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The map label for this gene is phnW [H]

Identifier: 52143021

GI number: 52143021

Start: 2345079

End: 2346662

Strand: Direct

Name: phnW [H]

Synonym: BCZK2217

Alternate gene names: 52143021

Gene position: 2345079-2346662 (Clockwise)

Preceding gene: 52143022

Following gene: 52143020

Centisome position: 44.24

GC content: 34.15

Gene sequence:

>1584_bases
ATGGGGTTAATTTATAAAGTTGCTGATCAAGTTTGGGAATTTGAAAGTATACATAAATTGAATTATAAAACATTTGTAGA
AGAAATTCCGCAACATGAAGAAACGAAAGATCGTGTTCGTATAGATCGTTTTCATGAAGAAAATACATATTTAATTTGTT
TAGATGACGATAAGTTAGTAGGTATGGTTGCGTTGCGAGGAAAACGACCATTCTCGTTAGATTATAAAATTTCAAATCTA
GATTTTTATTTGCAAGAACATGGAGAAAACGTATATGAAATTCGTTTACTTTCAGTAGAAAGTGAATATCGAAATGGAAG
AGCGTTATTAGGTTTAATTCGCTTTTTACATCGTTATTTGCTTCTAAATGGATATGAATTGGCACTCATTTCTGCAACAA
CACGTGAACTACCTTTATATGAGCAAATGGGATTCAAATCTTTCCATTCGTTAGTTGGTACAGAAGCAGCAGCATTCCAG
CCAATGTATGTTACCCCTGCTATGTTTGAAGCGTCGAGTGTTGGGGGAATTATGACGAAAGAGTATACGTTTTTACCCGG
CCCAGTAGATATTGAAGAGAATGTTCGAAAGGCATTTTCTACTAAGCCTATTTCACACCGTTCTAAGTCATTTCAAGTGA
CGATGGATAATGTAAAGAAACGATTACTTCAAATGACAAAAGCAAAACGTGTGCAAATCATGTTAGGAACAGGGACATTA
GCGAATGATGCCATTGCTTTACAGTTACGTTCTTTAAAAGGAAAGGGGCTCGTATTAACAAATGGGGAATTTGGTAATAG
ATTAGTCGAGCATGCAACGCGCGCGCAATTACATTTTGATACGTATAAAAAAGAAATGGGGGAACCATTTCTTTATACAG
AATTAGAAAAAGTAATGGAAAGTGGAATTTATGAATGGCTTTGGTTTGTTCACCATGAAACATCTACCGGAATGTTAAAT
GATTTAGACGAGCTAAATGCTCTAAGTAACAAGTATCAACTGAAACTATGTGTAGATTGTATCAGTTCGATTGGAGCAAT
ACCGATAGATTTAAAGGATATATATTTTGCAAGCGGTGTTAGTGGAAAAGCGATTAAATCATATACAGGATTATCTTTTG
TTTTTCATAACCATATTGTAAAAATAAATGAAGCAGTACCGGCCTATATGGACATTGGTATGTACGAAGAAAATGAAAGT
ATTCCATATTCTCATTCATGGAATTTAATTTATGCTTTGCAAGAAGCATTGAAAAGCTTTGAAGATGAAACAGCATTTGA
AAAAATAAAAGAGACCTATGCGTATATTGAACAAGCTATTACTACTATGGGGTTAAAACTTGTTTCACCGAAAGAACATG
CCGCACCAATTATACTTACGATTCAATTAAGCGAAGGCCAGTCCTCTAAAACGATAGGTGATGAGTTAGCATTACAAGGA
TATATTGCCCATTATGAATCAGCGTATTTACAAAAGAATAACTGGATCCAAATCTCATGCCTAAATCATTACAAAGAACG
TGATATGAAAAGGATGTTGAATTGTTTACAAATGTGTGTATTACAGAGTGAGGTACATATATAA

Upstream 100 bases:

