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The map label for this gene is fabH [H]

Identifier: 52143487

GI number: 52143487

Start: 1872596

End: 1873591

Strand: Direct

Name: fabH [H]

Synonym: BCZK1748

Alternate gene names: 52143487

Gene position: 1872596-1873591 (Clockwise)

Preceding gene: 52143486

Following gene: 52143485

Centisome position: 35.33

GC content: 37.35

Gene sequence:

>996_bases
ATGAATATTGGGATTGAAGCGACCGGTGTTTTCTTCCCAAAAGATGTAGAGACGGCCGTAGACTTATCTCAAAAAACAGG
TATTCCTGAGAATGTTATTATAGAAAAATTTGGGTTGTATGAAAAACATGTTGCAGATGAAACGATGCATGCATCAGATT
TAGCTATTGCTGCTGCAAAGCCAATATTATTACAAGTAAATCCTCAGTCTATTGATGTAGTCATTTATTTTGGCAGTCCA
CATAAAGATTACCACGTATGGTCTAGTGCCCCAAAAATTCAGCATGAACTTGGATTGAAAAATGCTTATGCTTTTGAAAT
TATGAATGTTAGTTCTTGCTTTCCAATTGCTCTCAAAGTCGCAAAAGACATGCTTTACTCCGATAACTCAATTGAAAATA
TATTATTAGTAGGTGGATGTAAAGAATCTCAAATTGTAGATTATGATAATCCACGCTCGCGTTTTATGTTTAATTTCGCT
GATGGCGGAAGTGCAGCTTTAGTGAAAAAAGACGCTAAAAACGGTGAAATATTAGGAAGTGCGATAATAACAGATGGTTC
ATTTCATGAAGATGTTCGTATCCCAGCTGGTGGATCAAAGCAGGTTGCGAGCTATGATACAGTTGAGAATCGACAACATT
ATATTGATGTAATAGATCCTAATAGTATGAAAGAACGTCTAGACCCGATTTCAATCCCTAATTTTGACAAGGTTATTCGG
GAGGCGTTAAGAAAAAGTGGATATACTCCTAAAGATATTAAAGTATTGTTACCACTGCATACAAAACGTTCTATGTTAAT
AGAATTGATACAGGGGCTAGGGCTAACGGAAGAACAAGTCGTATATTTAGATCATTATGGGCATATGTCAGCGCTTGATC
CGTGTATTGGTCTTCACTTTGCAAATGAACAAGGAAAATTACAGGCCGGAGATATTGCAGTAGTAGTTAGTGCAGGGACT
GGGTATACATGGGCAGCGACTGTGATTAGGTGGTGA

Upstream 100 bases:

>100_bases
GAGTTTTGAAATTGTTAACGGAGTGTCATAACCAAAAAGGAAATCTAGTATTAACAGGTGTAGCTACTATGATGGTGCCA
AAAGAAGGAGGAATAGTCTA

Downstream 100 bases:

>100_bases
AAAATTCTAAATGAACATATGAGAAATGGAGGTATTTGGAAAGGAGCGGCGAATGTAATGGTACTTCATTAAATTTTCTC
AACAGATTTGTTTGTATGAT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MNIGIEATGVFFPKDVETAVDLSQKTGIPENVIIEKFGLYEKHVADETMHASDLAIAAAKPILLQVNPQSIDVVIYFGSP
HKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKVAKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFA
DGGSAALVKKDAKNGEILGSAIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHFANEQGKLQAGDIAVVVSAGT
GYTWAATVIRW

Sequences:

>Translated_331_residues
MNIGIEATGVFFPKDVETAVDLSQKTGIPENVIIEKFGLYEKHVADETMHASDLAIAAAKPILLQVNPQSIDVVIYFGSP
HKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKVAKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFA
DGGSAALVKKDAKNGEILGSAIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHFANEQGKLQAGDIAVVVSAGT
GYTWAATVIRW
>Mature_331_residues
MNIGIEATGVFFPKDVETAVDLSQKTGIPENVIIEKFGLYEKHVADETMHASDLAIAAAKPILLQVNPQSIDVVIYFGSP
HKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKVAKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFA
DGGSAALVKKDAKNGEILGSAIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHFANEQGKLQAGDIAVVVSAGT
GYTWAATVIRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=337, Percent_Identity=23.7388724035608, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36448; Mature: 36448

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIEATGVFFPKDVETAVDLSQKTGIPENVIIEKFGLYEKHVADETMHASDLAIAAAK
CCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCCCCCCCEEEEECC
PILLQVNPQSIDVVIYFGSPHKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKV
CEEEEECCCEEEEEEEECCCCCCEEEECCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHH
AKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFADGGSAALVKKDAKNGEILGS
HHHHHCCCCCCCEEEEEECCCCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEE
AIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EEEECCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCCCHHHHHH
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHF
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHEEEEEECCCCCHHCCHHHEEEE
ANEQGKLQAGDIAVVVSAGTGYTWAATVIRW
ECCCCCEEECCEEEEEECCCCCEEEEEEEEC
>Mature Secondary Structure
MNIGIEATGVFFPKDVETAVDLSQKTGIPENVIIEKFGLYEKHVADETMHASDLAIAAAK
CCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCCCCCCCEEEEECC
PILLQVNPQSIDVVIYFGSPHKDYHVWSSAPKIQHELGLKNAYAFEIMNVSSCFPIALKV
CEEEEECCCEEEEEEEECCCCCCEEEECCCCCHHHHHCCCCEEEEEEEECCCCHHHHHHH
AKDMLYSDNSIENILLVGGCKESQIVDYDNPRSRFMFNFADGGSAALVKKDAKNGEILGS
HHHHHCCCCCCCEEEEEECCCCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEE
AIITDGSFHEDVRIPAGGSKQVASYDTVENRQHYIDVIDPNSMKERLDPISIPNFDKVIR
EEEECCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCCCCCHHHHHH
EALRKSGYTPKDIKVLLPLHTKRSMLIELIQGLGLTEEQVVYLDHYGHMSALDPCIGLHF
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCHHEEEEEECCCCCHHCCHHHEEEE
ANEQGKLQAGDIAVVVSAGTGYTWAATVIRW
ECCCCCEEECCEEEEEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]