Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 52784421

GI number: 52784421

Start: 619701

End: 620726

Strand: Direct

Name: gcp

Synonym: BLi00615

Alternate gene names: 52784421

Gene position: 619701-620726 (Clockwise)

Preceding gene: 52784420

Following gene: 52784423

Centisome position: 14.68

GC content: 51.46

Gene sequence:

>1026_bases
ATGAATCATAAAAAAGATCTGTATGTATTAGGAATCGAAACAAGCTGTGATGAGACTGCCGCTGCGATTGTCAAAAACGG
GACGGACATCATCTCAAATGTCGTAGCGTCGCAAATCGAGAGTCATAAACGGTTTGGGGGCGTCGTTCCCGAGATCGCAT
CAAGGCATCACGTGGAACAGATCACGATCGTGCTTGAGGAAGCCTTTGCACAAGCGGACATGACGTTTGATGACATTGAT
GCCATTGCAGTAACGGAAGGACCGGGGCTTGTAGGCGCTCTATTGATCGGCGTGAATGCTGCGAAAGCGCTCAGTTTTGC
CCGGGGCATACCGCTCGTAGGCGTGCATCATATTGCCGGTCACATCTATGCCAACAGGCTTGTTCAGGACATTCAATTTC
CGGCGATTGCCCTTGTCGTCTCAGGCGGCCACACCGAACTCGTATATATGAAAGAGCACGGCTCATTTGAAGTAATCGGA
GAGACGCTCGACGATGCTGCAGGCGAAGCCTATGACAAAGTGGCGAGAACGATGGGGCTTCCTTATCCGGGTGGACCTCA
CATTGACAAACTTGCGCAAAAAGGCGAGGCAAATGTGCCGCTGCCGCGCGCATGGCTTGAAGAAGGGTCTTATCATTTCA
GCTTCAGCGGATTGAAGTCTGCAGTCATCAACACGCTTCACAACGCTTCACAAAAAGGCGAAACGATAGCTCCGGAAGAT
TTGTCAGCCAGCTTTCAGGAAAGCGTCATAGATGTCCTCGTGACAAAAACGGAACGCGCTGCGGAAGCTTATGGCGTCAA
ACAGGTGCTGCTTGCCGGAGGAGTTGCTGCAAACAAAGGGCTGAGAGCCGCGCTCGAAAAAACGTTCAGCAGCCGTCCGG
AGATCGAGCTTTTGATCCCGCCGCTCTCGCTGTGTACGGACAATGCCGCCATGATTGCCGCCGCAGGTACGGTTGCTTTT
GAAAAAGGAATCAGAGGAAAATATGATATGAATGGTCAGCCTGGCTTAGATCTGACGTCTTATTGA

Upstream 100 bases:

>100_bases
CAGAGCTTATACAAAAAGCTCGGCTTTGAGCCGGGAGGAATTCGCAAAAATTATTATACCGATAATGGGGAAGATGCATT
ATTAATGTGGGTGAGACTAA

Downstream 100 bases:

>100_bases
AACCTCACGCTTTGTGAGGTTTTTTTACCCGGAAAAAGTTATTAACAAGTTATCAACACATATCCACAGTCTTGTGTATA
ATGTTAAAAACCTTAATTTA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNHKKDLYVLGIETSCDETAAAIVKNGTDIISNVVASQIESHKRFGGVVPEIASRHHVEQITIVLEEAFAQADMTFDDID
AIAVTEGPGLVGALLIGVNAAKALSFARGIPLVGVHHIAGHIYANRLVQDIQFPAIALVVSGGHTELVYMKEHGSFEVIG
ETLDDAAGEAYDKVARTMGLPYPGGPHIDKLAQKGEANVPLPRAWLEEGSYHFSFSGLKSAVINTLHNASQKGETIAPED
LSASFQESVIDVLVTKTERAAEAYGVKQVLLAGGVAANKGLRAALEKTFSSRPEIELLIPPLSLCTDNAAMIAAAGTVAF
EKGIRGKYDMNGQPGLDLTSY

Sequences:

