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The map label for this gene is ntpA [C]

Identifier: 52142786

GI number: 52142786

Start: 2585805

End: 2586242

Strand: Reverse

Name: ntpA [C]

Synonym: BCZK2453

Alternate gene names: 52142786

Gene position: 2586242-2585805 (Counterclockwise)

Preceding gene: 52142787

Following gene: 52142790

Centisome position: 48.79

GC content: 34.02

Gene sequence:

>438_bases
ATGAGAGCACCATATCAAGTATTAATATTCCCTTATATAAAAACTGACGATTCTATTCAATATGCGATTTTTAACCGAAG
TGATTATGGTTATTGGCAAGGAATAGCTGGTGGTGGAGAAGATGGTGAGATTCCTATTGAATCAGCAAAACGGGAAGCGT
TTGAAGAAGCTGGTATTACAAGAGATTGTCCATATATACAATTAGATTCTGTGTCTTCACTACCAGTAGAGGATGTAGTT
GGAGGATTCCTTTGGGGAGATGAGGTTTATGTAATAAAAGAGTTTTCTTTTGGAGTTAAAGTACCTAACAAAAATATCTC
ATTATCTAAAGAACACTTACATTATAAATGGTTATGCTTTGAGGAGGCAGTAAAGTTTTTGAAATGGGATAGCAACAAAA
CAGCATTGTGGGAATTAAACAAAAGACTATTAAAATAG

Upstream 100 bases:

>100_bases
TAAAGAGCCGACACCATAAACTTGCATTATTAATGTAGAATTGTGATGTTTGCTCTTTATTTCTATTTATTTAAAGCTTT
TTTGGAGAGGAGGTTAAGTA

Downstream 100 bases:

>100_bases
TAAAAGTATTAGCAAAGACGTTAGTGGAACAAGAATTGAACAATTAAAAAACTTGCTATTCTTCATATATAGCAAGTTTT
TTTCTATACAGTTGCCTCTG

Product: dATP pyrophosphohydrolase

Products: dAMP; pyrophosphate [C]

Alternate protein names: MutT/Nudix Family Protein; NUDIX Family Hydrolase; DATP Pyrophosphohydrolase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRAPYQVLIFPYIKTDDSIQYAIFNRSDYGYWQGIAGGGEDGEIPIESAKREAFEEAGITRDCPYIQLDSVSSLPVEDVV
GGFLWGDEVYVIKEFSFGVKVPNKNISLSKEHLHYKWLCFEEAVKFLKWDSNKTALWELNKRLLK

Sequences:

>Translated_145_residues
MRAPYQVLIFPYIKTDDSIQYAIFNRSDYGYWQGIAGGGEDGEIPIESAKREAFEEAGITRDCPYIQLDSVSSLPVEDVV
GGFLWGDEVYVIKEFSFGVKVPNKNISLSKEHLHYKWLCFEEAVKFLKWDSNKTALWELNKRLLK
>Mature_145_residues
MRAPYQVLIFPYIKTDDSIQYAIFNRSDYGYWQGIAGGGEDGEIPIESAKREAFEEAGITRDCPYIQLDSVSSLPVEDVV
GGFLWGDEVYVIKEFSFGVKVPNKNISLSKEHLHYKWLCFEEAVKFLKWDSNKTALWELNKRLLK

Specific function: Hydrolysis Of Nucleoside Triphosphates With A Preference For Datp. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 16707; Mature: 16707

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAPYQVLIFPYIKTDDSIQYAIFNRSDYGYWQGIAGGGEDGEIPIESAKREAFEEAGIT
CCCCEEEEEEEEEECCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
RDCPYIQLDSVSSLPVEDVVGGFLWGDEVYVIKEFSFGVKVPNKNISLSKEHLHYKWLCF
CCCCEEEECCCCCCCHHHHHCCEEECCEEEEEEEECCCEECCCCCCCCCHHHCEEEEEEH
EEAVKFLKWDSNKTALWELNKRLLK
HHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MRAPYQVLIFPYIKTDDSIQYAIFNRSDYGYWQGIAGGGEDGEIPIESAKREAFEEAGIT
CCCCEEEEEEEEEECCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCC
RDCPYIQLDSVSSLPVEDVVGGFLWGDEVYVIKEFSFGVKVPNKNISLSKEHLHYKWLCF
CCCCEEEECCCCCCCHHHHHCCEEECCEEEEEEEECCCEECCCCCCCCCHHHCEEEEEEH
EEAVKFLKWDSNKTALWELNKRLLK
HHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxy-ATP; H2O [C]

Specific reaction: deoxy-ATP + H2O = dAMP + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA