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The map label for this gene is ywfA [H]

Identifier: 52143054

GI number: 52143054

Start: 2310229

End: 2311431

Strand: Direct

Name: ywfA [H]

Synonym: BCZK2183

Alternate gene names: 52143054

Gene position: 2310229-2311431 (Clockwise)

Preceding gene: 52143056

Following gene: 52143052

Centisome position: 43.58

GC content: 32.67

Gene sequence:

>1203_bases
TTGTATATGGAGTTAAAGTCAATGATACGTATTTTGGCAATTGTAGCTTTTTTTGTTGGATTAGATTCATTATTAGTCGC
ACCTTTATTACCAGTAATTACAGAAACAATTAGTATCCCTGATGGGAGTGGAGGGTTATTAATTACTATTTATGCACTTT
GTTATGGAATAACTGCACCCGTATTTGGAATGATGTCTGATAGAGTTGGAAGGAAACGTATGATTATAATAGGGTTTATT
ATTTTTTCTATTTCTACATTTTGTACGGGATTAGCGAAGAATTTTGAAATTCTTTTATTATTTCGCGGTCTAACAGGTTT
ATCTGGTGCGATGATTATGCCAAGTATTTTTGCATTAGTAGGAGATAAAGTTACATATGAGTCAAGAGGAAAAGCGATGG
GAACGATTATGGGAGCAATGATAGGTTCAACAGTCATTGGAGTACCTATAGGCGCATTTTTATCTGAAATAGGAAATTGG
CAATGGACATTTTATAGTATAGGACTTTTAACTTTATTTCTGACATTACTAATTAATCACATATTAAGAAATGAAAAAGA
GAGAGATGATGTGCATGTTTCTTTAACGGAAACGGTGGATGCACCATTGAAAATGACTGTAGTAAATATATCAGTTTTAT
TTGCATTATTAGCAACGTTTTTATGGACAATTGGATTACATGGCATGTTTTCATACATAGGTGTTTATTATGAGAATAAT
TTTGGAATTTCCGTTGGTAAAATAGGTATAGTAATCTTTTTGGCAGGAGTTGGTAGTGTAGCTGGTAATATTTTAGGTGG
AAAGTTAGCTGATAAAATAGGAAAGAAGAATGTTATAGTCATTGCGAGTATTGTATCTTCAATTAGTGTAATGTTATTCT
CGCTTTCCACAGGAAATCTAGTAATTGCAATTATTGTACATATTATTTGGAGTTTATTTATTGGATTTGGACAAGCATCA
TTAACGGCACTAATTTCAGAATTAAAACCAGCTGTGCGAGGGACTGTAATGGCATTAAATAGCTCTGCCATGTATATTGG
GATGACTATTGCTTCTGGCGTAGCGTCACTTGCCATAAGTAATGGATTTCCGTTTTCTTCTTTAGGAACAATCTGTGCAA
TTGCTAGTTTACTTGTCCTTCCAATCATATTTGTTCTAGTTAAAGAAAAAGCATTATCTAATAAAAAGAAGATGACTATT
TAA

Upstream 100 bases:

>100_bases
ATTTATATAAATACTTCATATGTGAAATAAAATCTGGTACAGTGAAAATTGAAGAAGGGATAATAATAAATAATTATTTC
ATATATGAAATAAAGGGGAG

Downstream 100 bases:

>100_bases
TTAGTATGAAAGAAAACATGGGTTGATATTCTTCAAAGGATTTCAACTCATGTTTTCTTTCATATTATTTTATACTTTCA
TTACCTTTAATTGCGAAAGA

Product: multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MYMELKSMIRILAIVAFFVGLDSLLVAPLLPVITETISIPDGSGGLLITIYALCYGITAPVFGMMSDRVGRKRMIIIGFI
IFSISTFCTGLAKNFEILLLFRGLTGLSGAMIMPSIFALVGDKVTYESRGKAMGTIMGAMIGSTVIGVPIGAFLSEIGNW
QWTFYSIGLLTLFLTLLINHILRNEKERDDVHVSLTETVDAPLKMTVVNISVLFALLATFLWTIGLHGMFSYIGVYYENN
FGISVGKIGIVIFLAGVGSVAGNILGGKLADKIGKKNVIVIASIVSSISVMLFSLSTGNLVIAIIVHIIWSLFIGFGQAS
LTALISELKPAVRGTVMALNSSAMYIGMTIASGVASLAISNGFPFSSLGTICAIASLLVLPIIFVLVKEKALSNKKKMTI

Sequences:

>Translated_400_residues
MYMELKSMIRILAIVAFFVGLDSLLVAPLLPVITETISIPDGSGGLLITIYALCYGITAPVFGMMSDRVGRKRMIIIGFI
IFSISTFCTGLAKNFEILLLFRGLTGLSGAMIMPSIFALVGDKVTYESRGKAMGTIMGAMIGSTVIGVPIGAFLSEIGNW
QWTFYSIGLLTLFLTLLINHILRNEKERDDVHVSLTETVDAPLKMTVVNISVLFALLATFLWTIGLHGMFSYIGVYYENN
FGISVGKIGIVIFLAGVGSVAGNILGGKLADKIGKKNVIVIASIVSSISVMLFSLSTGNLVIAIIVHIIWSLFIGFGQAS
LTALISELKPAVRGTVMALNSSAMYIGMTIASGVASLAISNGFPFSSLGTICAIASLLVLPIIFVLVKEKALSNKKKMTI
>Mature_400_residues
MYMELKSMIRILAIVAFFVGLDSLLVAPLLPVITETISIPDGSGGLLITIYALCYGITAPVFGMMSDRVGRKRMIIIGFI
IFSISTFCTGLAKNFEILLLFRGLTGLSGAMIMPSIFALVGDKVTYESRGKAMGTIMGAMIGSTVIGVPIGAFLSEIGNW
QWTFYSIGLLTLFLTLLINHILRNEKERDDVHVSLTETVDAPLKMTVVNISVLFALLATFLWTIGLHGMFSYIGVYYENN
FGISVGKIGIVIFLAGVGSVAGNILGGKLADKIGKKNVIVIASIVSSISVMLFSLSTGNLVIAIIVHIIWSLFIGFGQAS
LTALISELKPAVRGTVMALNSSAMYIGMTIASGVASLAISNGFPFSSLGTICAIASLLVLPIIFVLVKEKALSNKKKMTI

Specific function: Unknown

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=289, Percent_Identity=27.681660899654, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787947, Length=276, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367379, Length=198, Percent_Identity=28.2828282828283, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081738, Length=340, Percent_Identity=27.0588235294118, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17864456, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24654039, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24654037, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24654041, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24654044, Length=186, Percent_Identity=26.3440860215054, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42674; Mature: 42674

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMELKSMIRILAIVAFFVGLDSLLVAPLLPVITETISIPDGSGGLLITIYALCYGITAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VFGMMSDRVGRKRMIIIGFIIFSISTFCTGLAKNFEILLLFRGLTGLSGAMIMPSIFALV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHH
GDKVTYESRGKAMGTIMGAMIGSTVIGVPIGAFLSEIGNWQWTFYSIGLLTLFLTLLINH
CCCCEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHH
ILRNEKERDDVHVSLTETVDAPLKMTVVNISVLFALLATFLWTIGLHGMFSYIGVYYENN
HHCCCCCCCCEEEEEHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
FGISVGKIGIVIFLAGVGSVAGNILGGKLADKIGKKNVIVIASIVSSISVMLFSLSTGNL
CCEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCH
VIAIIVHIIWSLFIGFGQASLTALISELKPAVRGTVMALNSSAMYIGMTIASGVASLAIS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHHHHHHC
NGFPFSSLGTICAIASLLVLPIIFVLVKEKALSNKKKMTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYMELKSMIRILAIVAFFVGLDSLLVAPLLPVITETISIPDGSGGLLITIYALCYGITAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VFGMMSDRVGRKRMIIIGFIIFSISTFCTGLAKNFEILLLFRGLTGLSGAMIMPSIFALV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHH
GDKVTYESRGKAMGTIMGAMIGSTVIGVPIGAFLSEIGNWQWTFYSIGLLTLFLTLLINH
CCCCEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHH
ILRNEKERDDVHVSLTETVDAPLKMTVVNISVLFALLATFLWTIGLHGMFSYIGVYYENN
HHCCCCCCCCEEEEEHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
FGISVGKIGIVIFLAGVGSVAGNILGGKLADKIGKKNVIVIASIVSSISVMLFSLSTGNL
CCEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCH
VIAIIVHIIWSLFIGFGQASLTALISELKPAVRGTVMALNSSAMYIGMTIASGVASLAIS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHHHHHHC
NGFPFSSLGTICAIASLLVLPIIFVLVKEKALSNKKKMTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]