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The map label for this gene is dapA [H]

Identifier: 52142683

GI number: 52142683

Start: 2680538

End: 2681434

Strand: Reverse

Name: dapA [H]

Synonym: BCZK2557

Alternate gene names: 52142683

Gene position: 2681434-2680538 (Counterclockwise)

Preceding gene: 52142681

Following gene: 52142684

Centisome position: 50.58

GC content: 36.34

Gene sequence:

>897_bases
ATGAAAAAAATTCAAGGGGCATTTCCAGTATTAATCACACCAATGGATGAGTTTCAAGAAATTAATTGGAACGGTGTAAA
ACAAAACGTAAACTACTTTATTGAGCAAAAAGTGGCTGGCATTATTATAAACGGAAGCACAGGAGAGTTTGTTAGTTTGT
TAAAAGAAGAACGATTTAAAATGGTAGAAACAGTATTAAAAGAAGTTAATGGCCGTATTCCGGTTATTGTTGGAACTGCA
GCAGAAACGACGAAAGAAACGATTGAATTTACAAAACATGCAGAAACGCACGGAGCGGACTGCGCATTAATTATTAACTC
ATACTATTGTAAGCCAAAAGAAGAGGAAATTTATTTTCACTTTAAAGAAATCTCAAATGCTGTAAATATACCAATTATGT
TATATAATAACCCGTTTACATCTGGTGTTGATATGAGTACAGAACTCATGCTACGTATCGGGAAAGACTGTGAAAATGTT
ACACATATTAAAGAATCTAGCGGAGATATTCGAAAAGCGAGAGATTTAGTAAGACAAGGCGAAGGTGCTTTTCAAGTATT
CTGCGGATCTGAAGATTTAGTTATGGAATCTTATTTAGTTGGTGCGACGGGATGGGTTTCAGTAGCAGGGAATATCGTAC
CGGGGCTTGTTACGAAAATGTATGAGCATTTTCAAAATGGTGAATTAGAAAAAGCTTGGGAAATAAACGATGCGATTTTA
CCTCTTTGCGAGTTTCTTGAAGGATCAGGAAAGTATGTACAAATCGTGAAACGCTCAATGGAATTATACGGGCAAGCTGG
AGGACCTTCACGTTATCCGAGACTCGGATTAACTGAAGAAGAAGATCAAAAACTTCAAACGATTTTATCAAAAATTGCAG
CACATGCGGCTGTTTAA

Upstream 100 bases:

>100_bases
AGAGGTTTTATTACAGGGGTGCAGACATTTCTACTAGACCCTACAGATCCATTTCCAGCAGGATTTTTATTAAAATAAAA
TGATAAAGGGAGAGATAAAT

Downstream 100 bases:

>100_bases
TTAAGGAGGAGAGCGTATATGTTAACGACAAATATTGAGCTGAAGCCAAAAGTGAAAGCGTTTTTAGACGAAGAGATTAA
AATGTTTATTAATGGTGAAT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MKKIQGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLLKEERFKMVETVLKEVNGRIPVIVGTA
AETTKETIEFTKHAETHGADCALIINSYYCKPKEEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENV
THIKESSGDIRKARDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNIVPGLVTKMYEHFQNGELEKAWEINDAIL
PLCEFLEGSGKYVQIVKRSMELYGQAGGPSRYPRLGLTEEEDQKLQTILSKIAAHAAV

Sequences:

>Translated_298_residues
MKKIQGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLLKEERFKMVETVLKEVNGRIPVIVGTA
AETTKETIEFTKHAETHGADCALIINSYYCKPKEEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENV
THIKESSGDIRKARDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNIVPGLVTKMYEHFQNGELEKAWEINDAIL
PLCEFLEGSGKYVQIVKRSMELYGQAGGPSRYPRLGLTEEEDQKLQTILSKIAAHAAV
>Mature_298_residues
MKKIQGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLLKEERFKMVETVLKEVNGRIPVIVGTA
AETTKETIEFTKHAETHGADCALIINSYYCKPKEEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENV
THIKESSGDIRKARDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNIVPGLVTKMYEHFQNGELEKAWEINDAIL
PLCEFLEGSGKYVQIVKRSMELYGQAGGPSRYPRLGLTEEEDQKLQTILSKIAAHAAV

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=287, Percent_Identity=25.4355400696864, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI13540533, Length=279, Percent_Identity=31.1827956989247, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI87082415, Length=267, Percent_Identity=28.0898876404494, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1786463, Length=263, Percent_Identity=28.1368821292776, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788823, Length=237, Percent_Identity=29.535864978903, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789620, Length=235, Percent_Identity=24.6808510638298, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33284; Mature: 33284

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00665 DHDPS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIQGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLLKEERFK
CCCCCCCCCEEECCHHHHHHCCCCCHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHH
MVETVLKEVNGRIPVIVGTAAETTKETIEFTKHAETHGADCALIINSYYCKPKEEEIYFH
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHEEE
FKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENVTHIKESSGDIRKARDLVRQG
HHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC
EGAFQVFCGSEDLVMESYLVGATGWVSVAGNIVPGLVTKMYEHFQNGELEKAWEINDAIL
CCCEEEEECCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHH
PLCEFLEGSGKYVQIVKRSMELYGQAGGPSRYPRLGLTEEEDQKLQTILSKIAAHAAV
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIQGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLLKEERFK
CCCCCCCCCEEECCHHHHHHCCCCCHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHH
MVETVLKEVNGRIPVIVGTAAETTKETIEFTKHAETHGADCALIINSYYCKPKEEEIYFH
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHEEE
FKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENVTHIKESSGDIRKARDLVRQG
HHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC
EGAFQVFCGSEDLVMESYLVGATGWVSVAGNIVPGLVTKMYEHFQNGELEKAWEINDAIL
CCCEEEEECCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHH
PLCEFLEGSGKYVQIVKRSMELYGQAGGPSRYPRLGLTEEEDQKLQTILSKIAAHAAV
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]