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The map label for this gene is argE [H]

Identifier: 52143162

GI number: 52143162

Start: 2199597

End: 2200865

Strand: Direct

Name: argE [H]

Synonym: BCZK2076

Alternate gene names: 52143162

Gene position: 2199597-2200865 (Clockwise)

Preceding gene: 52143163

Following gene: 52143160

Centisome position: 41.49

GC content: 38.69

Gene sequence:

>1269_bases
ATGGAGCAATTAAAAAAACAAATTTGTGATTATATTGAGAGTCAAGAAGAAGAGAGCGTAAAATTTTTAAAACGATTAAT
TCAAGAAAAGAGCGTATCTGGTGATGAAAGTGGTGCACAGGCAATTGTGATTGAAAAATTGCGCGAGCTAGGTTTAGATC
TTGATATTTGGGAACCTTCATTTTCTAAAATGAAAGATCATCCTTATTTTGTATCACCACGTACAAGTTTTTCGGATAGC
CCGAACATTGTAGCAATCCTTAAAGGAAGCGGCGACGGGAAATCTATGATATTAAATGGACATATTGATGTCGTACCAGA
AGGAGATGTGGACCAGTGGGACCATCATCCCTATAGTGGTGAGAGAATAGGAAATCGTATATACGGCCGTGGAACAACGG
ATATGAAAGGTGGCAATGTCGCGCTAATGCTTGCGATGGAAGCAATTATTGAATCTCGTATTGAATTAAAAGGAGATATT
TATTTTCAAAGTGTAATAGAAGAAGAAAGCGGCGGAGCAGGAACATTAGCTACGATATTACGAGGATATAAAGCAGATGG
TGTCATTATTCCAGAGCCGACAAATATGAAGTTTTTCCCGAAACAACAAGGTTCTATGTGGTTTCGTCTACATGTGAAAG
GGAAAGCAGCGCATGGTGGAACACGTTATGAAGGAGTAAGTGCAATTGAAAAAAGTATGTTTGTTGTAGATCATTTGAGA
AAGCTGGAAGAAAAGAGAAATGATCGAATTACAGATCCGTTATTTAAAGGAATCCCGATTCCAATTCCAATTAATATTGG
AAAAATTGAAGGCGGAAGCTGGCCAAGTTCTGTTCCCGATTCGTTAATTTTAGAAGGAAGATGCGGTATTGCGCCGAATG
AGACTATAGAGGCAGCAAAAGAAGAGTTTGAGAATTGGATTACGGAATTAAATAATGTGGACAATTGGTTTGTTGAAAAT
CCTGTAGAAGTAGAATGGTTTGGAGCAAGATGGGTTCCAGGTGAACTGGAAGAAAATCATGAGTTAATGACAACGCTCGA
GCATAACTTTGTTGAAATCGAAGGGAACAAACCGATTATTGAAGCATCTCCGTGGGGGACTGATGGAGGCTTATTTACAC
AAATCGCAGGTGTACCAACGATAGTATTTGGCCCAGGGGAGACGAAAGTAGCGCATTATCCAAACGAATATATAGAAGTT
GATAAAATGATAGCTGCCGCAAAAATTATTGCATGTACATTACTAGATTGGTGTGAGGTGAAAAAATGA

Upstream 100 bases:

>100_bases
GATGAGCCCTTACACAGTGGAAGATATAAAGCAACATACAGAAGCAAATTTTAAAATTGGCTCTAACTTACTAGTAATTG
AATGAGGGGAGATGTAATAT

Downstream 100 bases:

>100_bases
AATACTATGAATCTTTTAGAGAACAGACGAATGGCTATACAGTAGAAGGTGTTTTGGACTATTTTAATAAACGTATTCGA
GTAGACCACTACACAGGAAA

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MEQLKKQICDYIESQEEESVKFLKRLIQEKSVSGDESGAQAIVIEKLRELGLDLDIWEPSFSKMKDHPYFVSPRTSFSDS
PNIVAILKGSGDGKSMILNGHIDVVPEGDVDQWDHHPYSGERIGNRIYGRGTTDMKGGNVALMLAMEAIIESRIELKGDI
YFQSVIEEESGGAGTLATILRGYKADGVIIPEPTNMKFFPKQQGSMWFRLHVKGKAAHGGTRYEGVSAIEKSMFVVDHLR
KLEEKRNDRITDPLFKGIPIPIPINIGKIEGGSWPSSVPDSLILEGRCGIAPNETIEAAKEEFENWITELNNVDNWFVEN
PVEVEWFGARWVPGELEENHELMTTLEHNFVEIEGNKPIIEASPWGTDGGLFTQIAGVPTIVFGPGETKVAHYPNEYIEV
DKMIAAAKIIACTLLDWCEVKK

Sequences:

>Translated_422_residues
MEQLKKQICDYIESQEEESVKFLKRLIQEKSVSGDESGAQAIVIEKLRELGLDLDIWEPSFSKMKDHPYFVSPRTSFSDS
PNIVAILKGSGDGKSMILNGHIDVVPEGDVDQWDHHPYSGERIGNRIYGRGTTDMKGGNVALMLAMEAIIESRIELKGDI
YFQSVIEEESGGAGTLATILRGYKADGVIIPEPTNMKFFPKQQGSMWFRLHVKGKAAHGGTRYEGVSAIEKSMFVVDHLR
KLEEKRNDRITDPLFKGIPIPIPINIGKIEGGSWPSSVPDSLILEGRCGIAPNETIEAAKEEFENWITELNNVDNWFVEN
PVEVEWFGARWVPGELEENHELMTTLEHNFVEIEGNKPIIEASPWGTDGGLFTQIAGVPTIVFGPGETKVAHYPNEYIEV
DKMIAAAKIIACTLLDWCEVKK
>Mature_422_residues
MEQLKKQICDYIESQEEESVKFLKRLIQEKSVSGDESGAQAIVIEKLRELGLDLDIWEPSFSKMKDHPYFVSPRTSFSDS
PNIVAILKGSGDGKSMILNGHIDVVPEGDVDQWDHHPYSGERIGNRIYGRGTTDMKGGNVALMLAMEAIIESRIELKGDI
YFQSVIEEESGGAGTLATILRGYKADGVIIPEPTNMKFFPKQQGSMWFRLHVKGKAAHGGTRYEGVSAIEKSMFVVDHLR
KLEEKRNDRITDPLFKGIPIPIPINIGKIEGGSWPSSVPDSLILEGRCGIAPNETIEAAKEEFENWITELNNVDNWFVEN
PVEVEWFGARWVPGELEENHELMTTLEHNFVEIEGNKPIIEASPWGTDGGLFTQIAGVPTIVFGPGETKVAHYPNEYIEV
DKMIAAAKIIACTLLDWCEVKK

Specific function: Unknown

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=306, Percent_Identity=24.1830065359477, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789236, Length=428, Percent_Identity=24.0654205607477, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1790395, Length=419, Percent_Identity=25.2983293556086, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788816, Length=404, Percent_Identity=23.5148514851485, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649206, Length=331, Percent_Identity=25.0755287009063, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24649202, Length=347, Percent_Identity=24.4956772334294, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649204, Length=347, Percent_Identity=24.4956772334294, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356353, Length=311, Percent_Identity=21.8649517684887, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24649210, Length=363, Percent_Identity=23.6914600550964, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 47101; Mature: 47101

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLKKQICDYIESQEEESVKFLKRLIQEKSVSGDESGAQAIVIEKLRELGLDLDIWEPS
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEECCCC
FSKMKDHPYFVSPRTSFSDSPNIVAILKGSGDGKSMILNGHIDVVPEGDVDQWDHHPYSG
HHHHCCCCEEECCCCCCCCCCCEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCCCCC
ERIGNRIYGRGTTDMKGGNVALMLAMEAIIESRIELKGDIYFQSVIEEESGGAGTLATIL
HHHCCEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHH
RGYKADGVIIPEPTNMKFFPKQQGSMWFRLHVKGKAAHGGTRYEGVSAIEKSMFVVDHLR
CCCCCCCEEECCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
KLEEKRNDRITDPLFKGIPIPIPINIGKIEGGSWPSSVPDSLILEGRCGIAPNETIEAAK
HHHHHHCCCCCCHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHH
EEFENWITELNNVDNWFVENPVEVEWFGARWVPGELEENHELMTTLEHNFVEIEGNKPII
HHHHHHHHHHCCCCCEECCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEE
EASPWGTDGGLFTQIAGVPTIVFGPGETKVAHYPNEYIEVDKMIAAAKIIACTLLDWCEV
ECCCCCCCCCHHHHHCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
KK
CC
>Mature Secondary Structure
MEQLKKQICDYIESQEEESVKFLKRLIQEKSVSGDESGAQAIVIEKLRELGLDLDIWEPS
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEECCCC
FSKMKDHPYFVSPRTSFSDSPNIVAILKGSGDGKSMILNGHIDVVPEGDVDQWDHHPYSG
HHHHCCCCEEECCCCCCCCCCCEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCCCCC
ERIGNRIYGRGTTDMKGGNVALMLAMEAIIESRIELKGDIYFQSVIEEESGGAGTLATIL
HHHCCEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHH
RGYKADGVIIPEPTNMKFFPKQQGSMWFRLHVKGKAAHGGTRYEGVSAIEKSMFVVDHLR
CCCCCCCEEECCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
KLEEKRNDRITDPLFKGIPIPIPINIGKIEGGSWPSSVPDSLILEGRCGIAPNETIEAAK
HHHHHHCCCCCCHHHCCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHHH
EEFENWITELNNVDNWFVENPVEVEWFGARWVPGELEENHELMTTLEHNFVEIEGNKPII
HHHHHHHHHHCCCCCEECCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCEEEEECCCCEE
EASPWGTDGGLFTQIAGVPTIVFGPGETKVAHYPNEYIEVDKMIAAAKIIACTLLDWCEV
ECCCCCCCCCHHHHHCCCCEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
KK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]