Click here to switch to the map view.

The map label for this gene is napA [H]

Identifier: 52144612

GI number: 52144612

Start: 707188

End: 709017

Strand: Reverse

Name: napA [H]

Synonym: BCZK0610

Alternate gene names: 52144612

Gene position: 709017-707188 (Counterclockwise)

Preceding gene: 52144611

Following gene: 52144614

Centisome position: 13.38

GC content: 35.3

Gene sequence:

>1830_bases
ATGGAACATCACACTTCTGTTCTATCACTTATGGTTGTCGTTGCAATCGCGTTTTTCGTTCCCCTTTTGTTACAACGCTT
TAAATTAAAAGCACTTCCTGTCGTTGTTGCAGAAATCATCGCAGGAATCTTTGTAGGTAAAAGTGGGTTTAATATTATTG
AGCCAGATATGTGGCTTCAAGTCTTATCGACACTAGGATTTATCTTTCTTATGTTTTTAAGCGGTTTAGAAATTGATTTT
TCTATCTTTAAACAAAAAGGGAAAAAGAATACGACAAACGAACCAAACACATTCCAAGCAGCAAGTGTTATCTTCTTATT
TATTTTCATCTTATCTTATGCCCTATCATTACTATTCGTATGGTTAGGATTTGTAGATAATGCAATGTTTATGACTTTAA
TTATTTCAACAATCTCTTTAGGTGTTGTCGTACCAACATTAAAAGAGAATAACCTAGGAAAAACAGCAATTGGACAAATC
ATTTTATTGGTCGCTGTTATTGCAGATTTAGTTACAATGATTTTACTTGCTGTATTCGTCGGATTAAATTCCGAAAGCGG
CCAAAGCATGTGGCTCCTTCTTCTTCTATTCGGCGCTGGTATTGTTATTTACTTCGTTGCAAAACGTTTTAAAAACATTC
CATACTTAGATAGCTTAAAAGCTGGTAGTGTACAAATTGATACAAGAGCTGTTTTTGCACTCATCTTAATATTAGTTGGG
TTATCTGAATCCGTTGGAGCCGAAAATATTTTAGGTGCCTTCTTAGCAGGTGTACTCGTATCATTATTATCACCAAATGA
AGATATGGTTGAAAAACTGGATTCTATCGGATACGGTTTCTTCATTCCTATTTTCTTCGTAATGGTTGGTGTAAATTTAG
AGGTCTGGTCTATTTTCAAAGAACCTTCTAGCATGCTCATGATCCCAATTTTAATTGTAGGACTCTTTATTTCAAAACTG
ATACCATCACTCGTCTTACGAAAATGGTATCCACGTAATATCGTACTAGGAAGTGCCATCTTATTAACATCGACACTTTC
TTTAGTTATTGCAGCTGCACAAATTGGTGAAAAACTAGGAATCATTAGTCCAAGTTTATCTGCCTCCCTTATTTTAAGCG
CAGTTATTACTTGTATTTTCGCACCTATATTATTTAAAAAGATGTTCCCAAAAGTGGAAACACCAAAACCAAAAGTTTCA
ATAATTGGTGCGAGCAGAATTACCCTTCCGTTATCACTTGATTTAAAACGAGAAGATTATGATGTAACACTATATATGAT
GCGTCAAAATAAAATAAATGATGAGGAAGCGAAATCACACGACTTCCCTATTGTGAAATTAGATGACATCACAATTGCAT
CATTAACTGAACAAACAGCATTTCATGCAGACCGTGTTGTTGTTGCAACAAGTGATGATGAACAAAACTTACTATTAGCA
GAACATGCAAAAGAACTAGGTGTTGAACATGTTATTGCAAGTGTAGAAGATCCGCTTCTACAAGAAAAAGCAACACAAGA
ACATATCGCCGTATTCTCAACCATTAACTCTACACGTATTCTATTACGTGCATTAATTGATAAACCGAGTCTCGTTCGCT
TAATTACAACAGCAAACGAAACAGTCCGTGAAGTTGAACTACGAAGCAATAAATATAACGGCGTTGCACTTCGTCGCCTT
CCGTTTTTAGGCGATGTACTAGTCATTCAAATTTATCGTGGGAATAAAGCATTAATCCCGCATGGTGATACAAGACTACA
ACACGGTGATACATTACTTGTAACAGGATCGAAAGAACATATCGATACACTAAAAAGCATATTAGAATAG

