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The map label for this gene is rocF [H]

Identifier: 52784026

GI number: 52784026

Start: 176978

End: 177892

Strand: Direct

Name: rocF [H]

Synonym: BLi00198

Alternate gene names: 52784026

Gene position: 176978-177892 (Clockwise)

Preceding gene: 52784017

Following gene: 52784027

Centisome position: 4.19

GC content: 51.04

Gene sequence:

>915_bases
ATGTTAAAACAGCAGATTTCAATGATCGGCGTGCCGATGGATCTTGGACAGCTGAGGCGGGGAGTCGATATGGGACCGAG
CGCGATTCGCTGTGCAGGTGTTAATGAACGGCTGGAATGTCTTTGTCAGGATATTGAAGACCTCGGCGATATGACGATCG
GGCAAAGAGAGGATGAGAAAGAAGGCGGGGAGCCGGCATCTGAAGAGCTAAGAAATTTGAAAGCGATTACAAAAGCGAGT
GTAAAACTTGCTGAGACTGTCGATAATATCGTAGCTTCTGGCGCTTTTCCGCTCGTGCTGGGCGGTGACCACAGCATTGC
GATCGGAACGCTTGCCGGCCTTGCGAAGCATTATCAAAACCTGGGTGTGATCTGGTATGACGCCCATGCCGATTTAAATA
CAAAAGAAACGTCTCCCTCAGGCAACATTCACGGCATGCCGCTCGCCATCAGCCTGGGAATCGGCCACGAAGGGCTGACC
GCCATCTATGGAAAAGAAGCTAAAATTAAAGCGGAGAACATCGTCATCATCGGTGCGAGGTCACTTGATGACGGGGAAAA
AGAATTGATTCGCGACAAAGGGATCAAAGTATATACGATGCATGAAATCGACCGCCTCGGCATGACAAGGGTGATGGAAG
AAACGATAGACTATTTGCGAGGCAGGACGGACGGTGTCCATCTGTCACTCGATTTGGACGCGCTTGATCCGAACGATGCA
CCGGGTGTCGGAACTCCGGTAGCAGGAGGCATCAGCTACAGGGAAAGCCATCTGGCTATGGAAATGCTTGAGGAATCGAA
GCTGATTACGTCCGCCGAGTTTGTCGAAGTAAACCCGATATTGGATGAGAAAAACAGGACGGCGGAAGCGGCTGTAGCCT
TAATGGGATCGCTGTTTGGCGAAAAGCTGCTTTAG

Upstream 100 bases:

>100_bases
CTTTTTATTTTGTCTTTTTTGTATAACTATTCAAAAAAATGTCTTGTTGAGTCAATTCCGAATCGGAAGGTACAATGAAG
GTCTGAAAGGGGGATATCAT

Downstream 100 bases:

>100_bases
GTGCAGTTGAAGAGCGGCTTCAGGCTGCTCTTTTTTATGATAGAAGTCTCAACTTCATAATATTTATGATGTATAATAAT
TTTAAGCTAATATTAAGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLKQQISMIGVPMDLGQLRRGVDMGPSAIRCAGVNERLECLCQDIEDLGDMTIGQREDEKEGGEPASEELRNLKAITKAS
VKLAETVDNIVASGAFPLVLGGDHSIAIGTLAGLAKHYQNLGVIWYDAHADLNTKETSPSGNIHGMPLAISLGIGHEGLT
AIYGKEAKIKAENIVIIGARSLDDGEKELIRDKGIKVYTMHEIDRLGMTRVMEETIDYLRGRTDGVHLSLDLDALDPNDA
PGVGTPVAGGISYRESHLAMEMLEESKLITSAEFVEVNPILDEKNRTAEAAVALMGSLFGEKLL

Sequences:

>Translated_304_residues
MLKQQISMIGVPMDLGQLRRGVDMGPSAIRCAGVNERLECLCQDIEDLGDMTIGQREDEKEGGEPASEELRNLKAITKAS
VKLAETVDNIVASGAFPLVLGGDHSIAIGTLAGLAKHYQNLGVIWYDAHADLNTKETSPSGNIHGMPLAISLGIGHEGLT
AIYGKEAKIKAENIVIIGARSLDDGEKELIRDKGIKVYTMHEIDRLGMTRVMEETIDYLRGRTDGVHLSLDLDALDPNDA
PGVGTPVAGGISYRESHLAMEMLEESKLITSAEFVEVNPILDEKNRTAEAAVALMGSLFGEKLL
>Mature_304_residues
MLKQQISMIGVPMDLGQLRRGVDMGPSAIRCAGVNERLECLCQDIEDLGDMTIGQREDEKEGGEPASEELRNLKAITKAS
VKLAETVDNIVASGAFPLVLGGDHSIAIGTLAGLAKHYQNLGVIWYDAHADLNTKETSPSGNIHGMPLAISLGIGHEGLT
AIYGKEAKIKAENIVIIGARSLDDGEKELIRDKGIKVYTMHEIDRLGMTRVMEETIDYLRGRTDGVHLSLDLDALDPNDA
PGVGTPVAGGISYRESHLAMEMLEESKLITSAEFVEVNPILDEKNRTAEAAVALMGSLFGEKLL

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=305, Percent_Identity=40, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4502215, Length=306, Percent_Identity=38.8888888888889, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI37537722, Length=304, Percent_Identity=28.2894736842105, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1789306, Length=294, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996843, Length=224, Percent_Identity=37.5, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6325146, Length=327, Percent_Identity=32.7217125382263, Blast_Score=164, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24638886, Length=311, Percent_Identity=33.4405144694534, Blast_Score=174, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32729; Mature: 32729

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQQISMIGVPMDLGQLRRGVDMGPSAIRCAGVNERLECLCQDIEDLGDMTIGQREDEK
CCCHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHH
EGGEPASEELRNLKAITKASVKLAETVDNIVASGAFPLVLGGDHSIAIGTLAGLAKHYQN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHC
LGVIWYDAHADLNTKETSPSGNIHGMPLAISLGIGHEGLTAIYGKEAKIKAENIVIIGAR
CCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCEEEECCEEEEEEC
SLDDGEKELIRDKGIKVYTMHEIDRLGMTRVMEETIDYLRGRTDGVHLSLDLDALDPNDA
CCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCC
PGVGTPVAGGISYRESHLAMEMLEESKLITSAEFVEVNPILDEKNRTAEAAVALMGSLFG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
EKLL
HHCC
>Mature Secondary Structure
MLKQQISMIGVPMDLGQLRRGVDMGPSAIRCAGVNERLECLCQDIEDLGDMTIGQREDEK
CCCHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHH
EGGEPASEELRNLKAITKASVKLAETVDNIVASGAFPLVLGGDHSIAIGTLAGLAKHYQN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHC
LGVIWYDAHADLNTKETSPSGNIHGMPLAISLGIGHEGLTAIYGKEAKIKAENIVIIGAR
CCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCCCEEEECCEEEEEEC
SLDDGEKELIRDKGIKVYTMHEIDRLGMTRVMEETIDYLRGRTDGVHLSLDLDALDPNDA
CCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCC
PGVGTPVAGGISYRESHLAMEMLEESKLITSAEFVEVNPILDEKNRTAEAAVALMGSLFG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
EKLL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]