>100_bases
GTACTTATTTTATATGTAAATCGCGAATGAAATAAACATTTAATAAGTGGGGTTAATCTCCACTTATCATTTTTTATTAA
ATTGATAAAGGAGATAGGGC

Downstream 100 bases:

>100_bases
AGACTTTTTCTTAATATAGATGGTTTCGTATAAAGGAGTTGCTACATACGAAAACTTAGGAATAGAACATTGGAAGGGGT
GTTAGTATGATAACTAAAAA

Product: serine-pyruvate aminotransferase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MGLIYKVADQVWEFESIHKLNYKTFVEEIPQHEETKDRVRIDRFHEENTYLICLDDDKLVGMVALRGKRPFSLDYKISNL
DFYLQEHGENVYEIRLLSVESEYRNGRALLGLIRFLHRYLLLNGYELALISATTRELPLYEQMGFKSFHSLVGTEAAAFQ
PMYVTPAMFEASSVGGIMTKEYTFLPGPVDIEENVRKAFSTKPISHRSKSFQVTMDNVKKRLLQMTKAKRVQIMLGTGTL
ANDAIALQLRSLKGKGLVLTNGEFGNRLVEHATRAQLHFDTYKKEMGEPFLYTELEKVMESGIYEWLWFVHHETSTGMLN
DLDELNALSNKYQLKLCVDCISSIGAIPIDLKDIYFASGVSGKAIKSYTGLSFVFHNHIVKINEAVPAYMDIGMYEENES
IPYSHSWNLIYALQEALKSFEDETAFEKIKETYAYIEQAITTMGLKLVSPKEHAAPIILTIQLSEGQSSKTIGDELALQG
YIAHYESAYLQKNNWIQISCLNHYKERDMKRMLNCLQMCVLQSEVHI

Sequences:

>Translated_527_residues
MGLIYKVADQVWEFESIHKLNYKTFVEEIPQHEETKDRVRIDRFHEENTYLICLDDDKLVGMVALRGKRPFSLDYKISNL
DFYLQEHGENVYEIRLLSVESEYRNGRALLGLIRFLHRYLLLNGYELALISATTRELPLYEQMGFKSFHSLVGTEAAAFQ
PMYVTPAMFEASSVGGIMTKEYTFLPGPVDIEENVRKAFSTKPISHRSKSFQVTMDNVKKRLLQMTKAKRVQIMLGTGTL
ANDAIALQLRSLKGKGLVLTNGEFGNRLVEHATRAQLHFDTYKKEMGEPFLYTELEKVMESGIYEWLWFVHHETSTGMLN
DLDELNALSNKYQLKLCVDCISSIGAIPIDLKDIYFASGVSGKAIKSYTGLSFVFHNHIVKINEAVPAYMDIGMYEENES
IPYSHSWNLIYALQEALKSFEDETAFEKIKETYAYIEQAITTMGLKLVSPKEHAAPIILTIQLSEGQSSKTIGDELALQG
YIAHYESAYLQKNNWIQISCLNHYKERDMKRMLNCLQMCVLQSEVHI
>Mature_526_residues
GLIYKVADQVWEFESIHKLNYKTFVEEIPQHEETKDRVRIDRFHEENTYLICLDDDKLVGMVALRGKRPFSLDYKISNLD
FYLQEHGENVYEIRLLSVESEYRNGRALLGLIRFLHRYLLLNGYELALISATTRELPLYEQMGFKSFHSLVGTEAAAFQP
MYVTPAMFEASSVGGIMTKEYTFLPGPVDIEENVRKAFSTKPISHRSKSFQVTMDNVKKRLLQMTKAKRVQIMLGTGTLA
NDAIALQLRSLKGKGLVLTNGEFGNRLVEHATRAQLHFDTYKKEMGEPFLYTELEKVMESGIYEWLWFVHHETSTGMLND
LDELNALSNKYQLKLCVDCISSIGAIPIDLKDIYFASGVSGKAIKSYTGLSFVFHNHIVKINEAVPAYMDIGMYEENESI
PYSHSWNLIYALQEALKSFEDETAFEKIKETYAYIEQAITTMGLKLVSPKEHAAPIILTIQLSEGQSSKTIGDELALQGY
IAHYESAYLQKNNWIQISCLNHYKERDMKRMLNCLQMCVLQSEVHI

