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The map label for this gene is asd [H]

Identifier: 52143052

GI number: 52143052

Start: 2312503

End: 2313546

Strand: Direct

Name: asd [H]

Synonym: BCZK2185

Alternate gene names: 52143052

Gene position: 2312503-2313546 (Clockwise)

Preceding gene: 52143054

Following gene: 52143053

Centisome position: 43.62

GC content: 37.84

Gene sequence:

>1044_bases
ATGAGTGAAAAGGGCTATCATGTAGCTGTTGTTGGGGCTACGGGTGCAGTAGGTCAGAAAATTATTGAACTGTTAGAAAA
AGAAACAAAGTTTAATATAACTGAAGTTACGTTACTTTCGTCAAAAAGATCGGCTGGTAAGACAGTACAATTTAAAGGGC
GAGAGATCATTATACAAGAAGCAAAAATAAATAGCTTTGAAGGGGTAGATATTGCCTTTTTTAGCGCTGGAGGAGAAGTT
TCTAGACAATTTGTAAATCAAGCTGTCTCTAGCGGTGCAATCGTCATTGACAACACAAGTGAATACCGAATGGCACATGA
TGTACCGCTCGTTGTTCCGGAAGTGAATGCGCACACTTTAAAGGAACATAAAGGGATAATAGCAGTTCCGAATTGTTCAG
CATTACAGATGGTAACAGCTCTTCAGCCAATACGAAAAGTATTCGGATTAGAACGAATTATCGTTTCTACTTATCAGGCT
GTATCGGGTTCTGGTATTCATGCAATTCAAGAATTAAAAGAACAGGCTAAGTCAATACTTGCAGGTGAAGAAGTGGAGAG
TACTATATTACCAGCGAAAAAAGATAAAAAAAATTATCCAATTGCATTTAATGTACTTCCTCAAGTAGATATATTCACGG
ATAATGATTTCACCTTTGAAGAAGTAAAGATGATACAAGAAACGAAGAAAATTTTAGAAGACCCAAACTTGAAAATGGCA
GCTACTTGTGTGCGTGTTCCGGTTATATCAGGTCACTCAGAATCGGTTTATATAGAGCTTGAAAAAGAAGCAACTGTTGC
AGAAATTAAAGAAGTATTGTTTGATGCACCAGGTGTTATTTTGCAGGATAACCCTAGTGAACAGCTGTATCCAATGCCAT
TATACGCAGAAGGGAAAATAGATACATTTGTCGGTAGAATTAGAAAAGATCCTGATACACCAAACGGATTCCATCTTTGG
ATCGTTTCCGATAATTTATTAAAAGGTGCGGCGTGGAACTCGGTGCAAATTGCAGAAACGATGGTGGAAGAGGGAATCAT
TTAG

Upstream 100 bases:

>100_bases
GTGAATGATTATATCACGTATTTCAATTTTCCAAATGATTAAATTCCTTATAAAATGAAATTGTAGAAATATTTATTCAT
TTAATATTGGAGGAGAAAAG

Downstream 100 bases:

>100_bases
TATTAAGGAAACTAGGGAACTGTTAAAGATTACAGTTTCCTAGTTTTTATTTTATAACTGTTCGCTTTATTCCAGCCGTA
TTTAATTTGAAAGACAGTAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGREIIIQEAKINSFEGVDIAFFSAGGEV
SRQFVNQAVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTLKEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQA
VSGSGIHAIQELKEQAKSILAGEEVESTILPAKKDKKNYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKIDTFVGRIRKDPDTPNGFHLW
IVSDNLLKGAAWNSVQIAETMVEEGII

Sequences:

>Translated_347_residues
MSEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGREIIIQEAKINSFEGVDIAFFSAGGEV
SRQFVNQAVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTLKEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQA
VSGSGIHAIQELKEQAKSILAGEEVESTILPAKKDKKNYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKIDTFVGRIRKDPDTPNGFHLW
IVSDNLLKGAAWNSVQIAETMVEEGII
>Mature_346_residues
SEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGREIIIQEAKINSFEGVDIAFFSAGGEVS
RQFVNQAVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTLKEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQAV
SGSGIHAIQELKEQAKSILAGEEVESTILPAKKDKKNYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMAA
TCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKIDTFVGRIRKDPDTPNGFHLWI
VSDNLLKGAAWNSVQIAETMVEEGII

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=348, Percent_Identity=33.6206896551724, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=25.4847645429363, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=399, Percent_Identity=28.3208020050125, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38123; Mature: 37992

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGREIIIQE
CCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCEEEEEE
AKINSFEGVDIAFFSAGGEVSRQFVNQAVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTL
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEECCCCEEEECCCEEEEECCCCHHH
KEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQAVSGSGIHAIQELKEQAKSIL
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGEEVESTILPAKKDKKNYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
CCCHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEE
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKI
EEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCEECCCEEECCCH
DTFVGRIRKDPDTPNGFHLWIVSDNLLKGAAWNSVQIAETMVEEGII
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGREIIIQE
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCEEEEEE
AKINSFEGVDIAFFSAGGEVSRQFVNQAVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTL
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEECCCCEEEECCCEEEEECCCCHHH
KEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQAVSGSGIHAIQELKEQAKSIL
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGEEVESTILPAKKDKKNYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
CCCHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEE
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKI
EEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCEECCCEEECCCH
DTFVGRIRKDPDTPNGFHLWIVSDNLLKGAAWNSVQIAETMVEEGII
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]