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The map label for this gene is aroB [H]

Identifier: 52143830

GI number: 52143830

Start: 1487858

End: 1488943

Strand: Direct

Name: aroB [H]

Synonym: BCZK1399

Alternate gene names: 52143830

Gene position: 1487858-1488943 (Clockwise)

Preceding gene: 52143832

Following gene: 52143831

Centisome position: 28.07

GC content: 37.85

Gene sequence:

>1086_bases
ATGGGAAACATACATATTCAAACGAAATCAAAAGAATATGATGTATATGTAGGAAAAGAATCGTTGTCACATTTGACAAC
AATCGTTCAAAACATGCAGCCATCTGTATCAAATATTATGATCATTTCAGATGAAGCTGTTGCCTCTTTACATTTACAGA
CAGTTGTAGACGCGTTGCAAATAGATCGAAAAGTATTTTCATTCGTTGTACCGAGTGGTGAAAAAGAGAAGTCCTTTGAA
AATTTCTATGCGGCTCATACGTCAGCTCTTGAAAATAAATTAGATAGAAATTCTTTAATTGTTGCACTTGGAGGTGGGAT
GATTGGAGATTTAGCTGGTTTTGTTGCTGCGTCGTTTATGCGTGGAATTCGCTTTGTTCAAGTTCCGACGACTTTATTAG
CTCACGATAGCGCGGTAGGTGGGAAAGTAGCAATCAATCATCCGTTAGGTAAAAATATGATAGGTGCATTCCATCAACCG
GAAGCAGTTGTATATCATACGCCATTTTTACAGTCTCTTCCTGAAAAAGAGTGGCGCTCAGGTTATGCAGAAGTGATAAA
ACATGCTCTAATTGGTGATGTAAAGCTATATCATTGGCTAAAAGAAGACGTGCAAACATTAGCAGATCTTCGTGATGAGA
AATTAATCCACATATTAACGAAGGCAATTCCTGTAAAGGCAAACATTGTAGCGCAAGATGAAACAGAAAAAGGTGTACGT
GCTCATTTAAACTTTGGGCATACGTTAGGCCATGCTCTCGAAAAAGAACTAGGATACGGAAATATTACTCACGGTGATGG
AGTAGCGGTTGGAATGTTATTTGCTATATTCTTAAGTGAACAAGTGTATAAGGTGAATCTTGCTTATGAAGAGATGAAGC
AGTGGTTCTTGAAGTACGGCTATCCAAAAATGCCAAGTGATTTAAGTGTAGAACGCCTCGTTCAATTGATGAAACAAGAT
AAGAAAGCGAATGCAGGGACAATTCATATGGTACTTATGCAGGAATATGGGGTAGTGAATGTCGTATCTATTCCTGATGA
GACTGTTCATATTGCGTTAGAGGCATTTCAAAAGGATATGTTTTAA

Upstream 100 bases:

>100_bases
GGGAATTAGCGACAGCTTTAATAGAACAATTCGGATTAGATCGTATGGACCTTATTCGTGAAAATATTGAGAAACATAAT
GAATATGCGAGGGGATTTTA

Downstream 100 bases:

>100_bases
AAATAAATGATAGAAAGTAGCCATGAAGTGCTTATTTTGAGGTGTTTTCGTAATAGTGACGGTTAGGATAAAAGATTACA
GTAAAGGACTAAAATTGTAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDRKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEDVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVQLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMF

Sequences:

>Translated_361_residues
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDRKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEDVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVQLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMF
>Mature_360_residues
GNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQIDRKVFSFVVPSGEKEKSFEN
FYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPE
AVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEDVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVRA
HLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVQLMKQDK
KANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=313, Percent_Identity=43.1309904153355, Blast_Score=234, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=32.5268817204301, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40139; Mature: 40008

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQ
CCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHH
IDRKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEDVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVQLMKQDKKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHCC
F
C
>Mature Secondary Structure 
GNIHIQTKSKEYDVYVGKESLSHLTTIVQNMQPSVSNIMIISDEAVASLHLQTVVDALQ
CCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHH
IDRKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIVALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEDVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVQLMKQDKKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA