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The map label for this gene is moaC

Identifier: 52784423

GI number: 52784423

Start: 623038

End: 623544

Strand: Direct

Name: moaC

Synonym: BLi00617

Alternate gene names: 52784423

Gene position: 623038-623544 (Clockwise)

Preceding gene: 52784421

Following gene: 52784424

Centisome position: 14.75

GC content: 47.93

Gene sequence:

>507_bases
ATGAATGAGTTTACACATTTTAATGAACAAGGCAGAGCCAAGATGGTTGATATAAGCGAAAAGGAAGCTTCAGTGCGCAC
AGCTGCGGCTGTTTCAAGCGTGTCCATGAATCGAGAAGTACATGAAAAAATCAAAAACCGCGAAATCGGAAAAGGCGATG
TGTTGGCGGTGGCGCAAGTGGCCGGAATCATGGCTGCAAAACAGACATCCGCCATCATCCCGATGTGTCATCCGATCGCT
CTGAAAGGAGTCGACATCGCCTTTTGCTGGGAGAAGAAAGAGCAGAAGAGCATCCTGCATATACAATCTAACGTCAAGAC
CAAAGGGAGCACAGGTGTGGAAATGGAAGCGTTAACGTCGGCCTCCGTATGTGCGCTGACCGTTTATGACATGTGCAAAG
CGGCGGATAAGGGAATGGTGATAGGACCGACCTTTCTTCTCGAAAAGACAGGCGGGAAAAACGGTGACTATAAAAGGGAA
AAAGCTGATGTAGACATGGAGGATTAG

Upstream 100 bases:

>100_bases
GCAGTCAGCAAACAATTAAGTGAAGTCTGGAAGATTTTAGCCAAAGAAAAAGACAGATTGAAAAAAATAGTGTATGATCA
TTATAAGGAGAGTTAAGAAC

Downstream 100 bases:

>100_bases
TTTATGAACATGGATCATTCAAAAATTCCGCAAGCGACAGCGAAACGGCTGCCATTATATTATCGTTTTTTAAAAAACCT
TCATGCATCCGGGAAACAGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MNEFTHFNEQGRAKMVDISEKEASVRTAAAVSSVSMNREVHEKIKNREIGKGDVLAVAQVAGIMAAKQTSAIIPMCHPIA
LKGVDIAFCWEKKEQKSILHIQSNVKTKGSTGVEMEALTSASVCALTVYDMCKAADKGMVIGPTFLLEKTGGKNGDYKRE
KADVDMED

Sequences:

>Translated_168_residues
MNEFTHFNEQGRAKMVDISEKEASVRTAAAVSSVSMNREVHEKIKNREIGKGDVLAVAQVAGIMAAKQTSAIIPMCHPIA
LKGVDIAFCWEKKEQKSILHIQSNVKTKGSTGVEMEALTSASVCALTVYDMCKAADKGMVIGPTFLLEKTGGKNGDYKRE
KADVDMED
>Mature_168_residues
MNEFTHFNEQGRAKMVDISEKEASVRTAAAVSSVSMNREVHEKIKNREIGKGDVLAVAQVAGIMAAKQTSAIIPMCHPIA
LKGVDIAFCWEKKEQKSILHIQSNVKTKGSTGVEMEALTSASVCALTVYDMCKAADKGMVIGPTFLLEKTGGKNGDYKRE
KADVDMED

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=163, Percent_Identity=49.079754601227, Blast_Score=152, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI32566331, Length=150, Percent_Identity=45.3333333333333, Blast_Score=136, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=45, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28574492, Length=147, Percent_Identity=45.578231292517, Blast_Score=129, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_BACLD (Q65N05)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_077844.1
- RefSeq:   YP_090252.1
- HSSP:   P0A738
- ProteinModelPortal:   Q65N05
- SMR:   Q65N05
- STRING:   Q65N05
- EnsemblBacteria:   EBBACT00000058158
- EnsemblBacteria:   EBBACT00000059144
- GeneID:   3030740
- GeneID:   3098085
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00617
- KEGG:   bli:BL00846
- NMPDR:   fig|279010.5.peg.832
- eggNOG:   COG0315
- GeneTree:   EBGT00050000001026
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   BLIC279010-1:BLI00617-MONOMER
- BioCyc:   BLIC279010:BL00846-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 18236; Mature: 18236

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: ACT_SITE 130-130

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFTHFNEQGRAKMVDISEKEASVRTAAAVSSVSMNREVHEKIKNREIGKGDVLAVAQV
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHH
AGIMAAKQTSAIIPMCHPIALKGVDIAFCWEKKEQKSILHIQSNVKTKGSTGVEMEALTS
HHHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHCC
ASVCALTVYDMCKAADKGMVIGPTFLLEKTGGKNGDYKREKADVDMED
CHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNEFTHFNEQGRAKMVDISEKEASVRTAAAVSSVSMNREVHEKIKNREIGKGDVLAVAQV
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHH
AGIMAAKQTSAIIPMCHPIALKGVDIAFCWEKKEQKSILHIQSNVKTKGSTGVEMEALTS
HHHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHCC
ASVCALTVYDMCKAADKGMVIGPTFLLEKTGGKNGDYKREKADVDMED
CHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA