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The map label for this gene is cat1 [H]

Identifier: 52143557

GI number: 52143557

Start: 1770189

End: 1771703

Strand: Direct

Name: cat1 [H]

Synonym: BCZK1678

Alternate gene names: 52143557

Gene position: 1770189-1771703 (Clockwise)

Preceding gene: 52143556

Following gene: 52143555

Centisome position: 33.39

GC content: 38.81

Gene sequence:

>1515_bases
ATGGAGAATAATTTGGATAGAATTAGGGATCAACGTCTGAAAGATCGCGTAGTTACACCTGAAGAAGCAGCTTCATGGAT
TGAAAGTGGAATGACTTTAGGCTTAAGTGGGTTTACACGTGCAGGTGATGTGAAAGCAGTCCCATTTGCGCTTGTAAACC
GAGTTAAGAATGATACATCTTTTAAAGTAAATGTTTATACTGGTGCCTCTTTAGGTTCTGATGTAGATAAATTATTTGCG
GAAGCAGGAATTTTAGGGAAAAGATTGCCTTTCCAAGCTGATGCGACTATGCGAAAAGGAATTAATAACGGAGATTTTTT
ATTTGTGGACCAGCACTTATCTCATACAGCAGAGTTACTTCGCGCTGACGTTATGGATGTAGATTTTGCTATTTTGGAAG
CGGTTGCGATTACTGAAGATGGGATGATTATTCCAACGACTTCAATAGGAAATTCTTTAGCGTTTTCTTTAAATGCTAAG
TCCATCATTATTGAAATGAATATGGCTCAATCCGCACAGTTAGAAGGACTGCATGATTTATATGAACCAGGTAAGCAGGG
AGAAAGGCTTCCAATTCCGATTGTGAAAACGGATGATCGAATTGGAACGATTGGCATTCCAATCGATGTTGAAAAGGTGA
AAGGGATTGTGTTTACGAACCAATTAGACTCACCATCGACAATTGTTCCTCCGGATGAAGAAACTGTTATTATGGCACAG
CATTTAATAGAGTTCCTTCGAAAAGAAGTCGAAGTAGGCCGATTAACAAATCGTTTAGCACCGTTACAATCGGGAATTGG
TTCAGTGGCTAATGCAGTTCTTCATGGAATGTTAGATTCGGAGTTTGAAGATTTAGAAGTGTATTCTGAAGTTTTACAGG
ATGCGGTCTTTGATCTTATGGATGCTGGAAAAGTCAATTTTGCTTCATGCTGCTCGATCACACTTTCTGAGGAGAAAATG
CAAAAAGTATTTTCTAACTTTGAAAAATATCGTGACAAATTAATGATGCGCCCGCAAGAGATTTCCAATCATCCTGAAAT
CATTCGTCGCCTCGGATTAATCTCGATTAATACGGCTTTAGAACTAGATATATACGGAAATGTGAACTCTACTCACGTTT
TAGGTACAAAAATGATGAATGGTATTGGTGGTTCTGGTGATTTTGCGAGAAATGCACGCCTAGCTATCTTTGTTACGAAA
TCGATTGCGAAAGGCGGTAACATTTCAAGTATCGTTCCTTTCGTATCTCATGTAGATCATACGGAACATGATGTAGATGT
TATCGTCACTGAGCAAGGATATGCTGACTTAAGAGGACTTGCGCCAAGTGAAAGAGTGGAACTCATTATTGAGAATTGTG
CACATCCAATGTATCGTGACCAGTTACGAGCTTATTATGAGGAAGCAAAAACAAGAGGTGGACAAACTCCTCATATTTTA
GAGAAAGCTTTTTCTTGGCATACGAATTATGCTAAAAAGGGAACTATGCTTGAAGCAGTAGTAGAAACTGTATAG

Upstream 100 bases:

>100_bases
CTGTTTTGTCTGAATTTTTGCCATTATATACTGAAATCCCTATTTGGATACTGTTAAAGTGTAAAATAATTATGAATATT
CATAAGGAGAGGGATTACAT

Downstream 100 bases:

>100_bases
GTGTGTATCGTTAGAAATAGTAAAACGAAAGATTGAGTTTGAAAAAATTTTAGAAGAAGAAAACGCCAACTTTCAAAGAT
GGCGTTTTTTTCTTTAAATA

Product: succinyl-CoA: coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKKGTMLEAVVETV

Sequences:

>Translated_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKKGTMLEAVVETV
>Mature_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKKGTMLEAVVETV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=42.3868312757202, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17538151, Length=397, Percent_Identity=26.1964735516373, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319456, Length=510, Percent_Identity=42.3529411764706, Blast_Score=398, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55581; Mature: 55581

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSAQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHCCHHHH
YEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCEEEECCCCEEEEECCEEHHHHCCEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFVSHVDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKKGTMLEAVVETV
HHHHHHHCCHHCCCHHHHHHHHCC
>Mature Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSAQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHCCHHHH
YEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCEEEECCCCEEEEECCEEHHHHCCEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFVSHVDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPSERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKKGTMLEAVVETV
HHHHHHHCCHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]