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The map label for this gene is lytT [H]

Identifier: 52143556

GI number: 52143556

Start: 1769417

End: 1770061

Strand: Direct

Name: lytT [H]

Synonym: BCZK1677

Alternate gene names: 52143556

Gene position: 1769417-1770061 (Clockwise)

Preceding gene: 52143558

Following gene: 52143557

Centisome position: 33.38

GC content: 35.66

Gene sequence:

>645_bases
ATGGAAGATAAAACATTAGGTTTACTACTAGATGTTGTTGGGGAATTATTTTCAGATGAAATTTCAATTGCTGTATCGAA
TACGAAGGAATATATATACTATCGGCCAAGTAAACGAATTGATTTAAAGATTAGCGTAGGGGATCCTATTAAGGAAGGAA
CAATTGCTCATAAAGCAATGGTGACAAACCAAAAAACCTCGGAGTTTATTAACCGGGATGTTTTTGGTATTCCTTATCAT
GGTATGGCAGTGCCATTTTCAAACAATGGAAAGCTTGAAGGTTGCGTGACAGCTATTTACCCAGCTTTAACGGATGGAAA
GTCAGTCGTTACTTTAAAAACAACGGACGGCTGGGTTCCGGTTCCTTTCTCAAAGGTCATGTATTTAGAGGCGAAAGATA
AAAGGACGTATGTAAATGCAGAAGAGTTAACAGGAACACATAAATACTCTCTACAAGAATTCGAATACTTACTTCCGAAA
GATTCATTTATTAGATGTCACCGTTCATTTATCGTAAATGTTAATCATATTAAAGCGATTTATCCTGATACGCATTCTAC
TTTTTTACTTTCTATGGATAATGGAGAGAGGGTCCCAGTTAGTCAATCATACGCTAGTTATTTTCGTAAACTTCTAGGAT
TTTAA

Upstream 100 bases:

>100_bases
CTGCTTCAGAACTTTAAGAACAATTTCTAATCAAACTTCTTATAAAGCAACTGATGCTCGTTCATAATAGTAGTATAATA
GTGAATGAGGTGTTAATAGG

Downstream 100 bases:

>100_bases
ATTATTCTGCTTTAGAGATTAGATTCGCTGTTTTGTCTGAATTTTTGCCATTATATACTGAAATCCCTATTTGGATACTG
TTAAAGTGTAAAATAATTAT

Product: transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEDKTLGLLLDVVGELFSDEISIAVSNTKEYIYYRPSKRIDLKISVGDPIKEGTIAHKAMVTNQKTSEFINRDVFGIPYH
GMAVPFSNNGKLEGCVTAIYPALTDGKSVVTLKTTDGWVPVPFSKVMYLEAKDKRTYVNAEELTGTHKYSLQEFEYLLPK
DSFIRCHRSFIVNVNHIKAIYPDTHSTFLLSMDNGERVPVSQSYASYFRKLLGF

Sequences:

>Translated_214_residues
MEDKTLGLLLDVVGELFSDEISIAVSNTKEYIYYRPSKRIDLKISVGDPIKEGTIAHKAMVTNQKTSEFINRDVFGIPYH
GMAVPFSNNGKLEGCVTAIYPALTDGKSVVTLKTTDGWVPVPFSKVMYLEAKDKRTYVNAEELTGTHKYSLQEFEYLLPK
DSFIRCHRSFIVNVNHIKAIYPDTHSTFLLSMDNGERVPVSQSYASYFRKLLGF
>Mature_214_residues
MEDKTLGLLLDVVGELFSDEISIAVSNTKEYIYYRPSKRIDLKISVGDPIKEGTIAHKAMVTNQKTSEFINRDVFGIPYH
GMAVPFSNNGKLEGCVTAIYPALTDGKSVVTLKTTDGWVPVPFSKVMYLEAKDKRTYVNAEELTGTHKYSLQEFEYLLPK
DSFIRCHRSFIVNVNHIKAIYPDTHSTFLLSMDNGERVPVSQSYASYFRKLLGF

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=119, Percent_Identity=32.7731092436975, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24192; Mature: 24192

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKTLGLLLDVVGELFSDEISIAVSNTKEYIYYRPSKRIDLKISVGDPIKEGTIAHKAM
CCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHH
VTNQKTSEFINRDVFGIPYHGMAVPFSNNGKLEGCVTAIYPALTDGKSVVTLKTTDGWVP
HCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHEEEHHHHCCCCEEEEEEECCCEEE
VPFSKVMYLEAKDKRTYVNAEELTGTHKYSLQEFEYLLPKDSFIRCHRSFIVNVNHIKAI
CCHHEEEEEEECCCEEEECHHHHCCCCCCCHHHHHHHCCCHHHHHEEHHHEEEEHHEEEE
YPDTHSTFLLSMDNGERVPVSQSYASYFRKLLGF
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEDKTLGLLLDVVGELFSDEISIAVSNTKEYIYYRPSKRIDLKISVGDPIKEGTIAHKAM
CCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHH
VTNQKTSEFINRDVFGIPYHGMAVPFSNNGKLEGCVTAIYPALTDGKSVVTLKTTDGWVP
HCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCHHHEEEHHHHCCCCEEEEEEECCCEEE
VPFSKVMYLEAKDKRTYVNAEELTGTHKYSLQEFEYLLPKDSFIRCHRSFIVNVNHIKAI
CCHHEEEEEEECCCEEEECHHHHCCCCCCCHHHHHHHCCCHHHHHEEHHHEEEEHHEEEE
YPDTHSTFLLSMDNGERVPVSQSYASYFRKLLGF
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]