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The map label for this gene is ycbA [H]

Identifier: 52784098

GI number: 52784098

Start: 248462

End: 249790

Strand: Direct

Name: ycbA [H]

Synonym: BLi00275

Alternate gene names: 52784098

Gene position: 248462-249790 (Clockwise)

Preceding gene: 52784093

Following gene: 52784099

Centisome position: 5.88

GC content: 46.95

Gene sequence:

>1329_bases
ATGATGGGTGGAAATCGGGGAAGCGTGATGACAAAAGCGGCCCGGCTTGTTAAAAAAGACGGCTATATCTTAATGGTGAT
GATGTTAACTGTGCCGCTGGCAGGAGAGCTGAAGTTTTATCCGCTGAACGAGACCTTCAGGGTCAGCTTCGGGGTTCCGA
CTTTCTTCTTTCTTTTGCTGCTGCTGCGGAATGTGCCGGCTGTGCTGTCCGGCTTTTTAACGGGGGCGGCAGTCGTCGGA
TTTCGTGTGCTGCTTGATGGATTTGGGCCGGGGCAGATCGATTGGCTGTCATCCTTTTACTACCATTATCCGACTTTTTT
CTTTTATTTCACATATGCGTTTCTATTCTACTTGGCAAAAGTGAAACGATTTCAATTTCGCCCGCTCTACATCGGGTTTC
TCGGCTTCGGAATCGAACTGATTGCCGATGGAGCCGAACTGGCCGTTCAATATATGATGTTCGAGTCTACCGTCACCCCG
GGAAAAATCCGCGACATGATGGCGATTGCTTTTTCCCACAGCTTTATTGTGCTGAGCTTTTTTAATGTCATGAAGCTGTA
TGAAACGCAATCGCGGGAAAAGCAGATCCGCGAACAAAATGAGCACATGCTGATGATCGTTTCAAACTTATATGAAGAAA
CCGTTCATTTGAAAAAGACGTTGAAGAATACTGAAGAGATTACAAACGAGTCCTATCAGCTGTACAGGCTCTTAAATAGA
CAGAGCGATAACAATTCCTCCGTCCGGCAGATCAGCCAGAAAGTGCTGCGCCTCGCCGGTGAAATCCATGAGGTCAAAAA
AGACAATCAGCGCATTTTCGCCGGACTTTCAAAATTAATTTCCAAAGAAAGCTTCAGAGACTACATGGCTGCAGAGGATC
TGGTCCGGCTTGTGACCGGCATAAATCGAAAGTATGCTGAATCGCTCGAAAAAGACATTGACTTTCATTATTCGATAGAC
GGAGAACATCCGAAATACCATGTGTATACCGTATTATCCGTAATTAATAATATTATGGCGAACGCGGTGGAAGCGATTCA
AAAGCAGGGCTCCATCAGACTCAGCCTCTATAGGCGCGGCGATGACATGCTGGAATGCCGCGTGGAAGATGACGGACCGG
GCATTCCCGAGAAAGTCGGAGATGTGGTGTTTGAGCCGGGATACACGTCAAAATATGATGAATTCGGAACTCCTTCAACC
GGAATCGGTCTGTCTTATGTGAAGGAAACTGTCGAGGAGCTTGGAGGGAGCATTCGATTCCGGAATGATGCAAGCGGTGT
TGTGTTTACGATCAGACTTCCGGTTCAACAATTGATTCAGAAAGGGTGA

Upstream 100 bases:

>100_bases
ATTGATTTAAAAATCAAATCGACTGTGGGTAAAATGGGAGTTGCGGATATTGTGCGATTAACGCCAAAATAAAGCAACAC
GTTTGTAATGGAGGATCAGC

Downstream 100 bases:

>100_bases
AGGCCTGTGCGTTTTTTTATTGCAGATGATGACCGTGCTGTGCGATCGATTTTAAAACAAATCATTGAAGACGAAGATTT
GGGTGAAGTGGCCGGAGAAG

Product: YcbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MMGGNRGSVMTKAARLVKKDGYILMVMMLTVPLAGELKFYPLNETFRVSFGVPTFFFLLLLLRNVPAVLSGFLTGAAVVG
FRVLLDGFGPGQIDWLSSFYYHYPTFFFYFTYAFLFYLAKVKRFQFRPLYIGFLGFGIELIADGAELAVQYMMFESTVTP
GKIRDMMAIAFSHSFIVLSFFNVMKLYETQSREKQIREQNEHMLMIVSNLYEETVHLKKTLKNTEEITNESYQLYRLLNR
QSDNNSSVRQISQKVLRLAGEIHEVKKDNQRIFAGLSKLISKESFRDYMAAEDLVRLVTGINRKYAESLEKDIDFHYSID
GEHPKYHVYTVLSVINNIMANAVEAIQKQGSIRLSLYRRGDDMLECRVEDDGPGIPEKVGDVVFEPGYTSKYDEFGTPST
GIGLSYVKETVEELGGSIRFRNDASGVVFTIRLPVQQLIQKG

