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The map label for this gene is ywcA [H]

Identifier: 52143754

GI number: 52143754

Start: 1572771

End: 1574321

Strand: Direct

Name: ywcA [H]

Synonym: BCZK1480

Alternate gene names: 52143754

Gene position: 1572771-1574321 (Clockwise)

Preceding gene: 52143753

Following gene: 52143752

Centisome position: 29.67

GC content: 39.59

Gene sequence:

>1551_bases
TTGAATACGACTGCATTTGCACTATTTTTAATTATTGTCCTTGGTACGCTCGTCATAACCTATTTTGCATCGAAAAAAAC
GAAAAATGCGAGTGAGTTTTATACAGCTGGAGGGGGATTAACTGGTTGGCAAAATGGTCTGGCCATTGCGGGGGATTATA
TGTCTGCTGCTTCTTTTCTTGGTATAGCGGGAGCGATCGCATTAACTGGGTTTGATGGTTTCTTTTATAGTATCGGCTTT
TTAGTTGCTTATTTAGTTGTTCTATACCTTGTCGCAGAACCGCTAAGGAATTTAGGGAAGTATACGTTAGCGGATATGAT
TGCGGCGCGTTTTGATGCGAAAAAAGTTCGCGGAGTTGCAGCGCTTAATACGATGACGATTTCAATTTTTTATATGATTG
CACAATTAGTTGGGGCGGGTGCACTTATTAAGTTATTATTAGGGATCGAATATACAACATCCGTTTTAATTGTTGGTACA
TTAATGACAGTGTACGTTATTTTTGGCGGAATGACCGCGACGAGCTGGGTACAAATTGTTAAGGCTGTATTACTTATGGC
TGGTACATTTATTATTTCTGTTATCGTTTTCGCAAAATTTAATTTCAGTGTGACGGAAATGTTTGCGCAAATGAAAACAG
CTACTCCGTTAAAAGAGTCGTTTTTAAATCCCGGTGTAAAGTATAAGGATGGTCTTGATACACTATCTTTAAATTTAGGA
CTAGTCCTTGGTACGGCAGGATTACCACACATTCTTGTTCGCTTTTTTACAGTACGTGATGCAAAAACAGCACGTCAATC
TGTAGTATACGCTACGTGGTTAATTGGCGCATTTTATATTATGACAATTTTCTTAGGATTTGGGGCAGCGGCGTTTGTAG
GGAATGAGGCGATTATGAAAGCAAACCCTGCTGGTAATATGGCAGCACCTTTATTAGCGAAAGCATTGGGCGGAGATTTC
TTATTTGCTTTCGTATCAGCAATTGCCTTTGCAACGATTTTAGCTGTAGTGGCAGGCCTTGTATTAACAGCAGCATCAGC
ATTCGCACATGATTTTTATAACGAAATTATCCGCAAGGGGAAATCAACGGAAAAAGAGCAAGTATCCATGGCTCGTTATG
CGTCTATTGGAGTAGCGGTATTATCTATTATACTAGCGTTATTTGCTCAAACATTGAACGTAGCATTTTTAGTTTCGTTA
GCATTTGCAGTTGCAGCGAGTGCAAACTTGCCAGTTATATTATTCACAATATATTGGAAGCGCTTCAATACAACAGGTGC
CATTTCGGGTATGATTGTTGGTCTAGTATCAGCCATTGTTCTTGTAGCGTTAAGCCCAAATGTTTGGAACCCTGTAGCTG
GAAAAGCTATATTTGTTGGGGAAGCGATATTCCCATATACGACACCTGGAATTATTTCGATCCCGCTCGGATTTCTTGCA
GCATATTTAGGAACCGTGTTATCTAGTAAGAAAGAAGATGCGGCGAAATTTGATGAAATTCTTGTGAAATCAAATACTGG
TCATGGTATTAGTGATGCGTCTTCGCATTAA

Upstream 100 bases:

>100_bases
TGACTTGGGCTTTATGTATGATTTATAGCAAAAAGGCGGAATCCTTTGATGAAATCTCGCAAAAAATTCTACAAAATATG
CAAAAAGGGAGGGGCTGAAC

Downstream 100 bases:

>100_bases
AAAAGAGGAGCTTTTCGATAGATAAGAAAAGCTCCTTTTTCTTTTGTCCTTTTCTTGTAAATAATACTGCTTTGTAAGTA
GGATTTGTCTTAATTTTGTG

Product: sodium/solute symporter family protein; sodium/proline symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNTTAFALFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTATPLKESFLNPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVGNEAIMKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKSTEKEQVSMARYASIGVAVLSIILALFAQTLNVAFLVSL
AFAVAASANLPVILFTIYWKRFNTTGAISGMIVGLVSAIVLVALSPNVWNPVAGKAIFVGEAIFPYTTPGIISIPLGFLA
AYLGTVLSSKKEDAAKFDEILVKSNTGHGISDASSH

Sequences:

>Translated_516_residues
MNTTAFALFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTATPLKESFLNPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVGNEAIMKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKSTEKEQVSMARYASIGVAVLSIILALFAQTLNVAFLVSL
AFAVAASANLPVILFTIYWKRFNTTGAISGMIVGLVSAIVLVALSPNVWNPVAGKAIFVGEAIFPYTTPGIISIPLGFLA
AYLGTVLSSKKEDAAKFDEILVKSNTGHGISDASSH
>Mature_516_residues
MNTTAFALFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTATPLKESFLNPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVGNEAIMKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKSTEKEQVSMARYASIGVAVLSIILALFAQTLNVAFLVSL
AFAVAASANLPVILFTIYWKRFNTTGAISGMIVGLVSAIVLVALSPNVWNPVAGKAIFVGEAIFPYTTPGIISIPLGFLA
AYLGTVLSSKKEDAAKFDEILVKSNTGHGISDASSH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=452, Percent_Identity=24.5575221238938, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1790503, Length=524, Percent_Identity=46.3740458015267, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1787251, Length=455, Percent_Identity=27.4725274725275, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87082237, Length=459, Percent_Identity=23.3115468409586, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648033, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356865, Length=390, Percent_Identity=24.8717948717949, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54583; Mature: 54583

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]