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=308, Percent_Identity=24.025974025974, Blast_Score=77, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 60448; Mature: 60317

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLIYKVADQVWEFESIHKLNYKTFVEEIPQHEETKDRVRIDRFHEENTYLICLDDDKLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECCCEEEEEECCCCEE
GMVALRGKRPFSLDYKISNLDFYLQEHGENVYEIRLLSVESEYRNGRALLGLIRFLHRYL
EEEEECCCCCCEEEEEECCCEEEEHHCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
LLNGYELALISATTRELPLYEQMGFKSFHSLVGTEAAAFQPMYVTPAMFEASSVGGIMTK
HHCCCEEEEEEECCCCCCCHHHHCHHHHHHHHCCHHHHCCCEEECHHHHCCCCCCCEEEC
EYTFLPGPVDIEENVRKAFSTKPISHRSKSFQVTMDNVKKRLLQMTKAKRVQIMLGTGTL
CEEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEEECCCC
ANDAIALQLRSLKGKGLVLTNGEFGNRLVEHATRAQLHFDTYKKEMGEPFLYTELEKVME
CCCEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SGIYEWLWFVHHETSTGMLNDLDELNALSNKYQLKLCVDCISSIGAIPIDLKDIYFASGV
CCHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHEECCC
SGKAIKSYTGLSFVFHNHIVKINEAVPAYMDIGMYEENESIPYSHSWNLIYALQEALKSF
CCCHHHHHCCEEEEECCCEEEECCCCCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
EDETAFEKIKETYAYIEQAITTMGLKLVSPKEHAAPIILTIQLSEGQSSKTIGDELALQG
CHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
YIAHYESAYLQKNNWIQISCLNHYKERDMKRMLNCLQMCVLQSEVHI
HHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLIYKVADQVWEFESIHKLNYKTFVEEIPQHEETKDRVRIDRFHEENTYLICLDDDKLV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECCCEEEEEECCCCEE
GMVALRGKRPFSLDYKISNLDFYLQEHGENVYEIRLLSVESEYRNGRALLGLIRFLHRYL
EEEEECCCCCCEEEEEECCCEEEEHHCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHH
LLNGYELALISATTRELPLYEQMGFKSFHSLVGTEAAAFQPMYVTPAMFEASSVGGIMTK
HHCCCEEEEEEECCCCCCCHHHHCHHHHHHHHCCHHHHCCCEEECHHHHCCCCCCCEEEC
EYTFLPGPVDIEENVRKAFSTKPISHRSKSFQVTMDNVKKRLLQMTKAKRVQIMLGTGTL
CEEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHCCEEEEEEECCCC
ANDAIALQLRSLKGKGLVLTNGEFGNRLVEHATRAQLHFDTYKKEMGEPFLYTELEKVME
CCCEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SGIYEWLWFVHHETSTGMLNDLDELNALSNKYQLKLCVDCISSIGAIPIDLKDIYFASGV
CCHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHHEECCC
SGKAIKSYTGLSFVFHNHIVKINEAVPAYMDIGMYEENESIPYSHSWNLIYALQEALKSF
CCCHHHHHCCEEEEECCCEEEECCCCCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
EDETAFEKIKETYAYIEQAITTMGLKLVSPKEHAAPIILTIQLSEGQSSKTIGDELALQG
CHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCEEEEEEECCCCCCCCCHHHHHHHH
YIAHYESAYLQKNNWIQISCLNHYKERDMKRMLNCLQMCVLQSEVHI
HHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA