Click here to switch to the map view.

The map label for this gene is uvrD [H]

Identifier: 52144276

GI number: 52144276

Start: 1060446

End: 1062779

Strand: Reverse

Name: uvrD [H]

Synonym: BCZK0951

Alternate gene names: 52144276

Gene position: 1062779-1060446 (Counterclockwise)

Preceding gene: 52144275

Following gene: 52144277

Centisome position: 20.05

GC content: 39.59

Gene sequence:

>2334_bases
ATGAACAAAAAACTTGATCAAGAGCAAAAACGATTGGATACCGTAATCGAAACGATTACGCAGCAAATTGATAAGCTGGA
AAACGAAACTGGCAGACGCCGAGCAGAAGTAATCAATATTCGTAAACATTTCTGGGATGACGTGAAAGTGAATACTGATA
CTTTTGATGATTATCTTGAAACAGTTATCAACTTAAGGCAACAAGCTCAGTCACTAGCTGTCACACAAATTACTCATAAG
CACACCTTTAATCGACTTGCCGCACTAAAACGCATGCATAAATCACCTTATTTTGGACGAATTGATTTCAAAGAAGAAGG
AGAATCTGCTGCGGAGAAAATTTATATTGGCGTAGCTACACTTACTGATGCGAGCGGAGAAAACTTTCTTATATATGACT
GGCGCGCACCCATTTCGAGTGTCTACTACGATTATCCACCAGGACCGGCTGAATACAGTACACCAGGTGGCGTAATTCAC
GGTAATGTGGAGAAAAAATTACAATACATTATTCAAAATGGCGAGATTGATTCTATGTTCGATACGAGCCTTACAATTGG
CGATGAAATCTTGCAACAAGCGCTCGGAAAAGGCACAAACAAACATATGCAAAGTATCGTTGCTACGATTCAGCGCGAGC
AAAATGAAATTATTCGTCACGATGAAGGCCGACTCCTTATCGTACAAGGAGCTGCTGGTAGCGGTAAAACGTCAGCCGCC
CTGCAACGAATCGCCTACTTACTATATAAATATCGCGAATGGTTAAAAGCGGATCAAATTATTCTCTTCTCCCCTAACTC
TATGTTCAACAGCTACGTTTCTAACGTACTACCTGAACTTGGTGAAGAGAATATGCAGCAAGTTACATTCCAAGAATATT
TAAACCATAGACTAAGTAAGTCATTTGACGTGGAAGATCCTTATGAACAATTAGAATATATGCTAACTGAAACGAATAGC
CCTGCCTATAAAACGAGAAATGCAAGCATTCGCTTTAAAGCATCTACTCAATTTTTCGAGATGATTAGAGCGTACAGACA
ATCTCTTGAATCTTCAGGCATGCTATTTAGAGGAATGAAATTTAGAGGAAAACTGATTGTTTCTGCGAAAGAAATTACAG
AGCAATTTTACAATACCGACTCCTCCCTTCGCTTCCATAATCGAATTGAAAAGTTAACGGATTGGCTAAATAAACAAATA
GATGCAATTGAAAAAGCAGAATTGAAAAAGCCTTGGGTAGAAGATGAAATTGAATTACTTAGTAAAGATGAATACCAAGA
GGCTTATAAATACTTGCAGAAAAAAGGCGAGTTTGACGACAACTCCTTTCAAGATTTTGAGAAAGAAACGAGAGTACTTG
GACGTATGATTGTCCGTAAAAAATTGAAGCCGCTGCGTAAAGGCGTTCAAACATTACGCTTTATCAATTTCACAGGTATA
TATAAACAACTTTTCACAGATGCATCATGGGGTACTGGAGAAAAACCGAAAGAATGGGATGACATTTGCTCACTAACGGT
GAACATGCTCGATGAAGGAAAGCTATATTACGAGGATGCGACTCCATTTTTACTTTTAAAAGAGTTAATTGAAGGTTTCC
AAACGAACAGATCGATTAAACACGTACTCGTAGACGAAGCACAAGATTATTCGCCGTTTCAGTTCGAGTTTTTAAAACGT
CTCTTCCCTGCCGCAAGAATGACGGTACTTGGAGACTTTAACCAAGCAATATTTGCTCATGCGAGTGAAACAGTTAATTT
CGATACACTTACGAATTTATACGGGCCAGACGAAACAAACGGCATTAACTTAACTCGTAGTTATCGCTCAACAAAACCAA
TTATTGAATTTACACGTGCTCTCGTACCGGAAGGGAAGAACATTCACGCCTTTGAACGTGACGGTGAGAAACCTACAGTG
ACGAAAGTAGCGAATGAGAGCGAACTGCACGAACGTATTACTGCCAAAGTTGCTGAATTACAAAAACAAAATCACAACAC
GATCGCAATTATATGTAAATCTGCAGCTGAAAGCGCCGCTGCCTATGAGGCACTTAGTCCTATCGAGAATATTAAACTCG
TGAAGAGTAACTCAGCCGAGTATGAGCAAGGCATTGTCGTGATCCCAGCTTACTTAGCGAAGGGTATCGAATTTGATGCC
GTTATTATTTACGATGCGTCTAAAGATGTATACAACGATGAGAGCGTTCGTAGATTGTTCTATACTGCTTGTACGCGCGC
GATGCATGAATTACAACTTTATAGCGTTGGCGAAGTTAGTCCTTTTATTCTTGAGGCTGATTCGGAGAGTTTTGAGCTTA
TTACAACACCTTGA

Upstream 100 bases:

>100_bases
TTTATAAAACGAAAAGAACGTATTTATCCGTATCTTAATTGTACACCAAAACACATCTTCAGTCAACCTCTATTTTTCAC
TTTTAAAGGAGTGCTATCGT

Downstream 100 bases:

>100_bases
TAACAATCAAGGTGTTTTCTTTTTTATGCAGGACTTACACCTTTAAAGTAGAATATATCAGTTTAGAAAAAAGTTAAGGA
GCGAAAAGATGAACCATTAT

Product: ATP-dependent DNA helicase replicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALKRMHKSPYFGRIDFKEEGESAAEKIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHNRIEKLTDWLNKQI
DAIEKAELKKPWVEDEIELLSKDEYQEAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFILEADSESFELITTP

Sequences:

>Translated_777_residues
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALKRMHKSPYFGRIDFKEEGESAAEKIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHNRIEKLTDWLNKQI
DAIEKAELKKPWVEDEIELLSKDEYQEAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFILEADSESFELITTP
>Mature_777_residues
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALKRMHKSPYFGRIDFKEEGESAAEKIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHNRIEKLTDWLNKQI
DAIEKAELKKPWVEDEIELLSKDEYQEAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV
TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFILEADSESFELITTP

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 89364; Mature: 89364

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALKRMHKSPYFGRIDFKEEGESAAEKIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHEEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF
EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC
FRGKLIVSAKEITEQFYNTDSSLRFHNRIEKLTDWLNKQIDAIEKAELKKPWVEDEIELL
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SKDEYQEAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVANESELHERITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
QKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
HHCCCCEEEEEEECHHHHHHHHHHHCCHHHEEEEECCCCHHHCCEEEEEHHHHCCCCCCE
VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFILEADSESFELITTP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECC
>Mature Secondary Structure
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALKRMHKSPYFGRIDFKEEGESAAEKIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHEEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF
EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC
FRGKLIVSAKEITEQFYNTDSSLRFHNRIEKLTDWLNKQIDAIEKAELKKPWVEDEIELL
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SKDEYQEAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVANESELHERITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
QKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA
HHCCCCEEEEEEECHHHHHHHHHHHCCHHHEEEEECCCCHHHCCEEEEEHHHHCCCCCCE
VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFILEADSESFELITTP
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]