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The map label for this gene is dck [H]

Identifier: 52783872

GI number: 52783872

Start: 26577

End: 27218

Strand: Reverse

Name: dck [H]

Synonym: BLi00023

Alternate gene names: 52783872

Gene position: 27218-26577 (Counterclockwise)

Preceding gene: 52783873

Following gene: 52783871

Centisome position: 0.64

GC content: 43.46

Gene sequence:

>642_bases
ATGAGTGTATATGATATTCCGAAAGATGCTATCATTACTGTTGCAGGAACGGTAGGAGTGGGGAAATCCACATTGACAAA
AGAGCTTGCAAAAAGGCTCGGATTTAAAACCTCTCTTGAAGAGGTCGTGAATAACCCTTATTTGGAGGCTTTTTACCAAG
ACTTTGAACGCTGGAGCTTTCACCTGCAGATTTTCTTCTTGGCAGAGCGCTTCAAAGAACAAAAATACATTTACGAATCG
GGCGGCGGATTTGTTCAGGACCGTTCAATTTATGAAGATACAGGCATTTTCGCCAAAATGCACGCCGATAAAGGCACAAT
GTCAAAAGTCGACTATAAGACGTATACGAGCCTGTTTGAAGCGATGGTCATGACGCCTTACTTCCCCCGCCCCGACGTTT
TAGTCTATTTAGAGGGCGATTTGGAAACGATTCTCGACCGCATCCAAAAACGCGGACGGGAAATGGAACTGTTAACCGAC
AGATCGTATTGGGAAGAAATGTACACTAGGTATGAAAACTGGATCAGCGGATTTAACGCCTGTCCGGTTGTCAGAGTCAA
TATTGATGAATACGACCTGTTCAACAACTCAGCCTCTCTCGATCCAATCATTGAAAAAATCAGTGAAGCCATTCAAAGAT
AA

Upstream 100 bases:

>100_bases
CGCCAATACCCGTCATTGAAATTAACGGAGATCAGGAAGACTTCGTAATCTCAGAAGCCGTTTTCAATCGAATTGCCGAT
CAAGTAAAGGAGTATATAGA

Downstream 100 bases:

>100_bases
ACAAGCAAAAAGAGCGGATTCCCTTGAAGAGCCGCTCTTTTTGCTGCATATAAAAAAACCGCTGCCCTATCCAGGCAGCG
GCAACACAATCTCCAATTTA

Product: deoxyadenosine/deoxycytidine kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSVYDIPKDAIITVAGTVGVGKSTLTKELAKRLGFKTSLEEVVNNPYLEAFYQDFERWSFHLQIFFLAERFKEQKYIYES
GGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFEAMVMTPYFPRPDVLVYLEGDLETILDRIQKRGREMELLTD
RSYWEEMYTRYENWISGFNACPVVRVNIDEYDLFNNSASLDPIIEKISEAIQR

Sequences:

>Translated_213_residues
MSVYDIPKDAIITVAGTVGVGKSTLTKELAKRLGFKTSLEEVVNNPYLEAFYQDFERWSFHLQIFFLAERFKEQKYIYES
GGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFEAMVMTPYFPRPDVLVYLEGDLETILDRIQKRGREMELLTD
RSYWEEMYTRYENWISGFNACPVVRVNIDEYDLFNNSASLDPIIEKISEAIQR
>Mature_212_residues
SVYDIPKDAIITVAGTVGVGKSTLTKELAKRLGFKTSLEEVVNNPYLEAFYQDFERWSFHLQIFFLAERFKEQKYIYESG
GGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFEAMVMTPYFPRPDVLVYLEGDLETILDRIQKRGREMELLTDR
SYWEEMYTRYENWISGFNACPVVRVNIDEYDLFNNSASLDPIIEKISEAIQR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 24861; Mature: 24729

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYDIPKDAIITVAGTVGVGKSTLTKELAKRLGFKTSLEEVVNNPYLEAFYQDFERWSF
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
HLQIFFLAERFKEQKYIYESGGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFE
HHHHHHHHHHHHHHHHEEECCCCEEECCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
AMVMTPYFPRPDVLVYLEGDLETILDRIQKRGREMELLTDRSYWEEMYTRYENWISGFNA
HHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
CPVVRVNIDEYDLFNNSASLDPIIEKISEAIQR
CCEEEEECCHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SVYDIPKDAIITVAGTVGVGKSTLTKELAKRLGFKTSLEEVVNNPYLEAFYQDFERWSF
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
HLQIFFLAERFKEQKYIYESGGGFVQDRSIYEDTGIFAKMHADKGTMSKVDYKTYTSLFE
HHHHHHHHHHHHHHHHEEECCCCEEECCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHH
AMVMTPYFPRPDVLVYLEGDLETILDRIQKRGREMELLTDRSYWEEMYTRYENWISGFNA
HHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCC
CPVVRVNIDEYDLFNNSASLDPIIEKISEAIQR
CCEEEEECCHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]