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The map label for this gene is bcrC [H]

Identifier: 52142778

GI number: 52142778

Start: 2595122

End: 2595721

Strand: Reverse

Name: bcrC [H]

Synonym: BCZK2462

Alternate gene names: 52142778

Gene position: 2595721-2595122 (Counterclockwise)

Preceding gene: 52142777

Following gene: 52142780

Centisome position: 48.97

GC content: 33.0

Gene sequence:

>600_bases
ATGTCTTTTTCTCAATTCAATATTGATATTTTTCGAGCCATTAATGATTTAGGTAAACAATATTCATTCCTAAACCCAGC
CATAGTATTTTTGGCAGAATATATGGTATATATGTTTGCTTTAATTATTTTAGCTTATTGGTTTACTAGGTCCAGAAAAA
GTAGAATGATGGTTATTCAAGCGATGGTTGCTTTTGTAATTGCTGAGGTGATTGGAAAATTAGCAGGGAAATTCCATCTG
AATTATCAACCGTTTGCAGTATTGCCTCATGTTAATAAACTTGTCGACCATGCTGTAGATAATTCATTTCCTAGTGACCA
TACAATTCTCTTTTTTTCGATTTGTTTTTCGTTTTGGCTTGTTCGTAAAAAAACTGGATGGTTATGGCTTATACTTGCAT
TTTGTGTAGCGATCTCACGTATTTGGGTAGGGGTTCATTATCCTCTTGATGTTGCAGTAGGGGCTTTAATAGGATGTATT
TCAGCGGTATTTTCGCATTGGTTAGTACCGAAATTATCTTTTATTAGGCAATTACTTACTCAATATGAAAGAGTAGAGAA
ACATGTTTTACTATTCAAAAACAAATCAAAAGGATTGTGA

Upstream 100 bases:

>100_bases
TGAAGTTTTTATTTCTAGATGAGTACAATAACCAAAACTATTCATGTAATGAAAGTATATGGCATTCAGTAAAACACCTT
ACTAAAAGGAGAGATTTAAA

Downstream 100 bases:

>100_bases
GTACAATCCTTTATCATCCTCATTACTATTCTTCACAAGCTGAATGGGCCGAGATATCAATACACTTATTTACATCCAAG
AAGATGAAAAGGAATAGGTA

Product: bacitracin transport permease, PAP2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSFSQFNIDIFRAINDLGKQYSFLNPAIVFLAEYMVYMFALIILAYWFTRSRKSRMMVIQAMVAFVIAEVIGKLAGKFHL
NYQPFAVLPHVNKLVDHAVDNSFPSDHTILFFSICFSFWLVRKKTGWLWLILAFCVAISRIWVGVHYPLDVAVGALIGCI
SAVFSHWLVPKLSFIRQLLTQYERVEKHVLLFKNKSKGL

Sequences:

>Translated_199_residues
MSFSQFNIDIFRAINDLGKQYSFLNPAIVFLAEYMVYMFALIILAYWFTRSRKSRMMVIQAMVAFVIAEVIGKLAGKFHL
NYQPFAVLPHVNKLVDHAVDNSFPSDHTILFFSICFSFWLVRKKTGWLWLILAFCVAISRIWVGVHYPLDVAVGALIGCI
SAVFSHWLVPKLSFIRQLLTQYERVEKHVLLFKNKSKGL
>Mature_198_residues
SFSQFNIDIFRAINDLGKQYSFLNPAIVFLAEYMVYMFALIILAYWFTRSRKSRMMVIQAMVAFVIAEVIGKLAGKFHLN
YQPFAVLPHVNKLVDHAVDNSFPSDHTILFFSICFSFWLVRKKTGWLWLILAFCVAISRIWVGVHYPLDVAVGALIGCIS
AVFSHWLVPKLSFIRQLLTQYERVEKHVLLFKNKSKGL

Specific function: Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0671

COG function: function code I; Membrane-associated phospholipid phosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BcrC/YbjG family [H]

Homologues:

Organism=Escherichia coli, GI1787064, Length=165, Percent_Identity=30.9090909090909, Blast_Score=74, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016118
- InterPro:   IPR000326 [H]

Pfam domain/function: PF01569 PAP2 [H]

EC number: NA

Molecular weight: Translated: 23002; Mature: 22871

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSQFNIDIFRAINDLGKQYSFLNPAIVFLAEYMVYMFALIILAYWFTRSRKSRMMVIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
AMVAFVIAEVIGKLAGKFHLNYQPFAVLPHVNKLVDHAVDNSFPSDHTILFFSICFSFWL
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VRKKTGWLWLILAFCVAISRIWVGVHYPLDVAVGALIGCISAVFSHWLVPKLSFIRQLLT
HHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYERVEKHVLLFKNKSKGL
HHHHHHHHHHHEECCCCCC
>Mature Secondary Structure 
SFSQFNIDIFRAINDLGKQYSFLNPAIVFLAEYMVYMFALIILAYWFTRSRKSRMMVIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
AMVAFVIAEVIGKLAGKFHLNYQPFAVLPHVNKLVDHAVDNSFPSDHTILFFSICFSFWL
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
VRKKTGWLWLILAFCVAISRIWVGVHYPLDVAVGALIGCISAVFSHWLVPKLSFIRQLLT
HHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYERVEKHVLLFKNKSKGL
HHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476193; 9427658 [H]