWWSRYDLQTEVLNEDQILSI
DYRKHWGEHPDVIQGGEMTGWPRLLDGDDLILHCMQCTKRRRKRIEGHFPGASEKTLTKMKLFGADADHEAMTGKEVLKR
LELGYHVGLRQSSIRPDLRKILRELHEEGFHHYDHMFYTTDGATPNFYKEGMTNKLIEIAIEEGVPLIDAYNMASFNIAK
YYHMEDILGVVAPGRYATLNILNSPDEPNPETVLAKGRLIKSGGINMNAFSVPDWQKGGLVPLNLSYDLTMDDLQFSMPL
GLKMRNSVIMEPYTIEIDNSVNQLSFDHDESYLSLFDKYGKWRVNTMLKGFATRIQGFVSSYSTTGDIIAIGKNKEDMLL
AFKRMKEIGGGIVLAENGKILHEIPLHLSGGASIETYEKVLEREKALKELLFERGYTFDDPIYTLLFLQSTHLPYIRVTP
KGIFDVMKKTVLFPSIMR

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=558, Percent_Identity=25.2688172043011, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 66524; Mature: 66392

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERTLIWKNKHIRSQVDVVSSRLQPTLLLRNASVLNPYVKQWIPANVWIHHDRIVYVGR
CCCCEEEECCCHHHHHHHHHHHCCCCEEEECCCHHHCHHHHHCCCCCEEEECCEEEEECC
DLPKTAVKTTIDCEGKYIVPGYIEPHVHPFQIYNPQTLAEYVSQFGTTTFVNDNLFLLLH
CCCHHHHCEEEECCCCEEECCCCCCCCCEEEEECHHHHHHHHHHCCCEEEECCCEEEEEE
CGKKKAFSILEELKKQPVHYYWWSRYDLQTEVLNEDQILSIDYRKHWGEHPDVIQGGEMT
CCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCC
GWPRLLDGDDLILHCMQCTKRRRKRIEGHFPGASEKTLTKMKLFGADADHEAMTGKEVLK
CCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEECCCCCCHHCCHHHHHH
RLELGYHVGLRQSSIRPDLRKILRELHEEGFHHYDHMFYTTDGATPNFYKEGMTNKLIEI
HHHHCCEECCCCCCCCHHHHHHHHHHHHCCCHHHCCEEEEECCCCCHHHHCCCHHHHHHH
AIEEGVPLIDAYNMASFNIAKYYHMEDILGVVAPGRYATLNILNSPDEPNPETVLAKGRL
HHHCCCCEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEECCEE
IKSGGINMNAFSVPDWQKGGLVPLNLSYDLTMDDLQFSMPLGLKMRNSVIMEPYTIEIDN
EECCCCCCEEECCCCCCCCCEEEEEEEECCCHHCEEECCCCCEEECCCEEECCEEEEECC
SVNQLSFDHDESYLSLFDKYGKWRVNTMLKGFATRIQGFVSSYSTTGDIIAIGKNKEDML
CCCCCCCCCCHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHH
LAFKRMKEIGGGIVLAENGKILHEIPLHLSGGASIETYEKVLEREKALKELLFERGYTFD
HHHHHHHHHCCCEEEECCCCEEEEECEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
DPIYTLLFLQSTHLPYIRVTPKGIFDVMKKTVLFPSIMR
CHHHEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SERTLIWKNKHIRSQVDVVSSRLQPTLLLRNASVLNPYVKQWIPANVWIHHDRIVYVGR
CCCEEEECCCHHHHHHHHHHHCCCCEEEECCCHHHCHHHHHCCCCCEEEECCEEEEECC
DLPKTAVKTTIDCEGKYIVPGYIEPHVHPFQIYNPQTLAEYVSQFGTTTFVNDNLFLLLH
CCCHHHHCEEEECCCCEEECCCCCCCCCEEEEECHHHHHHHHHHCCCEEEECCCEEEEEE
CGKKKAFSILEELKKQPVHYYWWSRYDLQTEVLNEDQILSIDYRKHWGEHPDVIQGGEMT
CCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCC
GWPRLLDGDDLILHCMQCTKRRRKRIEGHFPGASEKTLTKMKLFGADADHEAMTGKEVLK
CCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEECCCCCCHHCCHHHHHH
RLELGYHVGLRQSSIRPDLRKILRELHEEGFHHYDHMFYTTDGATPNFYKEGMTNKLIEI
HHHHCCEECCCCCCCCHHHHHHHHHHHHCCCHHHCCEEEEECCCCCHHHHCCCHHHHHHH
AIEEGVPLIDAYNMASFNIAKYYHMEDILGVVAPGRYATLNILNSPDEPNPETVLAKGRL
HHHCCCCEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEECCEE
IKSGGINMNAFSVPDWQKGGLVPLNLSYDLTMDDLQFSMPLGLKMRNSVIMEPYTIEIDN
EECCCCCCEEECCCCCCCCCEEEEEEEECCCHHCEEECCCCCEEECCCEEECCEEEEECC
SVNQLSFDHDESYLSLFDKYGKWRVNTMLKGFATRIQGFVSSYSTTGDIIAIGKNKEDML
CCCCCCCCCCHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHH
LAFKRMKEIGGGIVLAENGKILHEIPLHLSGGASIETYEKVLEREKALKELLFERGYTFD
HHHHHHHHHCCCEEEECCCCEEEEECEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
DPIYTLLFLQSTHLPYIRVTPKGIFDVMKKTVLFPSIMR
CHHHEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9701819; 8969499; 9384377 [H]