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The map label for this gene is dadA [H]

Identifier: 52142787

GI number: 52142787

Start: 2586446

End: 2587561

Strand: Reverse

Name: dadA [H]

Synonym: BCZK2454

Alternate gene names: 52142787

Gene position: 2587561-2586446 (Counterclockwise)

Preceding gene: 52142785

Following gene: 52142786

Centisome position: 48.81

GC content: 38.8

Gene sequence:

>1116_bases
ATGAAATTGTATATTGTAGTTGGAGCTGGTATTTTAGGAGCGTCTACTGCTTACCATCTTGCTAAAGCTGGCGCAAACGT
TACTATCGTGGATCGTCAACAATTAGGTCAAGCAACAGATGCAGCAGCTGGTATTGTTTGCCCATGGCTTTCACAACGTC
GTAATAAAGCATGGTATAAAATCGTTAAAGGCGGTGCACGTTACTATTCTTCATTAATTCAGCAATTAGAAGAAGATGGT
GAAACGGATACAGGTTATAACCGTGTAGGTGCAATTAGTTTACATACTGACGAGAAAAAACTAGATCAAATGGAAGAGCG
AGCATATAAACGTCGTGAAGATGCTCCAGAGATTGGTGAAATTACACGTTTATCAGCTGAAGAAACGAAAAAATTATTCC
CAGCATTATCAGAAGAATATAGTTCTGTTCATATTAGTGGTGCTGCACGAGTAAATGGAAGATTATTACGCAACGCATTA
ATAAGCGCTGCGAAAAAACATGGTGCAACTTTTATAAAAGGCGATGCAGTATTAGTCCGTGAAGGTAATCATATTACGGG
TGTTAAAGTAAACGATGAAACAATTTTAGCAGAGAAGGTTATTGTAACAGCAGGTGCATGGGCGAACGAAATCTTAAACC
CATTAGGAATTAATTTTTTAGTTACGTTCCAAAAAGGACAAATTGTTCACCTGCAAATGGAAAATACAGCAACAGAAAAT
ATGCCAGTTGTCATGCCGCCAAATGATCAATACATTTTAACATTTGACAATGGCCATGTCGTAATTGGTGCAACACATGA
GAATGAAACTGGTTTCGATCAACGTGTAACGGCTGGTGGTTTACATGAAGTATTCCATAAAGCAATAACAGTTGCACCTG
GCTTAGAAAATGCTACTATGCTTGAAACAAGAGTTGGATTCAGACCATTCACGCCAGGATTCTTACCTGTTATTGGACCA
CTCCCTAACTTTGAAGGCATTCTCGTTGCGAACGGATTAGGTGCTTCAGGTTTAACTGCAGGTCCATATTTAGGTTCAGA
ACTTGCTAAATTAGCGCTAGGACAACCAATTGAGTTAGATTTAAATGATTATGACGTTGCTGGCGCAATTGAATAA

Upstream 100 bases:

>100_bases
CAATTAATTGAGCTTAGCACATTGTAAAAAGGATTCCTTTCAGTATACTAAAGTATGTTCTTATATTTAAATAATTAGCA
AAAGAGAAAAGGTGTTTGAA

Downstream 100 bases:

>100_bases
CATCGGGTATGAAAAAAATACGCTAAGCAAATTCGATAGGAAATAAGCAGTTTTTTCTCCGTTAAGAGTAAGACTGTTTA
TGAAAAATAAAATTCTTTAA

Product: D-amino acid dehydrogenase small subunit

Products: 2-oxo acid; NH3; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKLYIVVGAGILGASTAYHLAKAGANVTIVDRQQLGQATDAAAGIVCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDG
ETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGEITRLSAEETKKLFPALSEEYSSVHISGAARVNGRLLRNAL
ISAAKKHGATFIKGDAVLVREGNHITGVKVNDETILAEKVIVTAGAWANEILNPLGINFLVTFQKGQIVHLQMENTATEN
MPVVMPPNDQYILTFDNGHVVIGATHENETGFDQRVTAGGLHEVFHKAITVAPGLENATMLETRVGFRPFTPGFLPVIGP
LPNFEGILVANGLGASGLTAGPYLGSELAKLALGQPIELDLNDYDVAGAIE

Sequences:

>Translated_371_residues
MKLYIVVGAGILGASTAYHLAKAGANVTIVDRQQLGQATDAAAGIVCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDG
ETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGEITRLSAEETKKLFPALSEEYSSVHISGAARVNGRLLRNAL
ISAAKKHGATFIKGDAVLVREGNHITGVKVNDETILAEKVIVTAGAWANEILNPLGINFLVTFQKGQIVHLQMENTATEN
MPVVMPPNDQYILTFDNGHVVIGATHENETGFDQRVTAGGLHEVFHKAITVAPGLENATMLETRVGFRPFTPGFLPVIGP
LPNFEGILVANGLGASGLTAGPYLGSELAKLALGQPIELDLNDYDVAGAIE
>Mature_371_residues
MKLYIVVGAGILGASTAYHLAKAGANVTIVDRQQLGQATDAAAGIVCPWLSQRRNKAWYKIVKGGARYYSSLIQQLEEDG
ETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGEITRLSAEETKKLFPALSEEYSSVHISGAARVNGRLLRNAL
ISAAKKHGATFIKGDAVLVREGNHITGVKVNDETILAEKVIVTAGAWANEILNPLGINFLVTFQKGQIVHLQMENTATEN
MPVVMPPNDQYILTFDNGHVVIGATHENETGFDQRVTAGGLHEVFHKAITVAPGLENATMLETRVGFRPFTPGFLPVIGP
LPNFEGILVANGLGASGLTAGPYLGSELAKLALGQPIELDLNDYDVAGAIE

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=390, Percent_Identity=26.4102564102564, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI21361378, Length=390, Percent_Identity=26.4102564102564, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI24797151, Length=400, Percent_Identity=24.25, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994045, Length=389, Percent_Identity=22.6221079691517, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20130091, Length=385, Percent_Identity=27.012987012987, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.4.99.1

Molecular weight: Translated: 40010; Mature: 40010

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYIVVGAGILGASTAYHLAKAGANVTIVDRQQLGQATDAAAGIVCPWLSQRRNKAWYK
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHCCCCEECCHHHHHCCHHHHH
IVKGGARYYSSLIQQLEEDGETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGE
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHH
ITRLSAEETKKLFPALSEEYSSVHISGAARVNGRLLRNALISAAKKHGATFIKGDAVLVR
HHHCCHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEE
EGNHITGVKVNDETILAEKVIVTAGAWANEILNPLGINFLVTFQKGQIVHLQMENTATEN
CCCEEEEEEECCCEEEEEEEEEECCCCHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
MPVVMPPNDQYILTFDNGHVVIGATHENETGFDQRVTAGGLHEVFHKAITVAPGLENATM
CCEEECCCCCEEEEECCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHEEECCCCCCCEE
LETRVGFRPFTPGFLPVIGPLPNFEGILVANGLGASGLTAGPYLGSELAKLALGQPIELD
EHHHCCCCCCCCCCCHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEC
LNDYDVAGAIE
CCCCCCCCCCC
>Mature Secondary Structure
MKLYIVVGAGILGASTAYHLAKAGANVTIVDRQQLGQATDAAAGIVCPWLSQRRNKAWYK
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHCCCHHHCCCCEECCHHHHHCCHHHHH
IVKGGARYYSSLIQQLEEDGETDTGYNRVGAISLHTDEKKLDQMEERAYKRREDAPEIGE
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHH
ITRLSAEETKKLFPALSEEYSSVHISGAARVNGRLLRNALISAAKKHGATFIKGDAVLVR
HHHCCHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEE
EGNHITGVKVNDETILAEKVIVTAGAWANEILNPLGINFLVTFQKGQIVHLQMENTATEN
CCCEEEEEEECCCEEEEEEEEEECCCCHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
MPVVMPPNDQYILTFDNGHVVIGATHENETGFDQRVTAGGLHEVFHKAITVAPGLENATM
CCEEECCCCCEEEEECCCEEEEEEECCCCCCCCHHCCCCHHHHHHHHHEEECCCCCCCEE
LETRVGFRPFTPGFLPVIGPLPNFEGILVANGLGASGLTAGPYLGSELAKLALGQPIELD
EHHHCCCCCCCCCCCHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEC
LNDYDVAGAIE
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-amino acid; H2O; acceptor

Specific reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]