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The map label for this gene is kipR [H]

Identifier: 52142527

GI number: 52142527

Start: 2833518

End: 2834267

Strand: Reverse

Name: kipR [H]

Synonym: BCZK2715

Alternate gene names: 52142527

Gene position: 2834267-2833518 (Counterclockwise)

Preceding gene: 52142525

Following gene: 52142528

Centisome position: 53.47

GC content: 35.07

Gene sequence:

>750_bases
ATGGTACAGTCCATTGATCGAGCGATAAGTATTATAAAGTTATTAAATTCTACTAATGAAAAAGAGTATTGGGCCATTTC
TGATATAGCGGACAGAACACATCTCCCAGTTAGTACAGTACATAGATTACTTAACTCTCTAATCGAGCATGGGCTAGTTA
CACAAATTTCAGAGACGAAACAGTACAAAATTGGACCAATGTGGATGGAAATAGGATTACGACAATTGGAGAAGGTAGAC
TACAGATCAGTCGCAAGAGAAGTAATGAAACGATTGGCCTATGAAGTGGAAGAAAGTGTTTATTTGAACATTCCAAATGG
AACACATTCTATTATTATTGAAAGAATGGATAGCCCTTTAAAAATTCGAGTTATTGATAACTTAGGGGAACAGATTCCTC
TTTCGATTGGTGCTGCAAATAAAACAATGCTTGCCAATATGAAACAGAATGAAATGGAATATATTGTTGAGCAGCTACTT
TCTGCTTTACCAGAACAAAAGCAAATTCTTCTTGATCAAATAAAGCAAATAAGAAACGAAGGATATGCTGTCAGTTATGG
AGAAAAAACAGAAGGGACAGCTTCAGTAGCTGCACCTATTATCGGATTTAATCATAAGGTAGTAGGAGCATTAAGTGTTG
GGTTAATTAGTCATCGCATTAATGATGATCGACTATCTTTTCTTATTAGTAAGGTAAAACAAGCAGCACATGAAATATCA
ATAAAAATCGGCAGTACATCAGAACTATAG

Upstream 100 bases:

>100_bases
TTAGAAAATTAAATAAAAAGATTGATTTCATTTCGAATGTTTGTTAAATTGATAGGTAATTGAGCGTGCTAACATATTAC
AAGTCAAGGAGAGGTGAGTT

Downstream 100 bases:

>100_bases
TTTTGATAGCTGTCGTCATTTTTTATTCATATACTGGAATTCGTTTTCATAATACGGAAAAATAGGGGGATTTATATGTC
AAAGTGGCAATCAAAAGAAC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETKQYKIGPMWMEIGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPLKIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLL
SALPEQKQILLDQIKQIRNEGYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
IKIGSTSEL

Sequences:

>Translated_249_residues
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETKQYKIGPMWMEIGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPLKIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLL
SALPEQKQILLDQIKQIRNEGYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
IKIGSTSEL
>Mature_249_residues
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETKQYKIGPMWMEIGLRQLEKVD
YRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPLKIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLL
SALPEQKQILLDQIKQIRNEGYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
IKIGSTSEL

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=249, Percent_Identity=26.5060240963855, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=25.609756097561, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=28.3400809716599, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=25.3968253968254, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789999, Length=256, Percent_Identity=22.65625, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788581, Length=253, Percent_Identity=24.901185770751, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27974; Mature: 27974

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETK
CCCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
QYKIGPMWMEIGLRQLEKVDYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCE
KIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLLSALPEQKQILLDQIKQIRNE
EEEEEHHCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
CCEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
IKIGSTSEL
EEECCCCCC
>Mature Secondary Structure
MVQSIDRAISIIKLLNSTNEKEYWAISDIADRTHLPVSTVHRLLNSLIEHGLVTQISETK
CCCHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
QYKIGPMWMEIGLRQLEKVDYRSVAREVMKRLAYEVEESVYLNIPNGTHSIIIERMDSPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCCE
KIRVIDNLGEQIPLSIGAANKTMLANMKQNEMEYIVEQLLSALPEQKQILLDQIKQIRNE
EEEEEHHCCCCCCEEECCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GYAVSYGEKTEGTASVAAPIIGFNHKVVGALSVGLISHRINDDRLSFLISKVKQAAHEIS
CCEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEE
IKIGSTSEL
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]