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The map label for this gene is dgk [H]

Identifier: 52783873

GI number: 52783873

Start: 27215

End: 27838

Strand: Reverse

Name: dgk [H]

Synonym: BLi00024

Alternate gene names: 52783873

Gene position: 27838-27215 (Counterclockwise)

Preceding gene: 52783874

Following gene: 52783872

Centisome position: 0.66

GC content: 41.03

Gene sequence:

>624_bases
ATGAATACAGCCCCTTTCATTGCTGTCGAAGGCCCCATCGGCGCGGGAAAAACAACCTTGGCCAGCATGCTCTCCGAAAA
GCTCTCACTCTCTTTGGTCAAAGAAATCGTCGAAGAAAACCCTTTTCTTGATAAATTTTATGATGAAAAAGATGAATGGA
GCTTTCAGCTTGAGATGTTTTTCCTCTGCAATCGCTATAAGCAGCTTGAAGATACCGAGAAAAAGTATTTGCATCATCAC
ATGCCCGTTGTTTCGGACTATCATATTTATAAAAACCTCATTTTTGCCGAACGGACGCTGGAAGGCAAAAAACTTGAGAA
ATACAGAAAAATTTATCAGCTGCTTACAGAAGATCTGCCGAAACCAAACGTCATCATTTACATAAGAGCGAGTCTTCCAA
CTTTATTGGAACGGATCAAAAAACGCGGACGGCCGTTTGAACAAGAAATGGACAAGCAATACCTGGAACAGCTTATCAAT
GATTATGAGGCGGCCATTAAGCAATTTAAAGAATCCGATCCGCCAATACCCGTCATTGAAATTAACGGAGATCAGGAAGA
CTTCGTAATCTCAGAAGCCGTTTTCAATCGAATTGCCGATCAAGTAAAGGAGTATATAGAATGA

Upstream 100 bases:

>100_bases
CGTTCCCAAGTTAAAGGAACGTTTTTTTTCATGGCAGCGGATGATGATGTGATACAATATGTATGGTTCACAAATGAATT
TCTTTAGTAGGAGGACACCT

Downstream 100 bases:

>100_bases
GTGTATATGATATTCCGAAAGATGCTATCATTACTGTTGCAGGAACGGTAGGAGTGGGGAAATCCACATTGACAAAAGAG
CTTGCAAAAAGGCTCGGATT

Product: deoxyguanosine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNTAPFIAVEGPIGAGKTTLASMLSEKLSLSLVKEIVEENPFLDKFYDEKDEWSFQLEMFFLCNRYKQLEDTEKKYLHHH
MPVVSDYHIYKNLIFAERTLEGKKLEKYRKIYQLLTEDLPKPNVIIYIRASLPTLLERIKKRGRPFEQEMDKQYLEQLIN
DYEAAIKQFKESDPPIPVIEINGDQEDFVISEAVFNRIADQVKEYIE

Sequences:

>Translated_207_residues
MNTAPFIAVEGPIGAGKTTLASMLSEKLSLSLVKEIVEENPFLDKFYDEKDEWSFQLEMFFLCNRYKQLEDTEKKYLHHH
MPVVSDYHIYKNLIFAERTLEGKKLEKYRKIYQLLTEDLPKPNVIIYIRASLPTLLERIKKRGRPFEQEMDKQYLEQLIN
DYEAAIKQFKESDPPIPVIEINGDQEDFVISEAVFNRIADQVKEYIE
>Mature_207_residues
MNTAPFIAVEGPIGAGKTTLASMLSEKLSLSLVKEIVEENPFLDKFYDEKDEWSFQLEMFFLCNRYKQLEDTEKKYLHHH
MPVVSDYHIYKNLIFAERTLEGKKLEKYRKIYQLLTEDLPKPNVIIYIRASLPTLLERIKKRGRPFEQEMDKQYLEQLIN
DYEAAIKQFKESDPPIPVIEINGDQEDFVISEAVFNRIADQVKEYIE

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24431; Mature: 24431

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTAPFIAVEGPIGAGKTTLASMLSEKLSLSLVKEIVEENPFLDKFYDEKDEWSFQLEMF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHH
FLCNRYKQLEDTEKKYLHHHMPVVSDYHIYKNLIFAERTLEGKKLEKYRKIYQLLTEDLP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
KPNVIIYIRASLPTLLERIKKRGRPFEQEMDKQYLEQLINDYEAAIKQFKESDPPIPVIE
CCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
INGDQEDFVISEAVFNRIADQVKEYIE
ECCCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNTAPFIAVEGPIGAGKTTLASMLSEKLSLSLVKEIVEENPFLDKFYDEKDEWSFQLEMF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHH
FLCNRYKQLEDTEKKYLHHHMPVVSDYHIYKNLIFAERTLEGKKLEKYRKIYQLLTEDLP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
KPNVIIYIRASLPTLLERIKKRGRPFEQEMDKQYLEQLINDYEAAIKQFKESDPPIPVIE
CCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
INGDQEDFVISEAVFNRIADQVKEYIE
ECCCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]