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The map label for this gene is entC [H]

Identifier: 52143110

GI number: 52143110

Start: 2251020

End: 2252219

Strand: Direct

Name: entC [H]

Synonym: BCZK2128

Alternate gene names: 52143110

Gene position: 2251020-2252219 (Clockwise)

Preceding gene: 52143111

Following gene: 52143109

Centisome position: 42.46

GC content: 38.17

Gene sequence:

>1200_bases
ATGAATGAATTTACGGCTGTAAAGGAACTGTCAGAAAAATTACTAGAAGATTATAAGACTGAATCTTCATTCTTTTTTGC
TTCACCAACCCGAACGATATTAGCAGAAGGAGAATTTACTACAGTAAAGCATCATGAAATTGAAAGCTTCCCAGAGCTTG
TGCAAGCAGTATTACGTAATGCAAAACAAGCCGGAAATCCGAATCCTATCGTTGTGGGGGCTTTGCCATTTGATCGTAGA
AAAGAAGTCCAACTTATCGTACCAGAATATAGCAGAATTTCTGAGCGTTTACAATTGGATACAACAAATCATCTTGAAAT
AAATAGGAACTTAACATTCGAAATGACGCCTGTGCCAGATCATGAAGTGTATATGAATGGTGTGAAGCAAGGAATTGAAA
AAATAAAGGACGGAGATTTAAAGAAAATCGTTCTATCTAGATCGTTAGATGTTAAATCTTCTGGAAAAATTGATAAGCAA
AAACTTCTTCGAGAATTAGCAGAGCATAATAAGCACGGTTATACATTTGCGGTGAAATTACCGAAAGATGAAAACGAGAA
TAGTAAGACGTTAATTGGAGCTAGTCCTGAATTACTCGTTTCACGTCATGGTATGCAAGTGATTTCTAATCCGTTAGCTG
GTTCAAGACCACGTAGTGATGATCCAGTAGAAGATAAAAGAAGAGCGGAGGAATTACTTTCTTCTCCAAAAGATTTGCAT
GAACATGCGGTAGTAGTGGAAGCAGTTGCTGCTGCGCTTGGCCCATACTGTCATACATTACATGTTCCGGAAAAACCATC
TGTTATTCATAGTGAAGCGATGTGGCATTTGTCTACTGAAGTGAAAGGTGAACTAAAGAATCCAAATACTAGTTCTTTAG
AATTAGCAATTGCTCTTCATCCTACGCCAGCAGTTTGCGGAACGCCGATGGAAGAAGCGAGAGAAGCTATTCAACAAATT
GAGCCATTTGACCGTGAGTTCTTTACAGGAATGTTAGGGTGGAGCGATTTAAATGGAGACGGTGAATGGATTGTTACAAT
TCGTTGTGCTGAAGTACAAGAAAATACACTCCGTTTATATGCAGGTGCTGGAGTTGTTGCTGAGTCAAAACCAGAAGATG
AATTAGCAGAAACAACAGCTAAGTTTCAAACAATGTTGAAAGCTTTAGGGTTAAATGATAGTTCACTTAATGAAAAGTAG

Upstream 100 bases:

>100_bases
TAGCTTCAGATAAAGCGAGTCATATTACAATGCACAATTTATGTGTCGATGGCGGAGCTACATTAGGAGTTTAATAAAAA
ATTTAGGGGGCTACTATACT

Downstream 100 bases:

>100_bases
GGGGCAGAAAGAATGTTAACAGGTTATACAAAATGGCCAAAAGAATTTGCCGATCGCTATCGAGAGGAAGGGTGTTGGCT
TGGGGAAACATTTGGCGGAG

Product: isochorismate synthase DhbC

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRR
KEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQ
KLLRELAEHNKHGYTFAVKLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
EHAVVVEAVAAALGPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQI
EPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETTAKFQTMLKALGLNDSSLNEK

Sequences:

>Translated_399_residues
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRR
KEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQ
KLLRELAEHNKHGYTFAVKLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
EHAVVVEAVAAALGPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQI
EPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETTAKFQTMLKALGLNDSSLNEK
>Mature_399_residues
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRNAKQAGNPNPIVVGALPFDRR
KEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPDHEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQ
KLLRELAEHNKHGYTFAVKLPKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
EHAVVVEAVAAALGPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALHPTPAVCGTPMEEAREAIQQI
EPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLYAGAGVVAESKPEDELAETTAKFQTMLKALGLNDSSLNEK

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=377, Percent_Identity=37.6657824933687, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI87082077, Length=275, Percent_Identity=29.8181818181818, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788114, Length=270, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787518, Length=277, Percent_Identity=28.158844765343, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320935, Length=280, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 44486; Mature: 44486

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHH
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPD
HHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCC
HEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQKLLRELAEHNKHGYTFAVKL
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
PKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
CCCCCCCCCEEECCCHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHH
EHAVVVEAVAAALGPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
HHHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHEECHHHCCCCCCCCCCCEEEEEEEC
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLY
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEE
AGAGVVAESKPEDELAETTAKFQTMLKALGLNDSSLNEK
ECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNEFTAVKELSEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEIESFPELVQAVLRN
CCCHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHH
AKQAGNPNPIVVGALPFDRRKEVQLIVPEYSRISERLQLDTTNHLEINRNLTFEMTPVPD
HHHCCCCCCEEEECCCCCCCCCEEEECCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCC
HEVYMNGVKQGIEKIKDGDLKKIVLSRSLDVKSSGKIDKQKLLRELAEHNKHGYTFAVKL
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
PKDENENSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLH
CCCCCCCCCEEECCCHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHH
EHAVVVEAVAAALGPYCHTLHVPEKPSVIHSEAMWHLSTEVKGELKNPNTSSLELAIALH
HHHHHHHHHHHHHCCHHEEECCCCCCCHHHHHHHHEECHHHCCCCCCCCCCCEEEEEEEC
PTPAVCGTPMEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVQENTLRLY
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEE
AGAGVVAESKPEDELAETTAKFQTMLKALGLNDSSLNEK
ECCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377 [H]