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The map label for this gene is yqcK [H]

Identifier: 52142342

GI number: 52142342

Start: 3028595

End: 3029032

Strand: Reverse

Name: yqcK [H]

Synonym: BCZK2900

Alternate gene names: 52142342

Gene position: 3029032-3028595 (Counterclockwise)

Preceding gene: 52142341

Following gene: 52142343

Centisome position: 57.14

GC content: 34.7

Gene sequence:

>438_bases
ATGAGATATGTTCACGTCGGTATAAACGTTACGAATTTAGAGAAGTCTATTGAATTTTATGAAAAAGTATTTGGTGTATC
ACCAGTTAAAGTGAAAACGGATTATGCAAAATTTTTATTAGAGACGCCAGGACTTAATTTTACGCTGAACGTACGAGATG
AAGTGAAGGGAAATCAGGTAAATCATTTCGGTTTCCAAGTGGATACAGCTGAAGAAATTACATTACATAAAGAAAGATTA
GAAAAAGAAGGTTTCTTTGCGCGTGATGAAATGGATACGACTTGTTGCTATGCAGTTCAAGATAAGTTTTGGATAACGGA
TCCTGATGGAAATGAGTGGGAATTCTTTTATACGAAAGCACATAGTGATGTTCACAAAATTGAAGAGTCATCATGTTGCA
CGACTGCAAATGAGGTAGCTAAAAATTCTTGTTGTTAA

Upstream 100 bases:

>100_bases
CTGTATCTTTAGAAAAACAGGGAAAGGTAGTTGCTGTTAAAATTTTGAGTTATTAATCAAAAAAAATTGATTAATGATAT
GTAAAGAGGAGGAATAAGGT

Downstream 100 bases:

>100_bases
TAGGAGATGGAAAATAAAATGAAACGCTTATCCTTTCTAGACCGATATTTAACATTATGGATTTTTCTAGCGATGGCTGT
TGGGATTGGTTTAGGGTTTG

Product: lactoylglutathione lyase, glyoxalase family protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRYVHVGINVTNLEKSIEFYEKVFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNQVNHFGFQVDTAEEITLHKERL
EKEGFFARDEMDTTCCYAVQDKFWITDPDGNEWEFFYTKAHSDVHKIEESSCCTTANEVAKNSCC

Sequences:

>Translated_145_residues
MRYVHVGINVTNLEKSIEFYEKVFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNQVNHFGFQVDTAEEITLHKERL
EKEGFFARDEMDTTCCYAVQDKFWITDPDGNEWEFFYTKAHSDVHKIEESSCCTTANEVAKNSCC
>Mature_145_residues
MRYVHVGINVTNLEKSIEFYEKVFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNQVNHFGFQVDTAEEITLHKERL
EKEGFFARDEMDTTCCYAVQDKFWITDPDGNEWEFFYTKAHSDVHKIEESSCCTTANEVAKNSCC

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2641 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 16738; Mature: 16738

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVHVGINVTNLEKSIEFYEKVFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNQV
CEEEEEECEEEHHHHHHHHHHHHHCCCCEEEEHHHHHHHEECCCCCEEEEECCCCCCCEE
NHFGFQVDTAEEITLHKERLEKEGFFARDEMDTTCCYAVQDKFWITDPDGNEWEFFYTKA
EECCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCEEEECCCCCCEEEEEEEC
HSDVHKIEESSCCTTANEVAKNSCC
CCHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRYVHVGINVTNLEKSIEFYEKVFGVSPVKVKTDYAKFLLETPGLNFTLNVRDEVKGNQV
CEEEEEECEEEHHHHHHHHHHHHHCCCCEEEEHHHHHHHEECCCCCEEEEECCCCCCCEE
NHFGFQVDTAEEITLHKERLEKEGFFARDEMDTTCCYAVQDKFWITDPDGNEWEFFYTKA
EECCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCEEEECCCCCCEEEEEEEC
HSDVHKIEESSCCTTANEVAKNSCC
CCHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895 [H]