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The map label for this gene is blaR1 [H]

Identifier: 52144233

GI number: 52144233

Start: 1101311

End: 1103209

Strand: Direct

Name: blaR1 [H]

Synonym: BCZK0994

Alternate gene names: 52144233

Gene position: 1101311-1103209 (Clockwise)

Preceding gene: 52144236

Following gene: 52144232

Centisome position: 20.78

GC content: 32.65

Gene sequence:

>1899_bases
ATGATAGACATGCTTATAAAGGTATACCTTCCTCATTTTTTTGATTGGCTTATAGAAACGTCTCTTATGGCTAGTATATT
AGTAGGATTTATTTTATGTATAAAAATACTATTTAGAAATAAATTAACACCCCGGTGGCAATATATGCTGTGGATTGTAT
TAATGATTAGACTCCTTTTACCATGGTCACCAGATAGCTCTTATAGCATTTATTCATTACTTTCTTATCGTTCTAGTGTA
TCGGAAGTTATTCCTAAAAATATGCCGTCTACTGAGAGTATGATGAACATAGAAAGCGACCATAAAGTGGAATTAGAATC
ACATGCTGAAACCGTTACAAAAAGTGGTAAACCTGAAGTAAACGTAAGTACGGAGCAACAGACTCCATTTTCTTTATACA
AACTTGCTATGTATGTTTGGTTAGTTGGGGTATTCCTATTAGCAGTTATAACGTTTATTACAAATAGACGTTTATATTCT
TACATAAAGAAACAACCGGATATTACGGATGAACAGGTTGTTACGGTGTTTAATCGCTGTAAGCAGTCTATGAAAATGAA
GAAGGCAGTTTCATTACGTTTAGCAGGAAAGATTGCGAGTCCAACTGTGTTTAGTTTCTTTCGCCCGAAAGTATTACTAT
CAAAAAAACATATGAAAGTATTAAACGAGCAACAACTACAATATGTCTTTTACCATGAGTTAGCTCATATTAAGAGAAAC
GACGTAGCTGTAAATTGGATTATGTACAGCTTAATTCTATTAAATTGGTTCAATCCGATTCTTTGGTACGCCTATTTTTG
TATGCGAGAAGATCAAGAATTAGCCTGTGATGCATATGCACTTACGTTTATAGATAAAGAAGAGCAAATTGCATATGGTC
ATACAATTATTACCCTTTTAGAACACTATTCCTATCAAGCGCCAAGTCTAGCAAATTTAAGTAGAAATAAACGAACACTG
AAAAGGAGAATCGTTATGATTAAAAGGTTTCAAAAGAAATCGTATCGTCTTTCTTTACTGGGAGTTATTGTCATAGTTGC
TATTGCATCCCTTTCTTTATTCAATGCACGTGCAACGGAAGGGAAAGAAAAACAAGAGGATAAAGTAGAGCAGTCAAAGG
ATGCTTTCCAAAATGCTGTAGATATGCTGTATGGTACAGAAGAAAATGCGAAAAAAGAATATCATTATTCAGCAAGAGTG
TATGAAGAAAAGACAGATTACTTATATTTAGCTGAAAAGGCTTTAACAAAAGATGAATTCCAGCAGTACATAAAATTATC
TAAAAAAATTATTAATATACAGAAAAAAGGTGCTCCGAGAGATTCTGACTACGAGTCAACAGTTTTTAGAGAAGAGCGTT
TATCAAAAGCTGATCGTGACAAATTATATGCACTTTATGATCAAGCAAAACCATTTGATGACAAAGTATACGAATCTTTA
AATTACACGGTAAAGGAAGCGCAACAACATGTTGATTTTCAAATTAAGAAGCCAACGTACACAATTGAAGGATACAATCT
GAAGGATGAAAATGTAGGTTATTTTATTAAGAGAAGACCTGAATTAATTATTGAATTAGAGTATACAAACGGAAAAGGAA
ACTATACAATTTATCAATCACAAGTATTTGGAGAAAGTAAAGATCCATTTAGTCACCAGTTTGTAGTACCTGAAAATATA
GAACAGTACGAATTAGAAGGGAATCAAATATTCTACGCTACTGATCACTCGGATAGTAATTTACAAGGTATAAAGATGAT
TGTTCCAGCAAAAGGGAAAAATAGTGCATACCAAGTTGTTATTATTAATCATAGTTTAGAGCGTCAAGGAGAAGCAGTAT
TTGATAAAAATGTAAATAAGGAAGAGTTAGAGAAGATTATGATTTCTATGTTGAAATAA

Upstream 100 bases:

>100_bases
ATTTCTTAAAAGAGGAAAAATTGTCTTCAGAAGATATTAACGAACTAAAACGCATTTTAGACGAGAAGACCGAGGAGAAT
AAGAGGAAGGATTGATAAAA

Downstream 100 bases:

>100_bases
TAAAAAGGTGTTCTAGAGATGTATATCTTAAGAACACCTTTTCCTTTTCTCTTTTCTTCTGATAAACTATGGAAAGTATG
ATATAACTTGACTGAAATTT

Product: beta-lactamase regulatory protein 1; methicillin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MIDMLIKVYLPHFFDWLIETSLMASILVGFILCIKILFRNKLTPRWQYMLWIVLMIRLLLPWSPDSSYSIYSLLSYRSSV
SEVIPKNMPSTESMMNIESDHKVELESHAETVTKSGKPEVNVSTEQQTPFSLYKLAMYVWLVGVFLLAVITFITNRRLYS
YIKKQPDITDEQVVTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNEQQLQYVFYHELAHIKRN
DVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEEQIAYGHTIITLLEHYSYQAPSLANLSRNKRTL
KRRIVMIKRFQKKSYRLSLLGVIVIVAIASLSLFNARATEGKEKQEDKVEQSKDAFQNAVDMLYGTEENAKKEYHYSARV
YEEKTDYLYLAEKALTKDEFQQYIKLSKKIINIQKKGAPRDSDYESTVFREERLSKADRDKLYALYDQAKPFDDKVYESL
NYTVKEAQQHVDFQIKKPTYTIEGYNLKDENVGYFIKRRPELIIELEYTNGKGNYTIYQSQVFGESKDPFSHQFVVPENI
EQYELEGNQIFYATDHSDSNLQGIKMIVPAKGKNSAYQVVIINHSLERQGEAVFDKNVNKEELEKIMISMLK

Sequences:

>Translated_632_residues
MIDMLIKVYLPHFFDWLIETSLMASILVGFILCIKILFRNKLTPRWQYMLWIVLMIRLLLPWSPDSSYSIYSLLSYRSSV
SEVIPKNMPSTESMMNIESDHKVELESHAETVTKSGKPEVNVSTEQQTPFSLYKLAMYVWLVGVFLLAVITFITNRRLYS
YIKKQPDITDEQVVTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNEQQLQYVFYHELAHIKRN
DVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEEQIAYGHTIITLLEHYSYQAPSLANLSRNKRTL
KRRIVMIKRFQKKSYRLSLLGVIVIVAIASLSLFNARATEGKEKQEDKVEQSKDAFQNAVDMLYGTEENAKKEYHYSARV
YEEKTDYLYLAEKALTKDEFQQYIKLSKKIINIQKKGAPRDSDYESTVFREERLSKADRDKLYALYDQAKPFDDKVYESL
NYTVKEAQQHVDFQIKKPTYTIEGYNLKDENVGYFIKRRPELIIELEYTNGKGNYTIYQSQVFGESKDPFSHQFVVPENI
EQYELEGNQIFYATDHSDSNLQGIKMIVPAKGKNSAYQVVIINHSLERQGEAVFDKNVNKEELEKIMISMLK
>Mature_632_residues
MIDMLIKVYLPHFFDWLIETSLMASILVGFILCIKILFRNKLTPRWQYMLWIVLMIRLLLPWSPDSSYSIYSLLSYRSSV
SEVIPKNMPSTESMMNIESDHKVELESHAETVTKSGKPEVNVSTEQQTPFSLYKLAMYVWLVGVFLLAVITFITNRRLYS
YIKKQPDITDEQVVTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNEQQLQYVFYHELAHIKRN
DVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEEQIAYGHTIITLLEHYSYQAPSLANLSRNKRTL
KRRIVMIKRFQKKSYRLSLLGVIVIVAIASLSLFNARATEGKEKQEDKVEQSKDAFQNAVDMLYGTEENAKKEYHYSARV
YEEKTDYLYLAEKALTKDEFQQYIKLSKKIINIQKKGAPRDSDYESTVFREERLSKADRDKLYALYDQAKPFDDKVYESL
NYTVKEAQQHVDFQIKKPTYTIEGYNLKDENVGYFIKRRPELIIELEYTNGKGNYTIYQSQVFGESKDPFSHQFVVPENI
EQYELEGNQIFYATDHSDSNLQGIKMIVPAKGKNSAYQVVIINHSLERQGEAVFDKNVNKEELEKIMISMLK

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 74030; Mature: 74030

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEECCHHHCCCCHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure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EEECCHHHCCCCHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]