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The map label for this gene is yisV [H]

Identifier: 52143430

GI number: 52143430

Start: 1930872

End: 1932317

Strand: Direct

Name: yisV [H]

Synonym: BCZK1804

Alternate gene names: 52143430

Gene position: 1930872-1932317 (Clockwise)

Preceding gene: 52143436

Following gene: 52143425

Centisome position: 36.43

GC content: 33.68

Gene sequence:

>1446_bases
ATGATGGAAAGATTCGTTTGGAAACCGAATATGTCTCTAGCGACTCCTCTATATAAACAAATAGAAACGTATATTAAGGA
AAGAATCGTTAATGGTAAATGGACTGTTGGAACGAAATTACCTTCGCAAAGAGATTTGGCACATATATTTGGTGTGAACC
GGAGTACAATTGTAATGGCTTTCGATGAACTAGCGGCAAAGGGGTATATTGAAGGGAATGGCAGAAAAGGAACAATTGTT
GTAAATAATAATGAGAATGCTTCAATATACGCCCCCCCGCCTAATTGGCAGTCTTATGTAGAAACAGGACTTCATTATCC
AAATCTGCCTGCTATTCAAGAAATTAATCAAGCTGAATTTTATCCGCATGTAATTCGTTTAGGAACAGGTGAACTCGCGC
CAAGTCTTTTACCTGAAAAAAAGATGAAAGATATTATGAATAAGCTTTTAAAGTCGAACATGATACTTGGATATGAAGAA
CCGAAAGGGAATTTTTATTTAAGGAAGAAAATTGCGGACTATTTAAAAGGACATGGTGTATATGTAACTCCTGATTCTAT
ATTAATTGTTTCAGGGGCAATTCAAGCGTTGCAACTTATTTCTATGGGGCTTCTACCAAAAGGGGCATCTATCTTATTAG
AAAAACCATCTTATTTATATTCTCTTAATGTTTTTCAATCAGCAGGAATGCGATTAATTGGTATACCGATGGATGAAAAC
GGTTTACATCCATCATATATTCCAAAATATAAGAAGCAATTTAATGCATCTATTTTATATACAATCCCGTCTTTTCATAA
TCCGACGAACTTTAGTATGAATGCGAAGAAACGGATAGAAGTAATGGAAATATGTAATGAAATTGGATTGCCTATTATAG
AGGACGCGGTATATCAAGACTTATGGTTTGATAAGCCTATTTCAAAGCCTTTAAAGGCATATGATAAAAACGGAATTGTA
CTACATATCGGGAGTATGTCTAAAGTCATTAGTCCAGGATTAAGAATCGGATGGATTGTTGGATCAGAGCCAGTCATTCA
AAGATTGGCAGATATAAAAATGCAAACGGATTATGGCTCGAGTTCAATATCTCAGCAAATTGCAGCGGAATGGTTTGCAA
ATGGATTGTATGATGAACATTTACTGTTTGTAAGAATTCAGTTGAAAAAACGTAGAGATTTTATGTTAAAAATGTTAGAG
AAATATTGTTGTGATATAGCAACTTGGTATGAACCAGTAGGTGGTTTTTATATTTGGTTACATATGAATGTACCCGTTTC
AAACCGTAGCTTATTTGACAAAGCTTTGAAAGAAAAGATTTTATTAAATCCAGGTACTTTGTATGATAGAAGTGCAAATC
AATTTTTGCGCTTATCATATTCATACGCAACATTAGAAGAAATTGAAATAGGTATAAAAAAACTTGCAAAATTAATGAAA
AAGTAA

Upstream 100 bases:

>100_bases
TTAAATTTATTATGATAGTGTATATTGTATAGAAGAAATGAAGATTTGTATCCATCCATATGGTTGGGGAGGTTACCAAC
CAAAAAGAATATAAGGTGAT

Downstream 100 bases:

>100_bases
GAGGAGAAAGTAATGAAACAATATGTAATTTGCCAAATTATCAATGGAGAAAAATATTTAGCTGCTTATGCGGAGACGAA
GCAGGAGGCGATTGAAAAAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MMERFVWKPNMSLATPLYKQIETYIKERIVNGKWTVGTKLPSQRDLAHIFGVNRSTIVMAFDELAAKGYIEGNGRKGTIV
VNNNENASIYAPPPNWQSYVETGLHYPNLPAIQEINQAEFYPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEE
PKGNFYLRKKIADYLKGHGVYVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGIPMDEN
GLHPSYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDLWFDKPISKPLKAYDKNGIV
LHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSSSISQQIAAEWFANGLYDEHLLFVRIQLKKRRDFMLKMLE
KYCCDIATWYEPVGGFYIWLHMNVPVSNRSLFDKALKEKILLNPGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAKLMK
K