>Translated_341_residues
MNHKKDLYVLGIETSCDETAAAIVKNGTDIISNVVASQIESHKRFGGVVPEIASRHHVEQITIVLEEAFAQADMTFDDID
AIAVTEGPGLVGALLIGVNAAKALSFARGIPLVGVHHIAGHIYANRLVQDIQFPAIALVVSGGHTELVYMKEHGSFEVIG
ETLDDAAGEAYDKVARTMGLPYPGGPHIDKLAQKGEANVPLPRAWLEEGSYHFSFSGLKSAVINTLHNASQKGETIAPED
LSASFQESVIDVLVTKTERAAEAYGVKQVLLAGGVAANKGLRAALEKTFSSRPEIELLIPPLSLCTDNAAMIAAAGTVAF
EKGIRGKYDMNGQPGLDLTSY
>Mature_341_residues
MNHKKDLYVLGIETSCDETAAAIVKNGTDIISNVVASQIESHKRFGGVVPEIASRHHVEQITIVLEEAFAQADMTFDDID
AIAVTEGPGLVGALLIGVNAAKALSFARGIPLVGVHHIAGHIYANRLVQDIQFPAIALVVSGGHTELVYMKEHGSFEVIG
ETLDDAAGEAYDKVARTMGLPYPGGPHIDKLAQKGEANVPLPRAWLEEGSYHFSFSGLKSAVINTLHNASQKGETIAPED
LSASFQESVIDVLVTKTERAAEAYGVKQVLLAGGVAANKGLRAALEKTFSSRPEIELLIPPLSLCTDNAAMIAAAGTVAF
EKGIRGKYDMNGQPGLDLTSY

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=350, Percent_Identity=32.5714285714286, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI8923380, Length=321, Percent_Identity=35.5140186915888, Blast_Score=158, Evalue=5e-39,
Organism=Escherichia coli, GI1789445, Length=330, Percent_Identity=43.030303030303, Blast_Score=274, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=33.1269349845201, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=33.1269349845201, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320099, Length=350, Percent_Identity=31.1428571428571, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322891, Length=353, Percent_Identity=30.8781869688385, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI20129063, Length=356, Percent_Identity=33.4269662921348, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=32.1321321321321, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_BACLD (Q65N07)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_077841.1
- RefSeq:   YP_090250.1
- ProteinModelPortal:   Q65N07
- SMR:   Q65N07
- STRING:   Q65N07
- MEROPS:   M22.001
- EnsemblBacteria:   EBBACT00000054199
- EnsemblBacteria:   EBBACT00000061519
- GeneID:   3030735
- GeneID:   3098308
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00615
- KEGG:   bli:BL00845
- NMPDR:   fig|279010.5.peg.830
- eggNOG:   COG0533
- GeneTree:   EBGT00050000002496
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   BLIC279010-1:BLI00615-MONOMER
- BioCyc:   BLIC279010:BL00845-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36166; Mature: 36166

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHKKDLYVLGIETSCDETAAAIVKNGTDIISNVVASQIESHKRFGGVVPEIASRHHVEQ
CCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ITIVLEEAFAQADMTFDDIDAIAVTEGPGLVGALLIGVNAAKALSFARGIPLVGVHHIAG
HHHHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
HIYANRLVQDIQFPAIALVVSGGHTELVYMKEHGSFEVIGETLDDAAGEAYDKVARTMGL
HHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCC
PYPGGPHIDKLAQKGEANVPLPRAWLEEGSYHFSFSGLKSAVINTLHNASQKGETIAPED
CCCCCCCHHHHHHCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHH
LSASFQESVIDVLVTKTERAAEAYGVKQVLLAGGVAANKGLRAALEKTFSSRPEIELLIP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHCCCCCEEEEEC
PLSLCTDNAAMIAAAGTVAFEKGIRGKYDMNGQPGLDLTSY
CHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNHKKDLYVLGIETSCDETAAAIVKNGTDIISNVVASQIESHKRFGGVVPEIASRHHVEQ
CCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ITIVLEEAFAQADMTFDDIDAIAVTEGPGLVGALLIGVNAAKALSFARGIPLVGVHHIAG
HHHHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
HIYANRLVQDIQFPAIALVVSGGHTELVYMKEHGSFEVIGETLDDAAGEAYDKVARTMGL
HHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCC
PYPGGPHIDKLAQKGEANVPLPRAWLEEGSYHFSFSGLKSAVINTLHNASQKGETIAPED
CCCCCCCHHHHHHCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCHH
LSASFQESVIDVLVTKTERAAEAYGVKQVLLAGGVAANKGLRAALEKTFSSRPEIELLIP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHCCCCCEEEEEC
PLSLCTDNAAMIAAAGTVAFEKGIRGKYDMNGQPGLDLTSY
CHHHHCCCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA