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The map label for this gene is yplQ [C]

Identifier: 52143211

GI number: 52143211

Start: 2148254

End: 2148910

Strand: Reverse

Name: yplQ [C]

Synonym: BCZK2025

Alternate gene names: 52143211

Gene position: 2148910-2148254 (Counterclockwise)

Preceding gene: 52143208

Following gene: 52143219

Centisome position: 40.54

GC content: 36.23

Gene sequence:

>657_bases
ATGACTGAAAAAATGACACGAATGACACAATTTGTGAAAGAAGAAATTGCAAATGCAATTACACATGGTATCGGTGCCAT
TTTAAGCATCCCTGCCTTAATCATATTAATTATTCATGCCTCTAAGCATGGTACCGCATCTGCAGTAGTTGCATTTACGG
TTTATGGTGTAAGCATGTTCTTACTGTACTTGTTTTCGACATTGTTACATAGCATTCACCATCCAAAAGTAGAAAAATTA
TTTACTATACTAGATCACTCAGCCATTTATTTATTAATCGCTGGCACATATACTCCTTTTTTACTTATTACGCTTCGTGG
ACCATTAGGTTGGACGTTACTCGCAATTATATGGACACTAGCAATCGGGGGTATCATCTTCAAAATTTTCTTTGTACGAC
GCTTTATTAAGGCATCAACGCTATGTTATATCATAATGGGATGGCTCATAATCGTTGCTATTAAACCACTTTATGAAAAT
CTAACTGGACATGGTTTTTCACTACTTTTAGCAGGTGGAATTTTATATTCTGTCGGAGCTATATTCTTCCTTTGGGAAAA
GTTGCCGTTCAATCATGCCATTTGGCATCTTTTCGTATTAGGTGGTAGTGCAATGATGTTCTTCTGTGTACTCTTTTACG
TCTTACCTACAGCATAA

Upstream 100 bases:

>100_bases
AATATAATCAATTATACAAATTTCATTTTCTATTGCCCTTGTGTATGATATGGTAAGGGAAACGACATATTATTTTATAA
TAGTAGAAAGGATTGGCATT

Downstream 100 bases:

>100_bases
TAAAAAAGGTTTCAGCTTACTGTAAGCTGAAACCTTTTTTATTACTTATGTAACTGTGATGCGATAACTTCCTGTGTATG
CTTTGTTAATTCTTTAATAT

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVEKL
FTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYEN
LTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA

Sequences:

>Translated_218_residues
MTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVEKL
FTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYEN
LTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
>Mature_217_residues
TEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVEKLF
TILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYENL
TGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family

Homologues:

Organism=Homo sapiens, GI154759275, Length=223, Percent_Identity=30.4932735426009, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI52630445, Length=215, Percent_Identity=29.7674418604651, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI154759277, Length=246, Percent_Identity=28.0487804878049, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789266, Length=216, Percent_Identity=43.5185185185185, Blast_Score=181, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71996356, Length=213, Percent_Identity=31.924882629108, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24640324, Length=228, Percent_Identity=29.3859649122807, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HLY3_BACCE (P54176)

Other databases:

- EMBL:   X84058
- PIR:   S59967
- GO:   GO:0019835
- GO:   GO:0009405
- InterPro:   IPR004254
- InterPro:   IPR005744
- PANTHER:   PTHR20855
- PANTHER:   PTHR20855:SF3
- TIGRFAMs:   TIGR01065

Pfam domain/function: PF03006 HlyIII

EC number: NA

Molecular weight: Translated: 24320; Mature: 24189

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x152d89e0)-; HASH(0x17009cdc)-; HASH(0x15f1e37c)-; HASH(0x13addafc)-; HASH(0x169983d8)-; HASH(0x16c8bfa0)-; HASH(0x169e87cc)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTL
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
AIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTL
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
AIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855