Sequences:

>Translated_481_residues
MMERFVWKPNMSLATPLYKQIETYIKERIVNGKWTVGTKLPSQRDLAHIFGVNRSTIVMAFDELAAKGYIEGNGRKGTIV
VNNNENASIYAPPPNWQSYVETGLHYPNLPAIQEINQAEFYPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEE
PKGNFYLRKKIADYLKGHGVYVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGIPMDEN
GLHPSYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDLWFDKPISKPLKAYDKNGIV
LHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSSSISQQIAAEWFANGLYDEHLLFVRIQLKKRRDFMLKMLE
KYCCDIATWYEPVGGFYIWLHMNVPVSNRSLFDKALKEKILLNPGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAKLMK
K
>Mature_481_residues
MMERFVWKPNMSLATPLYKQIETYIKERIVNGKWTVGTKLPSQRDLAHIFGVNRSTIVMAFDELAAKGYIEGNGRKGTIV
VNNNENASIYAPPPNWQSYVETGLHYPNLPAIQEINQAEFYPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEE
PKGNFYLRKKIADYLKGHGVYVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGIPMDEN
GLHPSYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDLWFDKPISKPLKAYDKNGIV
LHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSSSISQQIAAEWFANGLYDEHLLFVRIQLKKRRDFMLKMLE
KYCCDIATWYEPVGGFYIWLHMNVPVSNRSLFDKALKEKILLNPGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAKLMK
K

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=28.343949044586, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=28.343949044586, Blast_Score=129, Evalue=7e-30,
Organism=Escherichia coli, GI1787710, Length=476, Percent_Identity=25.6302521008403, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1790797, Length=479, Percent_Identity=25.678496868476, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1788722, Length=319, Percent_Identity=24.1379310344828, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=359, Percent_Identity=21.7270194986072, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321929, Length=353, Percent_Identity=20.9631728045326, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356535, Length=397, Percent_Identity=21.1586901763224, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54719; Mature: 54719

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMERFVWKPNMSLATPLYKQIETYIKERIVNGKWTVGTKLPSQRDLAHIFGVNRSTIVMA
CCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHCHHHHHCCCCCEEEEE
FDELAAKGYIEGNGRKGTIVVNNNENASIYAPPPNWQSYVETGLHYPNLPAIQEINQAEF
EHHHHHCCEEECCCCEEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCHHHHHCCHHHC
YPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEPKGNFYLRKKIADYLKGHGV
CCHHEEECCCHHCHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHCCCCE
YVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGIPMDEN
EECCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEHHHHCCCEEEEECCCCC
GLHPSYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQD
CCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
LWFDKPISKPLKAYDKNGIVLHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGS
HHCCCCCCCHHHHHCCCCEEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHCEEECCCCC
SSISQQIAAEWFANGLYDEHLLFVRIQLKKRRDFMLKMLEKYCCDIATWYEPVGGFYIWL
HHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
HMNVPVSNRSLFDKALKEKILLNPGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAKLMK
EEECCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MMERFVWKPNMSLATPLYKQIETYIKERIVNGKWTVGTKLPSQRDLAHIFGVNRSTIVMA
CCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHCHHHHHCCCCCEEEEE
FDELAAKGYIEGNGRKGTIVVNNNENASIYAPPPNWQSYVETGLHYPNLPAIQEINQAEF
EHHHHHCCEEECCCCEEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCHHHHHCCHHHC
YPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEPKGNFYLRKKIADYLKGHGV
CCHHEEECCCHHCHHCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHCCCCE
YVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGIPMDEN
EECCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEHHHHCCCEEEEECCCCC
GLHPSYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQD
CCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
LWFDKPISKPLKAYDKNGIVLHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGS
HHCCCCCCCHHHHHCCCCEEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHCEEECCCCC
SSISQQIAAEWFANGLYDEHLLFVRIQLKKRRDFMLKMLEKYCCDIATWYEPVGGFYIWL
HHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
HMNVPVSNRSLFDKALKEKILLNPGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAKLMK
EEECCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]