Upstream 100 bases:

>100_bases
AAGAAAACTCTTTCTTTATGAAATCGAATCCATATGCGTTGCTTTTCTACCTATTATATGGCTAAATAAGTACTATATTT
ATTTGAAGGGAGAGAACGCA

Downstream 100 bases:

>100_bases
AAAAATGCCCCTTACATAATTAAGGGGCATTTTTTTCCATTTCATATGGTAAAATGTTACTATCACATATTATGAGGATG
GATTACATTATGTCTATTAT

Product: Na+/H+ antiporter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQVLSTLGFIFLMFLSGLEIDF
SIFKQKGKKNTTNEPNTFQAASVIFLFIFILSYALSLLFVWLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQI
ILLVAVIADLVTMILLAVFVGLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDSLKAGSVQIDTRAVFALILILVG
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFKEPSSMLMIPILIVGLFISKL
IPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLGIISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVS
IIGASRITLPLSLDLKREDYDVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANETVREVELRSNKYNGVALRRL
PFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEHIDTLKSILE

Sequences:

>Translated_609_residues
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQVLSTLGFIFLMFLSGLEIDF
SIFKQKGKKNTTNEPNTFQAASVIFLFIFILSYALSLLFVWLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQI
ILLVAVIADLVTMILLAVFVGLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDSLKAGSVQIDTRAVFALILILVG
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFKEPSSMLMIPILIVGLFISKL
IPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLGIISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVS
IIGASRITLPLSLDLKREDYDVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANETVREVELRSNKYNGVALRRL
PFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEHIDTLKSILE
>Mature_609_residues
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQVLSTLGFIFLMFLSGLEIDF
SIFKQKGKKNTTNEPNTFQAASVIFLFIFILSYALSLLFVWLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQI
ILLVAVIADLVTMILLAVFVGLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDSLKAGSVQIDTRAVFALILILVG
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFKEPSSMLMIPILIVGLFISKL
IPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLGIISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVS
IIGASRITLPLSLDLKREDYDVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANETVREVELRSNKYNGVALRRL
PFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEHIDTLKSILE

Specific function: Probable Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=519, Percent_Identity=22.1579961464355, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322367, Length=402, Percent_Identity=23.6318407960199, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 67044; Mature: 67044

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VLSTLGFIFLMFLSGLEIDFSIFKQKGKKNTTNEPNTFQAASVIFLFIFILSYALSLLFV
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQIILLVAVIADLVTMILLAVFV
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDSLKAGSVQIDTRAVFALILILVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHC
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
EPSSMLMIPILIVGLFISKLIPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVSIIGASRITLPLSLDLKREDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEEECCCCCC
DVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
CEEEEEEECCCCCCHHHHCCCCCEEEECCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHH
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHH
TVREVELRSNKYNGVALRRLPFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEH
HHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEEECCHHH
IDTLKSILE
HHHHHHHHC
>Mature Secondary Structure
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VLSTLGFIFLMFLSGLEIDFSIFKQKGKKNTTNEPNTFQAASVIFLFIFILSYALSLLFV
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQIILLVAVIADLVTMILLAVFV
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDSLKAGSVQIDTRAVFALILILVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHC
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
EPSSMLMIPILIVGLFISKLIPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVSIIGASRITLPLSLDLKREDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEEECCCCCC
DVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
CEEEEEEECCCCCCHHHHCCCCCEEEECCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHH
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHH
TVREVELRSNKYNGVALRRLPFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEH
HHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEEECCHHH
IDTLKSILE
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]