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The map label for this gene is tktA [C]

Identifier: 52784315

GI number: 52784315

Start: 501613

End: 502458

Strand: Direct

Name: tktA [C]

Synonym: BLi00495

Alternate gene names: 52784315

Gene position: 501613-502458 (Clockwise)

Preceding gene: 52784314

Following gene: 52784316

Centisome position: 11.88

GC content: 50.24

Gene sequence:

>846_bases
ATGATGTCAGTAAGGGAAATCGATATGGAGCGTTTTCGTGATCAAATCAGGCTGCTGACATTGAAACAGCTTCATCACCT
CGGCTTTGGACATTATGGTGGCAGCTTGTCAATCGCCGATGTGTTGGCCGTTTTGTATGGAAAGGTGATGAAAATAGATC
CTGCCAATCCGTCGTGGGAAGATCGGGACTTCTTTATCCTTTCAAAAGGGCACGGCGGCCCCGCCTTATATGCAGCGCTT
CATCTTTCCGGCTATTTTGAAGAAGATGTGCTCTATACGCTAAACCAAAACGGCACAGCTCTTCCGTCGCACCCTGACCG
AAATTTAACACCGGGAGTCGATATGACGACCGGGTCGCTGGGCCAGGGGATCTCGGCTGCAGCAGGAGTCGCGCTGTCGC
ACAAGCTTTCAGGACGCGCTAACCGCACCTTTGTCATTGTCGGCGACGGGGAGCTGAACGAAGGCCAATGCTGGGAAGCG
ATCCAATTTGCGGCGCACCATAAGCTCCGCAATCTTTATGTGTTTGTGGATGATAATAAACAACAGCTGGACGGCCCGAC
GAAAGAGATTATCGATCCGCTGGATTTTGTCAGCAAATTTAGAGCCTTCGGGTTTTATTCCGAAAGGGTAAACGGACACG
AACCGGAAGCGATTTATCGTGCGGTCAAAAGAGGCGAAGCCCAGCGGGAAAGGCCGGTTGCCGTCATCCTTGATACGGTG
AAGGGAAAGGGCATCCCTTATTTTGAAAAAATGGAGAACAGCCACCACATTAGAGCAAATGAAGAGCAAAACCGCATGAT
CGAAAGGATCATTTTGACGCTTGAAGAAAAGGAAGTGAGGGCATGA

Upstream 100 bases:

>100_bases
TTGGAATCGCAGCGGTAGTGGTTGGCGCAGTCTTGTTCGGCTTTAAACGCGGAAAGGCGGAAAAGCCAGATCAGAAAGTC
GAAGCATAAAGGAGTGGGCA

Downstream 100 bases:

>100_bases
ATGAGGCGGCAAATGTAGAGCTGGACGCTGTTGAAATGAGGCAGGCATACAGCTCAGCCGTTTATGAACTGGCTCAAGAA
AACACGGACATCGTGGCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MMSVREIDMERFRDQIRLLTLKQLHHLGFGHYGGSLSIADVLAVLYGKVMKIDPANPSWEDRDFFILSKGHGGPALYAAL
HLSGYFEEDVLYTLNQNGTALPSHPDRNLTPGVDMTTGSLGQGISAAAGVALSHKLSGRANRTFVIVGDGELNEGQCWEA
IQFAAHHKLRNLYVFVDDNKQQLDGPTKEIIDPLDFVSKFRAFGFYSERVNGHEPEAIYRAVKRGEAQRERPVAVILDTV
KGKGIPYFEKMENSHHIRANEEQNRMIERIILTLEEKEVRA

Sequences:

>Translated_281_residues
MMSVREIDMERFRDQIRLLTLKQLHHLGFGHYGGSLSIADVLAVLYGKVMKIDPANPSWEDRDFFILSKGHGGPALYAAL
HLSGYFEEDVLYTLNQNGTALPSHPDRNLTPGVDMTTGSLGQGISAAAGVALSHKLSGRANRTFVIVGDGELNEGQCWEA
IQFAAHHKLRNLYVFVDDNKQQLDGPTKEIIDPLDFVSKFRAFGFYSERVNGHEPEAIYRAVKRGEAQRERPVAVILDTV
KGKGIPYFEKMENSHHIRANEEQNRMIERIILTLEEKEVRA
>Mature_281_residues
MMSVREIDMERFRDQIRLLTLKQLHHLGFGHYGGSLSIADVLAVLYGKVMKIDPANPSWEDRDFFILSKGHGGPALYAAL
HLSGYFEEDVLYTLNQNGTALPSHPDRNLTPGVDMTTGSLGQGISAAAGVALSHKLSGRANRTFVIVGDGELNEGQCWEA
IQFAAHHKLRNLYVFVDDNKQQLDGPTKEIIDPLDFVSKFRAFGFYSERVNGHEPEAIYRAVKRGEAQRERPVAVILDTV
KGKGIPYFEKMENSHHIRANEEQNRMIERIILTLEEKEVRA

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=264, Percent_Identity=35.6060606060606, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI205277463, Length=247, Percent_Identity=35.2226720647773, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI4507521, Length=247, Percent_Identity=35.2226720647773, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI225637459, Length=266, Percent_Identity=26.3157894736842, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI225637463, Length=162, Percent_Identity=33.9506172839506, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI225637461, Length=162, Percent_Identity=33.9506172839506, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI48994911, Length=258, Percent_Identity=34.8837209302326, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788808, Length=262, Percent_Identity=33.587786259542, Blast_Score=144, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17539652, Length=249, Percent_Identity=35.3413654618474, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6325331, Length=256, Percent_Identity=36.71875, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319593, Length=242, Percent_Identity=33.8842975206612, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45551847, Length=250, Percent_Identity=35.2, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI45550715, Length=250, Percent_Identity=35.2, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666278, Length=276, Percent_Identity=32.2463768115942, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645119, Length=216, Percent_Identity=37.5, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 31586; Mature: 31586

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSVREIDMERFRDQIRLLTLKQLHHLGFGHYGGSLSIADVLAVLYGKVMKIDPANPSWE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCC
DRDFFILSKGHGGPALYAALHLSGYFEEDVLYTLNQNGTALPSHPDRNLTPGVDMTTGSL
CCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GQGISAAAGVALSHKLSGRANRTFVIVGDGELNEGQCWEAIQFAAHHKLRNLYVFVDDNK
CCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEECCH
QQLDGPTKEIIDPLDFVSKFRAFGFYSERVNGHEPEAIYRAVKRGEAQRERPVAVILDTV
HHCCCCHHHHCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCCHHCCCEEEEEECC
KGKGIPYFEKMENSHHIRANEEQNRMIERIILTLEEKEVRA
CCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSVREIDMERFRDQIRLLTLKQLHHLGFGHYGGSLSIADVLAVLYGKVMKIDPANPSWE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCC
DRDFFILSKGHGGPALYAALHLSGYFEEDVLYTLNQNGTALPSHPDRNLTPGVDMTTGSL
CCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GQGISAAAGVALSHKLSGRANRTFVIVGDGELNEGQCWEAIQFAAHHKLRNLYVFVDDNK
CCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEEECCH
QQLDGPTKEIIDPLDFVSKFRAFGFYSERVNGHEPEAIYRAVKRGEAQRERPVAVILDTV
HHCCCCHHHHCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHCCCHHCCCEEEEEECC
KGKGIPYFEKMENSHHIRANEEQNRMIERIILTLEEKEVRA
CCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]