Sequences:

>Translated_442_residues
MMGGNRGSVMTKAARLVKKDGYILMVMMLTVPLAGELKFYPLNETFRVSFGVPTFFFLLLLLRNVPAVLSGFLTGAAVVG
FRVLLDGFGPGQIDWLSSFYYHYPTFFFYFTYAFLFYLAKVKRFQFRPLYIGFLGFGIELIADGAELAVQYMMFESTVTP
GKIRDMMAIAFSHSFIVLSFFNVMKLYETQSREKQIREQNEHMLMIVSNLYEETVHLKKTLKNTEEITNESYQLYRLLNR
QSDNNSSVRQISQKVLRLAGEIHEVKKDNQRIFAGLSKLISKESFRDYMAAEDLVRLVTGINRKYAESLEKDIDFHYSID
GEHPKYHVYTVLSVINNIMANAVEAIQKQGSIRLSLYRRGDDMLECRVEDDGPGIPEKVGDVVFEPGYTSKYDEFGTPST
GIGLSYVKETVEELGGSIRFRNDASGVVFTIRLPVQQLIQKG
>Mature_442_residues
MMGGNRGSVMTKAARLVKKDGYILMVMMLTVPLAGELKFYPLNETFRVSFGVPTFFFLLLLLRNVPAVLSGFLTGAAVVG
FRVLLDGFGPGQIDWLSSFYYHYPTFFFYFTYAFLFYLAKVKRFQFRPLYIGFLGFGIELIADGAELAVQYMMFESTVTP
GKIRDMMAIAFSHSFIVLSFFNVMKLYETQSREKQIREQNEHMLMIVSNLYEETVHLKKTLKNTEEITNESYQLYRLLNR
QSDNNSSVRQISQKVLRLAGEIHEVKKDNQRIFAGLSKLISKESFRDYMAAEDLVRLVTGINRKYAESLEKDIDFHYSID
GEHPKYHVYTVLSVINNIMANAVEAIQKQGSIRLSLYRRGDDMLECRVEDDGPGIPEKVGDVVFEPGYTSKYDEFGTPST
GIGLSYVKETVEELGGSIRFRNDASGVVFTIRLPVQQLIQKG

Specific function: Member of the two-component regulatory system glnK/glnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates glnL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790567, Length=96, Percent_Identity=42.7083333333333, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50467; Mature: 50467

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGGNRGSVMTKAARLVKKDGYILMVMMLTVPLAGELKFYPLNETFRVSFGVPTFFFLLL
CCCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCCEEEEECCCEEEEEECCHHHHHHHH
LLRNVPAVLSGFLTGAAVVGFRVLLDGFGPGQIDWLSSFYYHYPTFFFYFTYAFLFYLAK
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRFQFRPLYIGFLGFGIELIADGAELAVQYMMFESTVTPGKIRDMMAIAFSHSFIVLSF
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
FNVMKLYETQSREKQIREQNEHMLMIVSNLYEETVHLKKTLKNTEEITNESYQLYRLLNR
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHC
QSDNNSSVRQISQKVLRLAGEIHEVKKDNQRIFAGLSKLISKESFRDYMAAEDLVRLVTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INRKYAESLEKDIDFHYSIDGEHPKYHVYTVLSVINNIMANAVEAIQKQGSIRLSLYRRG
CCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
DDMLECRVEDDGPGIPEKVGDVVFEPGYTSKYDEFGTPSTGIGLSYVKETVEELGGSIRF
CCEEEEEECCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
RNDASGVVFTIRLPVQQLIQKG
ECCCCCEEEEEECCHHHHHHCC
>Mature Secondary Structure
MMGGNRGSVMTKAARLVKKDGYILMVMMLTVPLAGELKFYPLNETFRVSFGVPTFFFLLL
CCCCCCCHHHHHHHHHHHCCCCEEEEHHHHCCCCCCEEEEECCCEEEEEECCHHHHHHHH
LLRNVPAVLSGFLTGAAVVGFRVLLDGFGPGQIDWLSSFYYHYPTFFFYFTYAFLFYLAK
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKRFQFRPLYIGFLGFGIELIADGAELAVQYMMFESTVTPGKIRDMMAIAFSHSFIVLSF
HHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
FNVMKLYETQSREKQIREQNEHMLMIVSNLYEETVHLKKTLKNTEEITNESYQLYRLLNR
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHC
QSDNNSSVRQISQKVLRLAGEIHEVKKDNQRIFAGLSKLISKESFRDYMAAEDLVRLVTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INRKYAESLEKDIDFHYSIDGEHPKYHVYTVLSVINNIMANAVEAIQKQGSIRLSLYRRG
CCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
DDMLECRVEDDGPGIPEKVGDVVFEPGYTSKYDEFGTPSTGIGLSYVKETVEELGGSIRF
CCEEEEEECCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
RNDASGVVFTIRLPVQQLIQKG
ECCCCCEEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8011666 [H]